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Varicose veins treatment Detralex

13 Sep 18

Instructions for use of Detralex 500 and 1000 mg

By taking Detralex tablets for varicose veins, you can significantly improve venous outflow and return the vessels to normal tone. The flavonoids included in the product are successfully used in clinical medicine for the treatment of chronic venous diseases.

Description of the drug and manufacturer

International name Diosmin + Gesperidine (Diosmin + Hesperidin), trade name - Detralex. Pharmacological group: venotonic drug. The manufacturer of Detralex is the pharmacological laboratory Servier from France or Serdix from Russia.

The tablets are oval in shape with a thin film coating. The top of the pill is pinkish-orange, yellowish at the break. There is a dividing strip on opposite sides.

According to RLS, Detralex does not contain psychotropic or narcotic substances, it is not an antibiotic and a non-hormonal drug.

Since 2009, a dosage of the drug has been registered in Russia: 500 mg, 28, 30, 56, 60 pieces. Since 2016, tablets for varicose veins have appeared in a dosage of 1000 mg, 27, 30 and 60 pieces per package.

Since 2017, the release form in the form of a suspension in individual sachets of 10 ml, 15 or 30 pieces per package, has been officially included in the drug register. The content of active ingredients in one sachet corresponds to a 1000 mg tablet.

There are no creams, ointments, gels, solutions or capsules produced under the same name.

The 1000 mg tablet consists of flavonoids (micronized) in the form of a fraction, 90% diosmin, 10% hesperidin plus auxiliary additives. The active components are classified as venotonic and venoprotective agents of plant origin. The composition of Detralex after oral administration undergoes active metabolism and is excreted in feces and urine. The half-life is 11 hours.

pharmachologic effect

Detralex is a phleboprotector that is able to increase venous tone, have an effect on hemodynamics and relieve edema. As a result, the distensibility of blood vessels decreases and blood outflow increases. The drug also strengthens the walls of capillaries, which reduces their permeability.

The optimal dosage of Detralex for varicose veins of any stage to achieve the required effect is 1000 mg per day. The therapeutic effect of the tablets has been proven during clinical trials. In patients with chronic varicose veins, the drug improves microcirculation and increases the resistance of the vascular wall.

Tablets are prescribed to treat the main manifestations of venous and lymphatic insufficiency, as well as to eliminate the symptoms of varicose veins and other chronic vascular pathologies. Indications for use of Detralex:

  • pain syndrome;
  • muscle contractions (cramps) of the lower extremities;
  • chronic “fatigue” in the legs;
  • a feeling of fullness in the lower extremities and a feeling of heaviness;
  • swelling in the legs;
  • changes in the structure of the skin and subcutaneous tissue due to trophic changes;
  • inflammatory processes in varicose veins;
  • violation of the integrity of the skin over the veins (trophic ulcers).
  • After oral administration, Detralex thins the blood and promotes blood circulation, preventing congestion. For prevention, tablets are taken in case of a threat of developing varicose veins and to prevent thrombophlebitis and thrombosis.

    Course of treatment and dosage

    Many patients don't know? how to take Detralex for varicose veins: before or after meals, in the morning or in the evening. The official instructions indicate that the tablets should be taken in the morning during meals.

    Dosage 1000 mg 1 time per day. The score on the pills is designed to be divided in half to make swallowing easier.

    The duration of treatment with Detralex for varicose veins reaches several months. Sometimes it takes 1 year. If symptoms return, the doctor may prescribe re-therapy with tablets.

    You need to take Detralex for varicose veins in accordance with the course prescribed by your doctor. Independent adjustment of the duration of treatment and dosage may provoke the manifestation of undesirable effects.

    The instructions and reviews of the drug Detralex for varicose veins of the legs do not contain data on cases of taking a large number of tablets at one time. An overdose requires immediate contact with a medical facility.

    Mostly venotonic can cause mild disturbances in the functioning of the stomach and intestines. During clinical trials, rare cases of effects on other body systems were noted. Side effects of Detralex:

  • headache;
  • dizziness;
  • slight malaise;
  • itching;
  • rash;
  • manifestations of allergies (swelling of the face and eyelids).
  • The abstract for the drug also reports extremely rare cases of Quincke's edema. If even one of the described undesirable effects occurs, you should stop taking Detralex for varicose veins and consult a doctor.

    If the described symptoms are accompanied by an increase in temperature, then this may be a sign of a separate disease not associated with taking pills for varicose veins.

    Instructions for use of Detralex for varicose veins do not recommend taking tablets if you are hypersensitive to diosmin and hesperidin. It is forbidden to take the medicine if you are intolerant of the auxiliary components and lactation. The use of tablets for children is not described. The drug does not increase blood pressure, so it is not prohibited for hypertension.

    Pregnancy and breastfeeding

    Phlebology does not have data on the excretion of Detralex in breast milk. There have been no reports of adverse effects on the fetus. Experiments on animals have not proven a teratogenic effect or effect on reproductive function.

    Due to the lack of sufficient data, Detralex can only be prescribed by a doctor during pregnancy and lactation.

    Drug interactions

    There were no interactions between the tablets and antibiotics and other drugs. But the instructions recommend that when prescribing Detralex, you should inform your doctor about taking any medications. The annotation does not contain information that the drug is compatible with alcohol.

    Detralex for varicose veins can be bought at any pharmacy chain. A prescription for vein medication is not required. The price of Detralex in a pharmacy depends on the number of tablets in the package. The drug in a dosage of 1000 mg can be purchased for 1230 rubles (30 pieces). For the same number of pills, but containing 500 mg of the substance, you need to pay an average of 607 rubles.

    Analogues of Detralex tablets are represented by drugs from the group of venotonics and venoprotectors containing diosmin:

  • Vasoket (Germany 690 rubles);
  • Venarus (Russia 705 rubles);
  • Diosmin (Russia 380 rubles);
  • Phlebaven (Russia 443 rubles);
  • Phlebodia 600 (France 898 rubles);
  • Phlebofa (Russia 750 rubles).
  • Prices are average for the same number of tablets per package.

    When purchasing a drug, you need to know how to distinguish Detralex from a fake. To do this, you should carefully examine the box. It should be hermetically sealed and bright in color. The font on the packaging should not be different and the text should be without errors. But the main difference between fakes is the lack of positive dynamics from the ongoing therapy for varicose veins.

    For safety reasons, you should not purchase the drug for the entire course of treatment at once.

    Venous circulation disorders respond well to treatment in combination with a healthy lifestyle. To achieve the expected result from treatment with Detralex tablets, you must try to fulfill the following requirements:

  • get rid of excess weight (if any);
  • limit prolonged standing;
  • do not abuse exposure to the open sun;
  • take regular walks;
  • use compression garments;
  • When working sedentarily, take breaks for light exercises.
  • I consider this drug effective only in complex treatment. The advantage is its availability; you can buy it without a prescription. Among the disadvantages is the high cost; patients do not want to spend money. If treated only with Detralex, the disease may relapse.

    Veronica Vladimirovna, Irkutsk

    As a surgeon, I believe that without surgery the effect in the treatment of chronic varicose veins is minimal. For preventive purposes and after surgery, I prescribe Detralex tablets quite often.

    Andrey Alekseevich, Moscow

    I developed varicose veins after my second pregnancy. The doctor said that it was impossible to do without surgery. I started taking Detralex tablets on my own. Three months have passed. Nothing has changed in appearance, but my legs have stopped swelling in the evenings.

    I took this drug at a dosage of 500 mg, two tablets every day. I have chronic varicose veins. After 6 months I quit because I didn’t notice any effect.

    Detralex saved me from developing thrombophlebitis. If it weren't for this medicine, everything could have ended badly. The phlebologist said that I came in on time. The course was prescribed for 3 months. Now I wear stockings all the time and my legs don’t hurt.

    What is better to take for varicose veins: Phlebodia 600 or Detralex? How to drink, analogues and course of treatment, instructions for using tablets

    There are a lot of special remedies for the treatment of varicose veins.

    Naturally, the easier the medication regimen, the greater the effectiveness of the treatment.

    Detralex can easily be classified as such. It is easy to use and gives good results (if used correctly).

    In this article we will try to figure out which is better for varicose veins, Phlebodia 600 or Detralex, and we will also talk about how to take Detralex for varicose veins.

    This drug is produced by Servier, located in France.

    Other countries sell this medicine under a different name: Variton, Venitol, Ardium, Daflon 500.

    The tablets are orange in color and covered with a thin coating. The inside of the pill is heterogeneous and looks loose. The basis of the drug is the active substance called diosmin (90%).

    The remaining 10% is hesperdin and additional components:

  • cellulose microcrystals;
  • stearic acid;
  • glycolysis;
  • microtalc;
  • iron oxide (food coloring);
  • glycerol.
  • The tablets are packaged in blisters (each containing 15 pieces). Detralex is classified as micronized drugs, in which the diameter of the microparticles is about two microns.

    Detralex is an effective phlebotropic drug that has a general effect on the entire body.

    Flavonoids content has beneficial effects:

  • diosmin quickly reduces venous pressure, eliminates congestion and reduces vascular permeability;
  • Hesperidin improves blood flow and strengthens blood vessels.
  • Important. Detralex normalizes capillary blood flow and prevents the occurrence of blood clots.

    Flavonoids are also combined with other substances, and this implies additional properties of the drug:

  • works as an anti-inflammatory agent. The formation of prostaglandins, which provoke inflammation, is suppressed. So, horse chestnut has an effect;
  • is an antioxidant. Prevents the formation of free radicals;
  • prevents leukocytes from adhering to the walls of venous vessels;
  • increases lymphatic pressure.
  • It can be argued that Detralex:

  • blocks inflammation;
  • restores lymph flow;
  • stimulates microcirculation;
  • prevents varicose transformation.
  • With regular use, there is a decrease in the symptoms of venous insufficiency. Pain sensations decrease, swelling of the legs decreases.

    Indications and contraindications

    The advantages of Detralex are::

  • high efficiency;
  • no serious consequences;
  • Can be used by pregnant women.
  • The drug does not affect mental reactions and is not contraindicated for driving a car where increased attention is required.

    But there are side effects:

  • sudden attacks of diarrhea;
  • unpleasant itching and even hives;
  • the appearance of a rash;
  • nausea;
  • headache.
  • If such unpleasant sensations occur, you must inform your phlebologist . Hypersensitivity to some components of the drug is also a contraindication.

    During lactation, taking Detralex is not recommended due to the lack of necessary studies. Read further in the article about how to take Detralex for varicose veins and how to replace Detralex for varicose veins.

    Detralex: instructions for use for varicose veins

    The question of how to properly take Detralex for varicose veins often arises among patients and their relatives.

    In order for the treatment result to be successful, you need to adhere to certain norms and rules of administration.

    Depending on the stage, Detralex is taken for varicose veins, observing certain conditions.

    It is necessary to combine the medication with the requirements of a certain lifestyle:

  • Sunlight should be avoided.
  • Limit physical activity.
  • Lose weight.
  • Regular walks.
  • Use compression stockings.
  • Compliance with these requirements while taking Detralex will allow you to successfully fight varicose veins.

    Be sure to inform your doctor about allergies and intolerance to certain medications.

    Duration of treatment

    Paying attention to the diagnosis and physical condition of the patient, the doctor determines the duration of taking Detralex. But it should be taken into account that the plant substances included in Detralex will not work in the short term.

    For the treatment of dilated veins with Detralex, there are various courses with different durations . Tablets for varicose veins Detralex according to the standard course are taken twice a day, one tablet, but not less than fourteen days.

    Another treatment option is also very popular - taking Detralex one tablet twice a day for the first two weeks. Then two tablets are also taken, but once a day.

    As for how to take Detralex for varicose veins before or after meals, you should consult your doctor on this issue.

    And now about how much Detralex to drink for varicose veins . The course of treatment with Detralex for varicose veins at the initial stage is two months and is repeated twice annually. The duration of treatment for varicose veins, in severe cases of the disease, when pain and cramps are present, can be more than three months.

    If trophic ulcers appear, taking Detralex for varicose veins will last at least six months. There is even an opinion that in case of thrombophlebitis or complex vein anomalies, the drug will have to be taken constantly. There will be no harm, since there is no dependence on Detralex, and it is easily tolerated when taken for a long time.

    The high effectiveness of the drug and its good tolerability have led to the popularity and widespread use of Detralex for varicose veins, even in severe forms of the disease. The drug is also perfect for prevention.

    To find out how much Detralex you should take for varicose veins for prevention, check with your doctor.

    Analogues of Detralex for varicose veins

    Is there a Russian analogue of Detralex for varicose veins? Yes, there are such drugs.

    The doctor may prescribe the following medications to the patient as an analogue:

  • Venarus and Venozol (tablets) are complete analogues.
  • Diosmin (sometimes powder).
  • Dioflan.
  • Antistax (capsules).
  • Phlebodia 600 (with increased diosmin content) is a partial analogue.
  • You can often hear the question: Phlebodia 600 or Detralex, which is better for varicose veins ? The prices of these drugs are still different. It is difficult to answer unequivocally which is better for varicose veins - Detralex or Antistax and Troxerutin.

    It is worth remembering that the use of analogues is possible only with the permission of the attending physician. If the phlebologist insists on Detralex, then you should not experiment and try to save on a cheaper product.

    The price of Detralex tablets for varicose veins is 600 rubles per package (30 tablets). A package of 60 tablets costs over 1,200 rubles.

    Based on positive patient reviews, we can say that Detralex is one of the most effective means for combating venous insufficiency . And although the price of the medicine for varicose veins Detralex is quite high, you should not neglect its use.

    We hope that this article helped you and you now know how long to take Detralex for varicose veins, what analogues of the drug exist, and how you can replace Detralex for varicose veins.

    How to properly take Detralex for varicose veins

    Varicose veins are a fairly serious disease that, in its advanced form, is difficult to treat. The disease is characterized by the formation of vascular occlusion, which leads to swelling of the legs and inflammatory processes. In most cases, the problem can only be solved through surgery. However, at the early stage of varicose veins, the drug Detralex has proven itself to be excellent. This article describes in detail how to take the medicine for varicose veins Detralex, side effects and the mechanism of action of the drug on the human vascular system.

    Effect of the drug Detralex on the body

    Lack of movement negatively affects the human vascular system. People leading a passive life are susceptible to advanced venous insufficiency. High load on the veins provokes the development of edema, blockage of arteries, increased blood clotting, failure and inflammation in the tissue. This makes varicose veins a real disaster for humanity.

    Modern pharmacology has in its assortment a large number of medications for varicose veins. At the initial stages of the disease, doctors prefer the highly effective drug Detralex, which has a multifaceted spectrum of effects on the human body.

    Experts conditionally divide varicose veins into 2 stages:

  • Stage 1. Characterized by the formation of spider veins.
  • Stage 2. In the absence of proper treatment, thrombus formation occurs in the veins.
  • Detralex drugs have proven themselves to be effective tablets for varicose veins at any stage. The result of using this medicine is visible in the near future, after starting treatment.

    However, the drug has a targeted mechanism of action, that is, it has a beneficial effect specifically on dilated vein pathologies; in case of complications, the drug is useless.

    The drug interacts well with other medications. It can be used in combination with anti-inflammatory ointments. The therapeutic effect of this will only increase.

    Phlebotropic tablets for varicose veins Detralex have an oval shape, the color of the drug is orange-pink. The anatomical shape of the medicine makes it convenient for use. The main component of the drug (90%) is the active substances diosmin. Diosmin - tones muscles, reduces vascular permeability, improves blood flow, thereby preventing blood stagnation, and the substance also lowers pressure in blood vessels.

    The remaining 10% was divided among themselves - hesperidin (activates blood circulation, strengthens the walls of blood vessels) and additional components, such as:

  • talc;
  • purified water;
  • magnesium stearate;
  • sodium carboxymethyl starch;
  • gelatin;
  • microcrystalline cellulose.
  • Auxiliary effects of Detralex tablets on humans:

  • Anti-inflammatory effect. The medicine blocks the interaction between the main sources of inflammation.
  • Activates leukocytes, reduces the concentration of white blood cells in damaged tissues, and blocks the release of harmful substances.
  • Has an antioxidant effect. The medicine regulates the formation of free radicals, which negatively affect the walls of blood vessels.
  • Indications for use

    The following symptoms are the basis for taking the drug:

  • change in color or texture of the skin. Varicose veins disrupt the nutritional process of the skin. The result is paleness, blueness, or redness. Detralex tablets are aimed at quickly restoring cellular nutrition;
  • swelling. They signal problems with microcirculation of lymph and interstitial fluid. The basis for this is veins that are inflamed and dilated by pathology. This symptom causes inconvenience to patients in everyday life. The main difficulty is related to the selection of shoes. Detralex restores lymph microcirculation and ensures ease of movement;
  • heaviness in the legs. If cellular nutrition fails, the limbs do not function fully. Even in a calm state, or with minor physical activity, the legs become heavy. A characteristic symptom of patients with varicose veins of the legs. If you seek medical help in a timely manner, the pathology can be quickly cured;
  • night cramps. Veins dilated by pathology put pressure on nerve endings. As a result, problems begin with contact between them. The symptom appears in the form of seizures. Sometimes, to get rid of the pathology, it is necessary to use strong painkillers.
  • Contraindications to the use of Detralex: individual intolerance to the components included in the composition and the period of breastfeeding. Taking pills can cause problems with the gastrointestinal tract, nervous system, and in extreme cases, allergic reactions. In order to prevent the occurrence of side effects, it is necessary to use the drug strictly as prescribed by the attending physician, with strict adherence to the instructions.

    How to take Detralex correctly for varicose veins? For each type of varicose veins, there is a special dosage regimen. Instructions for using Detralex for varicose veins of the legs: for the first 10 days you need to take the medicine day and evening, one tablet at a time. After this period, you can take Detralex 2 tablets at once, once a day. Taking Detralex for varicose veins of the legs ranges from 3 to 12 months. Cases of drug intoxication have not been registered.

    Due to its blood-thinning properties, Detrolex is widely used to treat varicose veins of the rectum. After using the drug, the walls of small arteries are strengthened and microcirculation in the affected area is normalized. Treatment with Detralex for hemorrhoids, complex.

    The drug is combined with anti-inflammatory ointments and painkillers.

    Instructions for use of Detralex for varicose veins of the rectum: In case of an attack of acute varicose veins in the rectum, the dose of Detralex is 6 tablets per day. Take 3 tablets during the day before meals or during meals and 3 tablets in the evening for 4 days.

    After acute attacks of the disease have passed, take 2 tablets during the day and 2 tablets in the evening for 3 days. Next, the medicine is taken according to the usual regimen, valid for varicose veins, the principle of administration is described above.

    Instructions for using Detralex for pelvic varicose veins: to get rid of this form of pathology, you need to take 2 tablets of the drug for 2 months. Take the medicine - 1 tablet during the day, 1 tablet in the evening with meals, to avoid the negative effects of Detralex on the stomach.

    Instructions for use of Detralex for varicose veins of the uterus: for this pathology, treatment begins with 2 tablets per day. After 10 days of taking Detralex, the dose is reduced to 1 tablet per day. Take the medicine during the day with meals. During pregnancy, the regimen for taking Detralex tablets and the course of treatment for varicose veins of the uterus is determined by the attending physician.

    As a preventive measure, Detralex is recommended for use for 1 month. How to take Detralex for varicose veins and how many tablets are needed is determined by the doctor, who is obliged to take into account the stage of the disease, the general condition of the patient, as well as the results of examinations.

    Compared to other analogues, the medicine for varicose veins Detralex has the following advantages:

  • does not have a negative effect on vital organs. Therefore it can be used for a long time. The duration of the course is determined by a specialist depending on the extent of damage to the veins;
  • used to eliminate varicose veins at any age;
  • A highly effective remedy for problems with blood circulation in the extremities at any stage. Therefore, the drug is often prescribed to eliminate advanced or acute venous insufficiency (AVI).
  • Specialists and patients include the following main disadvantages:

  • high price. For some, Detralex is unaffordable due to its high cost. But the price of the drug corresponds to its unique pharmacological properties and treatment effectiveness. User reviews fully confirm the effectiveness of therapy for pathological circulatory disorders and cardiovascular complications;
  • long course of treatment. The drug gives a therapeutic effect only after several weeks of use. If the patient is elderly and if varicose veins of the legs are at an advanced stage, accompanied by auxiliary complications, the result will appear only after a month of use. All these factors slow down the recovery process. Therefore, a positive result from therapy takes a long time. Despite the effectiveness of the drug, many consider this a disadvantage. Strict adherence to the drug dosage regimen gives excellent results even in advanced stages of varicose veins.
  • Recommendations from experts

    To enhance the therapeutic effect of the drug, for varicose veins, experts advise following the following rules:

  • Reduce time on your feet.
  • Wear therapeutic compression stockings to improve blood circulation.
  • The diet should contain foods containing large amounts of selenium and iron (buckwheat, offal, seafood, apples, pomegranate, walnuts, peanuts).
  • Regular sunbathing.
  • Rejection of bad habits.
  • Hiking, outdoors.
  • Avoid hot water procedures.
  • To avoid complications and not take things to extremes, at the first signs of varicose veins, you need to immediately seek medical help. Because the result depends on how quickly the attending physician prescribes treatment. An advanced form of varicose veins can only be eliminated surgically.

    Detralex: course of treatment for varicose veins and hemorrhoids

    Today, one of the pressing problems in medicine is varicose veins of the lower extremities. This, at first glance, is a simple disease, but not as harmless as it seems.

    It is characterized by clinical manifestations in the form of pain, heaviness in the legs, swelling of the legs, and cramps at night. There is also a pronounced cosmetic defect - spider veins, asterisks, dilated veins.

    Complications of varicose veins pose a serious threat to life and health. These include:

    Ulcer on the leg as a result of poor tissue nutrition

    Phlebologists have a whole arsenal of medications in their arsenal, and it is often difficult for patients to figure out which medicine is actually effective. One of these medications is Detralex.

    Treatment of varicose veins with Detralex gives excellent results, as proven by many studies and numerous positive reviews from patients. Below are instructions for use in chronic venous insufficiency, as well as comparative characteristics with other analogues and cost.

    Instructions for use

    General characteristics: cost, drug group, description, manufacturer

  • Cost 680.9 rubles
  • Detralex belongs to the group of venotonic and angioprotective agents.
  • Manufacturer: Servier, France
  • Composition: active ingredient: Diosmin 450 mg, Hesperidin 50 mg
  • Packaging: 60 tablets – 4 blisters of 15 tablets each
  • Packaging: 30 tablets – 2 blisters of 15 tablets
  • Detralex tablets are oval-shaped, pink-orange in color. The inside is pale yellow or yellow.

    Pharmacodynamics and pharmacokinetics

    Pharmacological action: Detralex maintains the tone and elasticity of the vascular wall, strengthens the walls of capillaries.

    Against this background, the phenomena of stagnation in varicose veins are reduced. Detralex also has a positive effect on lymphatic vessels, by improving lymph outflow.

    Pharmacokinetics: Detralex is completely eliminated from the body after 22 hours. The main part of the substance is excreted by the digestive organs, a smaller part is excreted by the kidneys. The rate of excretion decreases with impaired renal function or intestinal dysfunction.

    Dosage, course of treatment

    For the treatment of varicose veins, the required dosage is 2 tablets 2 times a day (at lunchtime and in the evening). You need to know how to take the drug correctly.

    It is imperative to adhere to the prescribed course to achieve a positive effect. After seven days of use, it is necessary to reduce the dose to 1 tablet 2 times a day.

    Thrombophlebitis and postthrombophlebitis syndrome

    For the treatment of thrombophlebitis and postthrombophlebitis syndrome, exactly the same treatment regimen is used. It should be noted here that Detralex for thrombophlebitis is used as an auxiliary drug and for prophylactic purposes (prevention of recurrent thrombophlebitis).

    This drug may also be prescribed in the preoperative and postoperative periods of phlebectomy.

    Duration of treatment:

    1. The course of treatment for varicose veins is prescribed for 2-3 months.
    2. For thrombophlebitis and postthrombophlebitis syndrome, the course duration is up to 6 months
    3. In the preoperative period, Detralex is taken for 4-6 weeks, and in the postoperative period for up to 3 months.
    4. When taken for prophylactic purposes, the drug is taken for one month. The attending physician decides how long to take it based on the severity of the disease, the patient’s condition, and the data of laboratory and instrumental examinations.

      Instructions from the box with the drug:

      Indications for use of Detralex are as follows:

    5. Symptomatic treatment of varicose veins: elimination of heaviness in the legs, pain, morning fatigue, swelling
    6. For the prevention of varicose veins and lymphatic insufficiency
    7. Symptomatic treatment of acute attack of hemorrhoids, chronic hemorrhoids
    8. Thrombophlebitis of the leg veins and postthrombophlebitis syndrome
    9. Preoperative and postoperative periods of phlebectomy
    10. Detralex has the following contraindications for use:

    11. Intolerance to the drug components
    12. Age up to 18 years
    13. Breastfeeding period
    14. Pregnancy
    15. The following side effects may be observed while taking Detralex::

      1. Digestive disorders (nausea, abdominal pain, diarrhea, vomiting)
      2. Allergic reactions (skin rash, skin itching, rarely angioedema)
      3. Neurological disorders (headache, dizziness, general fatigue)
      4. Side effects are not permanent and disappear after discontinuation of the medication. Here it is worth canceling the fact that in the studies conducted, in most cases, Detralex was well tolerated by patients.

        Overdose and drug interactions:

        No cases of overdose or clinically significant interactions with other drugs have been identified.

        No data on negative effects on the embryo were obtained in the experiments. But, due to the insufficient amount of data on this issue, the use of Detralex during pregnancy is possible only in vital situations.

        There is no data available on the excretion of Detralex into breast milk, therefore the use of Detralex during breastfeeding is not recommended.

        Driving a vehicle: Detralex does not affect psychomotor and behavioral reactions, therefore driving a vehicle is permitted.

        Alcohol compatibility

        During treatment with Detralex you must refrain from drinking alcohol.

        In Moscow pharmacies the price of Detralex is 30 tablets from 625 rubles, 60 tablets from 1250 rubles.

        How else can varicose veins be treated? (video)

        Today, there are many tablets for varicose veins on the market, including analogues of Detralex.

      5. Troxevasin (tablets, ointment, solution for injection)
      6. Antistax (tablets)
      7. Phlebodia (tablets)
      8. Venarus (tablets)
      9. Vasoket (tablets)
      10. Venozol (tablets, gel, cream)
      11. Anavenol (tablets)
      12. Venoruton (tablets and gel)
      13. Ginkor fort (gel, capsules)
      14. These are all similar drugs in their composition or mechanism of action. Detralex has Russian analogues: Venarus (manufacturer: Obolenskoye ZAO), Venozol (manufacturer: VIS LLC).

        The main active substance is Troxerutin. Has a venotonic effect. It has a decongestant, anti-inflammatory, antioxidant effect on the walls of blood vessels.

        A drug with a similar composition and mechanism of action similar to Detralex.

        A drug that contains only diosmin. Diosmin has a venotonic, anti-inflammatory effect. Thanks to this, the outflow through the veins and lymphatic vessels improves, and the fragility of capillaries decreases.

        It is a dry extract of grape leaves. This drug has protective properties. It prevents vascular permeability, which to some extent slows down the formation of edema.

        A drug based on hydroxyethylrutoside, a derivative of rutin. It has a phlebotonic and angioprotective effect. Improves the condition of veins and capillaries.

        A complex preparation containing gingko biloba, troxerutin, heptaminol hydrochloride. Improves the condition of capillaries, reduces pain.

        So let's try to understand what their differences are and which drug should be chosen for treatment.

        Venarus or Detralex?

        Both drugs are identical in their composition and principle of action. But, Detralex is an original drug manufactured using original technologies and meets all the stated requirements of the manufacturer.

        This drug is well tolerated, has fewer side effects and has a good therapeutic effect. Venarus is a cheap analogue and substitute for Detralex, which is inferior in its therapeutic effectiveness; side effects when taking this analogue occur more often. Therefore, the answer to the question “Detralex or Venarus, which is better?” - only one, Detralex.

        Vasoket or Detralex?

        The differences between these drugs are in their composition. Detralex contains diosmin and hesperedin, while Vasoketa contains only diosmin. And in this case, Dentralex is more effective, and therefore preferable.

        Here it must be said that when diosmin is combined with each other, the therapeutic effect of both components is potentiated (increased), which makes the drug highly effective. Vasoket prevents the appearance of edema, but it does not cope with pain in the legs, leg cramps, that is, what Detralex helps with.

        Troxevasin or Detralex?

        Troxevasin does not have the same effect as Detralex. With its use, it is only possible to temporarily relieve symptoms, but it is impossible to improve the condition of the venous wall, which means the disease will continue to progress.

        Troxevasin must be supplemented with other medications, which is no longer economically profitable for the patient. An important difference is that Troxevasin does not affect lymph flow, which again does not provide the same therapeutic effect as Detralex.

        Antistax or Detralex?

        The answer is clear and requires a lot of thought. Of course, this is Detralesque. Herbal preparations are significantly inferior in their therapeutic effectiveness not only to Detralex, but to other medications.

        Such treatment cannot serve as a primary treatment, but acts only as an auxiliary therapy. Such treatment is often not economically beneficial for patients. In addition, such drugs are not widely used in medical circles due to their low therapeutic effectiveness.

        Venoruton or Detralex?

        Venoruton has an effect only on veins and capillaries. It does not affect lymph circulation in any way. Against this background, treatment of varicose veins is incomplete. In this case, it is necessary to prescribe additional drug therapy, which is again economically unprofitable for the patient. At the same time, prescribing such a large volume of treatment is fraught with a greater likelihood of developing unwanted side effects.

        Ginkor Fort or Detralex?

        The drug does not have a therapeutic effect for symptoms such as swelling, heaviness and cramps in the legs. It has low therapeutic efficacy and has not been widely used in phlebology.

        In this article we talked about the unique drug Detralex, produced by a French company. A comparative analysis of various drugs from the group of venotonics was carried out. Based on everything, we can confidently say that by choosing Detralex you care about the health of your feet and economic benefits.

        We recommend that you read: Cream-wax Zdorov - cream for varicose veins

        How does Detralks work? (very clear, interesting video, we recommend you watch it)

        Detralex: course of treatment for varicose veins and hemorrhoids: 7 comments

        I began to experience severe swelling and pain in my legs, the venous network appeared in some places, thanks to Detralex I coped with these unpleasant sensations. On the doctor’s recommendation, I undergo treatment with a course of 2 months every six months so that varicose veins do not progress.

        I’ve been suffering with my legs for the 2nd week now, they swell and hurt, I’m thinking of taking this veinotonic.

        Hello! Thanks for your question. I can tell you with confidence that the drug Detralex is a very effective venotonic, since it can have a positive effect on the walls of blood vessels, increasing their tone, relieving swelling and pain, and preventing the formation of blood clots and stagnation of blood in the veins. Just the symptoms you described may indicate the initial stage of varicose veins, which is the easiest to get rid of, but which few people recognize in time. Therefore, taking Detralex at an early stage of the disease will help achieve the desired result in the shortest possible time. In addition, if there is no varicose veins as such yet, Detralex will help prevent its development. But you should know that it is best if you consult a doctor about this, since the doctor, during the examination, will take into account the characteristics of your body, having studied your anamnesis in detail. Perhaps he will recommend that you take another drug, an analogue of Detralex, or prescribe only ointments or gels for external use. You may need to undergo some tests. In general, self-medication is not recommended, but if you have already taken any drug from this group and it helped you to a small extent, and now you want to replace it with Detralex, then you can safely do this, because among its analogues, this drug really quickly and helps effectively

        I do not recommend drinking Detralex if you have stomach problems. My ulcer worsened because of him. I started drinking Venarus instead, but only after I had undergone stomach treatment. There were no such side effects from Venarus

        woman, don't tell tales. If you have stomach problems, you generally need to take anything with caution. In addition, no one has canceled individual intolerance to the components of ANY drug. in the Venarus of side effects so praised by you - a carriage with a trolley, judging by the instructions. Detralex is an excellent remedy, I have not had any problems with it or with my legs since I started taking it - absolutely none. and, by the way, in most cases it is enough just to adjust the Detralex dosage regimen with your doctor to avoid troubles, and everything will be fine

        I never completed a course of Detralex, as soon as it became easier, I immediately felt sorry for the money for pills. Phlebodia is much more convenient in this regard - its cost allows you to buy the entire package of 60 pieces at once, which is enough for a course, because you need to take a tablet per day.

        A good photo was chosen for the article, stimulating, you immediately want to be treated. But the detralex regimen is definitely not for me - I’m on the road all day, I don’t have time to take the medicine during the day. Phlebodia is really more convenient to use.

        What is more effective for varicose veins: Detralex, Venarus or Phlebodia?

        Venotonic drugs are the basis for complex treatment of varicose veins of the lower extremities and hemorrhoids. The most in demand are: Venarus, Detralex and the widely advertised product – Phlebodia 600.

        We will try to highlight all the positive and negative aspects of the drugs and compare what is more effective, according to reviews from patients and phlebologists.

        Description of the drug Venarus

        Russian-made medicine . It is an oblong tablet coated with a coating that is resistant to the acidic environment of the stomach. Its dissolution occurs in the intestines, where the active substances are quickly absorbed into the general bloodstream.

        The active basis of Venarus consists of two components: diosmin 450 mg and hesperidin 50 mg . Additional elements are: gelatin, cellulose, iron and magnesium oxides, starch. The main part of the drug is filtered by the kidneys, which is a huge plus for people with gastrointestinal diseases.

        Venarus is most effective in the early stages of the disease . Long-term course intake works in the following way:

      15. collagen fibers, which form the basis of the vascular wall of the blood and lymphatic systems, are compacted;
      16. along with large vessels, the capillary network is strengthened and its conductivity improves;
      17. the function of venous valves is restored, which reduces vascular distension;
      18. blood and lymph circulation improves, congestion in the pelvis and lower extremities disappears.
      19. The drug is often prescribed during pregnancy . In women who already have dilated veins in their legs, varicose hemorrhoidal veins often develop during this period. Venarus is absolutely safe for the fetus; it can be used as a therapeutic and prophylactic agent.

        In addition to the tablet form, the drug can be produced in the form of a gel for external use. It is prescribed in advanced cases, as an addition to a course of treatment.

        Description of the drug Detralex

        The French medicine is available exclusively in tablets . The basic composition of Venarus and Detralex is identical. Both contain as an active component a combination of diosmin 450 mg - hesperidin 50 mg .

        The advantage of Detralex is its special production technology. Its active ingredients are in the smallest (micron) sizes, which allows them to quickly penetrate the bloodstream, and accordingly the effect will appear much faster.

        The breakdown of the drug occurs under the influence of digestive juices, and it is excreted through the intestines along with feces. This has implications for people suffering from kidney disease. The therapeutic effect of the drug is due to the properties of its main components:

      20. diosmin thickens the venous wall, increases the elasticity of blood vessels, strengthens venous valves, thereby eliminating excessive stretching and normalizing blood flow;
      21. Hesperidin affects microcirculation, reduces the fragility and permeability of blood vessels, and eliminates congestion.
      22. Detralex has a therapeutic effect, increasing the tone of the veins, triggering regenerative processes in the vascular wall . The preventive effect is associated with the prevention of hemorrhoidal bleeding in the postoperative period.

        The use of the drug during pregnancy has undergone clinical trials and has not revealed any abnormalities in the condition of the woman or the fetus.

        Important! There is no data on the penetration of the drug into breast milk and its effects on newborns, since such studies have not been conducted.

        Phlebodia 600: composition and results of use

        Users are interested in the French drug Phlebodia 600 and the effect it has. This one-component drug contains 600 mg of diosmin as an active substance. Its peculiarity is its selective distribution in tissues; its largest quantity is observed in the veins of the small pelvis and lower extremities.

        Phlebodia belongs to the group of “flavonoids” - substances that improve blood flow and metabolic processes in the bloodstream. Prescribed for the treatment of acute and chronic varicose veins, under its influence:

      23. the tone of the venous wall increases, which eliminates excessive stretching of blood vessels and pain;
      24. the fragility and permeability of capillaries is reduced, microcirculation is stimulated, due to which stagnation is eliminated and inflammatory processes disappear;
      25. the outflow of lymph improves, which leads to a reduction in tissue swelling.
      26. The medicine has proven its effectiveness in the treatment of chronic forms of insufficiency . In this case, it is taken long-term as a prophylactic, which:

        • prevents the development of trophic ulcers;
        • eliminates swelling and pain;
        • allows you to slow down the process of change in the vascular wall.
        • The drug was highly appreciated by patients during pregnancy. But at the present time, Phlebodia 600 belongs to a group of drugs whose effect on the fetus is still being tested.

          Detailed comparison of venotonics

          To decide which drug is better and which one to give preference to, it is worth conducting a pairwise analysis, comparing the composition, features and final result.

          The drugs are recommended by phlebologists as interchangeable, and they really have a lot in common:

        • both come in tablets that must be taken with food;
        • for a long-lasting effect, a long course of treatment is required;
        • the composition of the medicinal products contains identical active ingredients in the same dosage (diosmin 0.45 g and hesperidin 0.05 g);
        • The half-life of both drugs is 11 hours, which determines the frequency of dosing (twice a day);
        • drugs are effective in the treatment of acute and chronic processes, prescribed for the prevention of trophic disorders;
        • approved for use during pregnancy.
        • Reference! Many experts prefer Detralex, while consumers choose Venarus.

          Why does this happen, and how does Venarus differ from Detralex:

        • Detralex, thanks to the micronized state of the active substances, has a therapeutic effect much faster (many patients note positive changes after the first week of use);
        • for Venarus this time doubles; as a rule, you need to take the medicine for 10 - 14 days to feel relief;
        • taking Detralex causes dyspeptic disorders much more often than its domestic counterpart;
        • the price of Venarus is two or even three times lower than the cost of an imported product, which often plays a decisive role in the “dispute”.
        • Given the identical composition and the same final result, many consumers do not want to overpay for an expensive imported product. But everyone makes the final decision independently, based on their individual reaction.

          Phlebodia 600 and Venarus

          Both drugs are classified as angioprotectors, that is, substances that seal and strengthen the vascular wall. Despite the common scope, there are significant differences between them . So what is the difference between Phlebodia 600 and Venarus:

        • due to the long half-life, the therapeutic dose of Phlebodia is 1 tablet per day (Venarus is taken twice);
        • Phlebodia contains the only active element - diosmin in the amount of 600 mg;
        • it turns out that a single dose of the active substance in the imported analogue exceeds its amount in Venarus. But the daily dose of the domestic drug is higher, since Venarus is taken twice a day, which is 900 mg per day;
        • 30 tablets of the domestic drug are cheaper than the same blister containing the French-made drug, but a course of Venarus is more expensive;
        • Phlebodia is prohibited for use by people under 18 years of age and during pregnancy.
        • Reviews from doctors and patients

          In the debate about whether Venarus or Detralex is more effective, doctors' reviews were divided. Some believe that the imported analogue is more effective, others are quite satisfied with the domestic product.

          Verenko A. S. General surgeon, 16 years of experience: Detralex is a good remedy. Quickly relieves symptoms of acute hemorrhoids. With varicose veins, the effect is not achieved as quickly as we would like. But patients note an improvement in their condition, a decrease in swelling and nagging pain. Good as part of complex therapy.

          Rubanov M.E. Vascular surgeon, 8 years of experience: I prescribe Venarus to my patients. An inexpensive and very effective drug that quickly eliminates the phenomena of venous stagnation and lymphostasis. Prevents the appearance of trophic ulcers. Allergic manifestations occur rarely.

          Dzhamalov I.O. Vascular surgeon, 9 years of experience: Detralex is a good phlebotonic for eliminating the symptoms of CVI (relieves edema, reduces the manifestations of varicose veins). But I don’t know of a single case where the drug actually cured venous insufficiency. This disease is treated with radical active measures.

          Romashova V.L. cosmetologist, 10 years of experience: I really like Phlebodia 600. Minimum adverse reactions, maximum results.

          Attention! Any venotonics should not be taken without consulting a specialist.

          Here are patient reviews about which is better, Detralex or Venarus for varicose veins of the legs.

          Maria, 47 years old: I have been suffering from chronic varicose veins for a long time. Nagging pain, swelling, swollen veins prevent you from living fully. The doctor prescribed Detralex and now, for more than a year, I have no problems. I take the pills twice a day and feel great.

          Anna, 38 years old: It’s a pity that I fell for advertising and spent such a sum on Detralex. I have never suffered from hypertension, and after taking the drug not a day goes by without high blood pressure. The doctor advised me to switch to Venarus, it works the same, and the pressure remains normal.

          Sergey, 45 years old: I have such a job, I’m on my feet all day. There were nagging pains and heaviness in the legs. I went to the doctor, he prescribed Detralex, but after several courses I replaced it with Venarus. The drug works the same way, and the price is two times lower.

          When determining the “best” drug, a person relies on his own feelings. But the opinion of a specialist cannot be ignored; any treatment requires medical consultation.

          Categories : Prevention

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