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Medicines for joint arthritis

08 Aug 18

Pain relief: what are painkillers for arthritis and arthrosis, effective ointments, tablets and injections

Pain is perhaps the most common complaint of a patient with arthritis or arthrosis. It is this that significantly worsens the quality of life of people with such diseases. Fortunately, the pharmaceutical industry comes to the rescue with a large selection of medications that help the doctor achieve adequate pain relief during therapy.

Types of painkillers for arthritis and arthrosis

Painkillers prescribed for joint pain are divided into two large groups:

  • narcotic (opioid);
  • non-narcotic (non-opioid).
  • When choosing a medicine for his patient, the doctor moves from simple to complex, that is, he selects the drug depending on the severity of pain. In this case, the effect of the drug should be sufficient, but not excessive.

    For acute and rapidly growing joint pain, treatment can begin immediately with opioids, using them to quickly relieve pain, followed by a transition to non-narcotic painkillers.

    Narcotic analgesics for rheumatoid arthritis

    These painkillers are prescribed in the acute period for a short course. In addition to pain relief, they also have antispasmodic and hypnotic effects.

    Among the side effects:

  • nausea and vomiting;
  • weakness;
  • dizziness;
  • formation of dependence;
  • respiratory failure.
  • Attention! Opioids are contraindicated in respiratory failure, in old age and early childhood.

    The effect is achieved most quickly with intravenous administration - after 15 minutes. The effect lasts 3-4 hours or longer. When used orally, the effect is less pronounced and lasting.

    It has been established that the drug copes with pain in joint diseases in the same way as Diclofenac or Meloxicam, without causing the side effects characteristic of NSAIDs. The product is effective for articular syndrome, which accompanies many diseases.

    Treatment with Tramadol is prescribed if the main therapy does not have a sufficient analgesic effect, namely:

  • If increasing the dose of NSAIDs is undesirable due to the high likelihood of side effects.
  • If there are contraindications to the use of NSAIDs.
  • Thus, the doctor prescribes Tramadol in order to increase the effectiveness of pain relief and the safety of antirheumatic therapy.

    NSAID Pain Relief Tablets for Pain Relief

    Drugs in this group have antipyretic, analgesic and anti-inflammatory effects. The mechanism of their action is to block the enzyme cyclooxygenase, which is responsible in the body for the induction of inflammatory processes.

    Attention! Let me remind you that if you have any problem, you can seek advice from our specialists.

    Interesting to know! There are two forms of the cyclooxygenase enzyme: COX-1 and COX-2. COX-1 plays an important physiological role in the body, COX-2 is responsible for inflammatory reactions. The higher the selectivity of the anesthetic drug, i.e., the more it suppresses COX-2 without affecting COX-1, the less likely it is to develop side effects.

    With caution, drugs in this group should be taken together with drugs that affect blood clotting, since NSAIDs enhance the effect of anticoagulants.

    The most common side effects relate to the digestive system:

  • abdominal discomfort;
  • nausea or vomiting;
  • increase in liver enzymes in the blood.
  • NSAIDs are contraindicated for erosive and ulcerative lesions of the gastrointestinal tract, recurrent polyposis of the nose or paranasal sinuses, bronchial asthma, as well as intolerance to acetylsalicylic acid.

    Like all drugs of the NSAID group, it reduces the intensity of formation in the body of substances that cause inflammation, and therefore, as a result, swelling and pain. In addition, Nimesulide prevents the destruction of cartilage tissue, which is especially important for joint diseases.

    An effective anti-inflammatory drug that does not have a protective effect on cartilage tissue. Usually prescribed for oral administration once a day with food. The daily dose ranges from 7.5 to 15 mg.

    The action of the active component is less selective than that of previous drugs (they block both forms of the enzyme: COX-1 and COX-2), which increases the risk of side effects from the gastrointestinal tract, as well as bronchospasm.

    Has high selectivity. Inhibits COX-2; at therapeutic concentrations it has no effect on COX-1. May lead to fluid retention in the body by increasing its reabsorption in the kidneys; therefore, it should be used with caution in patients with heart failure.

    This drug is approved for use in children (from 3 months). Adults are allowed to take no more than 4 g of the drug per day. If the permissible dosage is significantly exceeded, irreversible changes in the liver may develop.

    Pain-relieving injections for arthrosis and arthritis of the knee and hip joint

    Intra-articular injection of glucocorticosteroids or novocaine blockades help to quickly suppress the inflammatory process, relieve pain and restore freedom of movement.

    Novocaine blockades

    With any pain syndrome, muscle spasm develops, which limits movement in the joint - the so-called pain contracture. If such a spasm does not go away over a long period of time, then irreversible changes can occur in the joint, it loses its former mobility.

    For joint diseases, novocaine blockades help not only reduce pain, but also increase range of motion.

    Corticosteroids into the joint

    Local corticosteroid therapy not only suppresses pain and inflammation, but also does not have the same side effects and contraindications as when taking hormones orally.

    Pain-relieving ointments and gels for joint diseases: how to relieve pain from arthrosis and arthritis

    In addition to injections and tablets, topical preparations - ointments - are very effective for joint pain, complementing the main treatment. In addition, when used locally rather than systemically, the side effects of many medications are less likely to occur.

    Topical NSAIDs. The ointment reduces morning stiffness, relieves pain, and increases range of motion. A pronounced anti-inflammatory effect develops only by the end of the first week of regular use.

    A non-steroidal anti-inflammatory drug with a similar effect to Indomethacin. If you do not feel better after using the ointment for a week, it is recommended to consult your doctor. There are many products containing diclofenac, here are some names: Voltaren, Diclak, Diclogen, Olfen, Neodol, Diclomax.

    Gel based on ketoprofen (also an NSAID) for all types of joint syndrome: gout, rheumatic diseases, osteoarthritis, etc. The drug can be used in physiotherapeutic procedures (phonophoresis).

    This product is made from plant origin. It has local irritant, antiseptic and distracting effects. The main mechanism of action is the distracting effect of turpentine ointment; it does not have anti-inflammatory activity and is not recommended for intense swelling.

    Important! In no case do painkillers replace treatment with primary therapy drugs that directly affect its cause.

    You cannot use analgesics to dull the pain and have no effect on the disease itself, because it continues to progress.

    Painkillers for arthritis and arthrosis for children and pregnant women

    Most drugs are prohibited for use during pregnancy due to their negative effects on the fetus. If it is necessary to prescribe painkillers during lactation, breastfeeding should be abandoned. Paracetamol can be used from the NSAID group, as it is safe for the baby.

    Children from 6 to 12 years old are allowed to take local NSAID therapy in the form of ointments (for example, Diclofenac), as well as take Paracetamol tablets orally. Other drugs are prohibited for children under 15 years of age.

    The correct selection of an anesthetic is possible only by the attending physician, since the choice is influenced by the cause of the pain. There is no universal medicine that would work equally well for different types of joint pain.

    We offer for viewing an episode of the program “About the Most Important Thing” about joint pain and painkillers.

    In itself, pain relief does not affect the progression of the disease, since painkillers do not affect the cause of the disease. However, these funds are extremely important, as they increase the patient’s quality of life, improve his well-being and mood, and give him strength to continue making efforts to fight the disease. That is why adequate pain relief is an essential component of the treatment of patients with pain syndrome.

    Treatment regimen and choice of antibiotics for arthritis and arthrosis

    Osteoarthritis and arthritis are classified as pathologies that arise as a result of a sedentary lifestyle, improper metabolism, and injury to joints. Antibiotics are sometimes used for arthritis and arthrosis. But the treatment regimen is prescribed by someone who has worked with medications for more than one day, who knows the positive properties of the drugs and possible side effects.

    Features of joint diseases

    Arthritis is an inflammatory disease of the joints (large and small). Patients think about what antibiotics to take for inflammation of the joints, whether such medications are needed for this pathology.

    Antibacterial medications contain chemical agents that inhibit the growth of bacteria. They are used to combat many types of arthritis

    Experts have identified many types of arthritis, which are divided into 2 groups:

  • Aseptic. They are provoked by malfunctions of the immune system. The destruction of cartilage tissue occurs under the influence of antigens produced by the body. Antibiotic therapy for these forms of the disease is ineffective.
  • Infectious. It occurs due to an infection that has entered the body. I include a purulent, reactive, post-infectious form of joint damage. Treatment with antimicrobial agents is necessary to eliminate the root cause of the pathology.
  • Treatment of arthrosis also requires antimicrobial agents. Doctors prescribe such medications when arthrosis occurs as a result of arthritis. Cartilage destruction is not always accompanied by inflammation. This joint disease is characterized by a degenerative process. Antimicrobial agents are recommended for infections within the body of the affected compound.

    Arthritis symptoms

    Rheumatologists often record inflammation of the following joints:

  • elbow;
  • knee;
  • spine;
  • hip;
  • phalangeal joints of the feet and hands;
  • ankle
  • The disease is usually diagnosed in older people (35 – 50 years old). But even small children suffer from joint pathology.

    The patient is concerned about the following symptoms:

  • Pain localized around the affected joint and occurring after exertion or performing movements. In the later stages of the disease, the pain syndrome becomes constant.
  • Stiffness of the connection.
  • Swelling of the joint.
  • Forced position of the affected limb.
  • Redness of the dermis, increased local temperature.
  • Deterioration of condition.
  • Loss of natural mobility of the joint.
  • Principles of treatment of joint lesions

    Therapy of the affected joints is carried out comprehensively. This principle speeds up the patient’s recovery, helps cope with unpleasant symptoms, is considered the basis for the treatment of joints and includes the following therapeutic methods:

  • taking medications;
  • physiotherapeutic procedures;
  • physiotherapy;
  • massage (contraindicated during exacerbation);
  • Spa treatment;
  • methods of alternative therapy;
  • folk remedies.
  • In the treatment of rheumatoid arthritis, the rheumatologist selects a regimen according to the stage of the lesion and the characteristics of the patient’s body. The doctor uses tablets, ointments:

  • Analgesics.
  • NSAIDs.
  • Corticosteroids.
  • Immunosuppressants.
  • Chondroprotectors.
  • Antibiotics.
  • Biological response modifiers.
  • Glucocorticoids.
  • The use of tablets, ointments, injections in conjunction with procedures increases the effectiveness of medications. This is how doctors eliminate pain, inflammation, and swelling.

    Osteoarthritis causes inflammation of the joint and destruction of articular cartilage. Therapy for such joint damage is not complete without taking the following medications:

    1. Chondroprotectors (Rumalon, Dona, Glucosamine).
    2. NSAIDs (Movalis, Ibuprofen, Diclofenac, Ortofen).
    3. Vasodilators (Trental, Cinnarizine, Nicotinic acid).
    4. Muscle relaxants (Sirdalud, Baclofen, Mydocalm).
    5. Antibiotics for arthrosis are prescribed after complications, the development of the septic form of the disease. The remaining stages are not treated with antimicrobial medications. This disease is non-infectious.

      Antibiotic therapy for joint damage, choice of antibiotic

      Taking into account the nature of the inflammatory process, the doctor selects a course of treatment. If the cause of inflammation is autoimmune reactions, antimicrobial drugs are not used. If the connection is damaged due to an infectious infection of the body, broad-spectrum antibiotics are recommended.

      Antibacterial tablets do not eliminate the symptoms of acute inflammation and do not relieve pain. The action of these drugs is aimed at:

      • favorable treatment prognosis;
      • relapse prevention;
      • increasing the period of remission.
      • If doctors have not established the cause of the disease, the patient is prescribed a course of antibiotic therapy. The drugs are discontinued after an accurate diagnosis has been made.

        The course of antibiotic therapy is 7 days. The dosage is set individually depending on the degree of development of the lesion. Along with antibiotics for arthritis and arthrosis, medications are taken aimed at eliminating the negative effects of the components of antimicrobial drugs.

        Antibiotics for arthritis and arthrosis are chosen taking into account the method of infection penetration into the body and the sensitivity of the pathogen to the active substances of the medications.

        Let us indicate antibiotics for arthritis and arthrosis, which are used depending on the method of infection:

      • Fluorohydroxyquinolones, tetracyclines, macrolides. Medicines from these groups are used for infection through the genitourinary route. The most commonly prescribed medications are Minocycline, Tetracycline, Doxycycline, and Azithromycin.
      • Medicines of the penicillin, macrolide, and cephalosporin series. They are prescribed when the infection is caused by the upper respiratory tract. The most popular are Erythromycin, Amoxicillin, Cefotaxime, Ampicillin, Roxithromycin, Cefazolin.
      • Fluoroxyquinolones. Used for infection through the digestive system. From this group, Lomefloxacin, Ofloxacin, Sparfloxacin can be prescribed.
      • Antibiotic treatment regimen

        For the treatment of arthritis, arthrosis, in addition to antimicrobial agents, the doctor prescribes restorative, anti-inflammatory, and painkillers. Complex treatment lasts up to several months. Antimicrobial tablets are recommended to be used to destroy the source of infection for a week together with rheumatoid drugs.

        Rheumatologists can suggest the following antibiotic therapy regimen:

      • Azithromycin. Take the drug once, the effect lasts a week.
      • Doxycycline. Used in tablet form. Recommended for use twice a day, one tablet. Take the medicine daily.
      • Erythromycin, Ofloxacin. A complex of these medications is prescribed if it is impossible to eliminate the source of inflammation.
      • Amoxicillin. This drug is prescribed to strengthen therapy. You should take 2 tablets at a time. Three doses of medication per day for a week.
      • Antibiotics in the treatment of rheumatoid arthritis

        Antibiotics are used in the basic treatment of rheumatoid arthritis. The basis of basic treatment is the use of biologically active disease-modifying agents. Experts use:

      • Cytostatics Cyclophosphamide, Azathioprine, Consupren.
      • Antimalarial drugs. They are used for six months. This is due to the fact that antimalarial drugs have a slow effect. From this group, doctors prescribe Immard, Plaquenil, Delagil.
      • Drugs from the sulfonamide class (sulfasalazine). The duration of the therapeutic course can be a year.
      • Penicillins (tauredon, cuprenil, crizanol). Tablets of this class are prescribed when other medications from basic therapy are ineffective.
      • Side effects of antibiotics

        Do not overuse antibacterial tablets. Also, you should not prescribe antibiotic therapy yourself or take medications recommended by friends. Irrational use of medications in this group is dangerous. Drugs from this class have a number of negative effects:

      • Reduced body resistance to infections.
      • Immune suppression.
      • Problems with digestion.
      • Destruction of beneficial microbes that protect the body from penetration and proliferation of pathogens.
      • Disturbances in the functioning of the hematopoietic system.
      • Disturbances in the functioning of the nervous system.
      • You need to be careful with antibacterial tablets and ointments. Abuse of these drugs is just as dangerous as failure to use drugs in the treatment of joint diseases. Refusal of antibiotics can worsen the prognosis of the disease and cause death.

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        Diet and nutrition for arthritis

        The tissues in the body are renewed daily and are built from what we eat. Any type of arthritis associated with infection or excessive immune activity is an inflammatory process. Therefore, an anti-inflammatory diet for joint arthritis can be one of the means of reducing symptoms.

        Excess fat is the enemy of joints

        Excess weight puts undue stress on joints and increases the risk of wear and tear. But there is another reason why extra pounds are a problem. Fat is not an inert substance, but a metabolically active substance that can produce hormones and enzymes that increase the level of inflammation. Therefore, losing weight is not just a way to get rid of a big belly, but a targeted reduction in inflammatory reactions that hit the joints.

        The main restrictions of the diet against arthritis

        Proper nutrition for arthritis of the joints should exclude foods that provoke inflammation:

      • Saturated fats are found in beef or pork, poultry skins and offal, as well as whole dairy products (milk, sour cream, cottage cheese). They are also found in palm and palm kernel oils, which are part of any ready-made purchased goods: cookies, baked goods, bars, candies. It is necessary to sharply reduce their consumption, read labels in stores, choose skim milk, yogurts, lean chicken and turkey.
      • Trans fats were developed to extend the shelf life of baked goods. They directly cause the formation of fatty plaques, which impair blood circulation, including in the joints. Manufacturers list trans fats as ingredients on packaging.
      • Simple carbohydrates: sweets, breads and rolls made from white flour, white rice, cookies and other refined foods provoke inflammatory reactions in the body, increasing the production of pro-inflammatory substances. Limiting these foods can reduce arthritis pain and stop its progression.

    The main components of proper nutrition for joints

    The diet for arthritis of the knee, hip or any other joints is based on foods that can reduce inflammatory processes:

  • Omega-3 fatty acids are recommended for people with arthritis, arthrosis and other degenerative diseases. Sources of these compounds include salmon, herring, mackerel, sardines, anchovies, trout, flaxseed oil, walnuts, seaweed and soybeans. More than a dozen studies have shown that including fish oil in the diet for rheumatoid arthritis significantly improves health.
  • Olive oil is a good addition to healthy monounsaturated fats. It also contains the compound oleocanthal, which prevents inflammation in arthritis by blocking the pathways affected by ibuprofen and aspirin, the most popular pain medications. Olive oil is used in cooking instead of vegetable oil or butter (in equal or smaller quantities). The first cold-pressed product contains the most beneficial enzymes.
  • Antioxidants such as vitamin C, carotenes, and bioflavonoids protect the body from destructive free radicals that damage DNA. Any health-improving diet for rheumatoid joint damage must include plant sources of oxidative stress suppressors. Studies have shown that some of them slow down the development of the disease and prevent complications.
  • The best antioxidants are found in vegetables and fruits, which should be included in the diet for arthritis and arthrosis:

  • Vitamin C is found in sweet peppers, oranges, grapefruit, strawberries, pineapples, lemons, broccoli, cabbage, and potatoes.
  • Beta-carotene can be found in carrots, cabbage, pumpkin, melon, persimmons, tangerines, red sweet peppers, corn, oranges, apricots, carrots, and nectarines.
  • Quercetin is found in onions, cabbage, cherry tomatoes, broccoli, blueberries, black currants, elderberries, lingonberries, apricots, red apples, and purple grapes.
  • Anthocyanins enter the body along with blackberries, black currants, blueberries, eggplants, raspberries, cherries, grapes, strawberries, plums, cranberries, rhubarb and apples.
    1. Vitamin D is responsible for the production of many beneficial enzymes in the body. The menu for rheumatoid arthritis should contain a sufficient amount of it, as this will reduce the risk of complications and disability. A daily dose of at least 600 IU up to 70 years of age and about 800 IU over 70 years of age preserves muscle strength and strengthens cartilage, improves physical activity. Salmon, sardines, herring, milk and egg yolks will help balance your diet.
    2. Spices have an anti-inflammatory effect, so they should be included in the diet. Ginger is considered one of the popular folk remedies for arthritis because it relieves pain. Turmeric inhibits the synthesis of inflammatory chemicals in the body. They should be added to food for their pleasant taste and subtle aroma.
    3. Food to support muscles and bones

      One of the areas of nutrition for arthritis is the preservation of muscle mass, which supports the joints and relieves them:

    4. Dairy smoothies, mixed from skim milk with the addition of bananas and any berries in a blender, will be filled with calories and proteins.
    5. Homemade yogurt is made from low-fat milk and a lactobacillus culture. It will fill the body with potassium for bones and cartilage.
    6. Multivitamins are helpers for patients with chronic illnesses that cause loss of strength. Your doctor will help you choose the right combination.
    7. Fiber is important for good bowel function, as some medications cause constipation. Oatmeal with berries and bananas in the morning will be its optimal source.
    8. Fruits in the form of juices, salads from cruciferous vegetables, seasoned with healthy oils, should become part of the diet.
    9. Eat regularly, small and often (every 2-3 hours), try to count calories and not reduce the total energy value below 1500 kcal - all this will help the body cope with the disease.

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