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Varicose veins phlebodia

15 Jun 18

Which is better: Phlebodia 600 or Detralex? Detailed comparison

Phlebodia 600 and Detralex are angioprotectors - drugs for the treatment of diseases of the heart and blood vessels. These drugs are used for venous circulation disorders: venous and lymphatic insufficiency, varicose veins and hemorrhoids.

There is no clear and simple answer to the question of which drug is better - Phlebodia 600 or Detralex, since their indications, therapeutic effects and many properties are very similar. Although there are minor differences in contraindications and dosage regimen, as well as differences in the pharmacological processing of the active components (which affects the rate of absorption of the active substances), which we will also consider further.

This article is a comparison of these two drugs according to their characteristics. I took the official instructions for these medications as the basis for comparison. This information will help you better understand how your medications work so you can discuss them with your doctor.

Hesperidin – 50 mg

To make the right choice, you need to consult a doctor - phlebologist. He will determine what is best for you based on your medical history, examination results and the presence or absence of contraindications.

At an appointment with a phlebologist

Further from the article you will learn how the angioprotectors Phlebodia 600 and Detralex differ, what similarities they have, the features of their use for varicose veins and much more regarding the use of these drugs.

Characteristics of the composition of the drugs

Both drugs contain the active substance diosmin. Another compound has been added to Detralex - hesperidin. Let's consider their therapeutic properties.

Hesperidin is a plant bioflavonoid (bioflavonoid is a natural chemical compound) that has many effects on the body. Among its therapeutic effects on the condition of blood vessels and blood, the following are distinguished:

  • strengthening blood vessels;
  • elimination of spasms;
  • reduction in fatty acids and cholesterol;
  • improving the rheological properties of blood (viscosity and fluidity);
  • reduction of inflammation;
  • providing an antioxidant effect.
  • Diosmin also belongs to the group of flavonoids. The pharmacological drug diosmin is an artificially modified hesperidin. Its use has the following effects:

  • enhancing the vasoconstrictor effect of norepinephrine - thus reducing the distensibility and capacity of blood vessels;
  • an increase in the number of contractions of lymphatic vessels;
  • increasing the intensity of contractions of lymphatic vessels;
  • weakening the ability of leukocytes to adhere to the vascular wall, eliminating the inflammatory process.
  • The combined action of diosmin and hesperidin reduces internal lymph pressure, reduces the lumen of lymphatic vessels, strengthens capillaries and normalizes microcirculation of blood and lymph.

    Therapeutic effects of drugs: which is better?

    According to the instructions for use, both drugs have pronounced venotonic properties. They help reduce the distensibility of veins, reduce the permeability of the vascular wall of capillaries, increasing their resistance to mechanical stress.

    Both Phlebodia 600 and Detralex restore lymph flow.

    Thus, the medicinal properties of the drugs are the same.

    The result of using drugs for varicose veins

    How quickly do medications work and are removed from the body?

    Angioprotector phlebodia 600 can be detected in the blood two hours after application. Its peak concentration occurs after about five hours. An increased level of detralex in the blood is detected 2–3 hours after consuming the drug.

    The rapid absorption of Detralex is explained by the peculiarity of the pharmaceutical processing of the active substance. Diosmin and hesperidin, which are part of Detralex, are micronized - this is a process of grinding the compound, allowing microparticles to penetrate the blood at a higher speed. Thanks to this, the effect of Detralex occurs faster.

    The mechanisms of drug elimination are different. Phlebodia 600 is excreted from the body mainly by the kidneys (79%), only 11% of the drug exits through the intestines. Removal of Detralex mainly occurs in the feces, and only 14% of the substances are excreted in the urine.

    Comparison of indications and contraindications of drugs

    The choice of drug for varicose veins also depends on the indications and contraindications. A comparison of the readings of Phlebodia 600 and Detralex is in the tables below.

    As can be seen from the table, the indications for use of Phlebodia 600 and Detralex are absolutely identical.

    No adverse effects on the fetus were found in studies of both drugs. But the use of both medications is not recommended in the first three months of pregnancy. In the second and third trimester, the use of Phlebodia 600 and Detralex must be coordinated with a phlebologist and obstetrician-gynecologist.

    Comparison of application features

    Both medications are taken orally.

    According to the instructions, the use of both drugs depends on food intake and time of day. Phlebodia 600 must be taken on an empty stomach, in the morning. Detralex should be taken at lunchtime and in the evening, and its intake should coincide with meals.

    The dosage of these angioprotectors is also different. The amount of Phlebodia 600 taken once a day is one tablet, that is, 600 mg of the active substance (diosmin) per day. The single dose of Detralex is also one tablet, but taking into account the double dose, the total content of flavonoids per day is 1000 mg (900 mg - diosmin).

    Based on the differences in the method of application, everyone can decide which drug is best for them.

    The duration of treatment in both cases is determined by the attending physician. He also establishes the need for re-treatment. Most often, the duration of therapeutic use of both drugs in the case of varicose veins is about two months.

    Due to the fact that both drugs have the same active ingredient, Phlebodia 600 and Detralex also have the same side effects:

  • dizziness,
  • headache,
  • nausea,
  • heartburn,
  • abdominal pain,
  • rash,
  • skin itching.
  • The most common of these effects are gastrointestinal disorders. However, in general, both drugs rarely cause problematic effects; Basically, their occurrence is a consequence of increased sensitivity of the body. If negative effects appear, as well as their intensification as you take the medicine, you must consult your doctor. It may be necessary to revise the treatment regimen and prescribe another angioprotector.

    In the instructions for use, special instructions regarding varicose veins are described only for Detralex. These are additional measures during the treatment period that will speed up the healing process for varicose veins:

    use of special stockings;

    avoiding hot rooms and long periods of exposure to the sun;

    reducing time spent on your feet;

    getting rid of excess weight.

    Although there are no such recommendations in the instructions for Phlebodia 600, it would be logical to assume that the same measures must be observed during treatment with this drug.

    Comparison of other drug characteristics

    I also compared additional characteristics of the drugs: manifestations of overdose, interactions with other drugs, conditions of sale and storage, and others.

    Among the methods of treating varicose veins and chronic venous insufficiency (CVI), conservative pharmacotherapy has become increasingly important in recent decades.

    One of the most effective areas of therapy is the use of flavonoids - angioprotective and venotonic substances, which:

  • strengthen the fibrous matrix of the venous walls;
  • increase the contractility of muscle cells in veins;
  • activate lymphatic drainage;
  • strengthen blood capillaries, preventing the “effusion” of fluid from surrounding tissues.
  • Diosmin preparations, including Phlebodia 600, occupy one of the key positions in the pharmacotherapy of diseases of the venous and lymphatic systems.

    Phlebodia 600 is a drug designed to increase the tone of small-caliber veins, improve lymphatic drainage and venous outflow of blood

    The pharmacological properties of Phlebodia 600 were established back in 1978, at which time it began to appear on sale, first in Europe. Since then, numerous studies and observations have been conducted on groups of patients taking Phlebodia, which have made it possible to establish the high effectiveness and safety of the drug.

    The active substance of "Phlebodia" is a semi-synthetic (synthesized from natural raw materials of plants of the citrus genus) flavonoid diosmin, of which there are 600 mg per tablet. This is the standard recommended daily dose of diosmin for CVI. Auxiliary ingredients of "Phlebodia" are: cellulose MK, talc, stearic acid, silicon dioxide. The shell contains hypromellose, macrogol 400 stearate, wax, E904, E1520, E171, red cochineal A (E124), E172.

    Phlebodia with varicose veins:

    1. Increases the tone of small-diameter veins without producing a vasoconstrictor effect on the arteries.
    2. Increases the reactivity of venous muscle cells to norepinephrine and, accordingly, their contractility.
    3. Strengthens the walls of capillaries and reduces their permeability.
    4. Improves lymphatic drainage and relieves swelling of the legs.
    5. Partially blocks the inflammatory response and reduces venous pain:
    6. reducing the ability of leukocytes to attach to the vein endothelium and their migration to nearby tissues;
    7. inhibiting the synthesis of free radicals and prostaglandins.
      1. Inhibits the synthesis of thromboxanes, reducing thrombus formation.
      2. Pain in the legs, swelling and heaviness gradually decrease, spider veins on the skin resolve and become rarer

        Clinical studies have recorded significant reductions in the manifestations of CVI (edema, venous pain, convulsions, sensory disturbances) in at least 85% of patients at various stages of the disease. There was a pronounced positive dynamics of trophic ulcers (in 67% of observed cases - complete healing, in 25% - a reduction in the area of ​​ulcers by at least half).

      3. symptoms caused by venous and lymphatic insufficiency (heaviness in the legs, venous pain, cramps, swelling, trophic disorders);
      4. as part of complex treatment for hemorrhoids.
      5. allergy to substances in the medication (usually to the dye “Red Cochineal A”);
      6. breastfeeding (there is no information on the effect of the drug in milk on the child).
      7. Possible side effects:

      8. allergies (usually urticaria);
      9. heartburn, nausea, stool disorders;
      10. vegetative-vascular symptoms – headache, episodes of dizziness (rare).
      11. While taking Phlebodia 600, the following side effects may occur: allergic reactions

        How to take Phlebodia for varicose veins

        In the absence of complications of CVI (thrombophlebitis, trophic ulcers), it is recommended to take Phlebodia 600 for 2 months. In complicated cases, the duration of treatment is determined by the doctor: for example, for trophic ulcers, the course of treatment can last up to six months. Regardless of the severity of CVI, the daily dose is 1 tablet of 600 mg.

        It is advisable to take Phlebodia with meals, which reduces the likelihood of heartburn and nausea.

        Note: the pharmacy chain sells “Flebodia” cream-gel containing diosmin, positioned as a cosmetic product produced by JSC “Dzintars”. You can also try.

        “Phlebodia” for varicose veins of the pelvis

        In women, dilatation of the internal veins of the small pelvis of greater or lesser severity is quite common. Varicose veins of the pelvis are often masked by gynecological diseases, manifesting themselves in constant pelvic pain, menstrual irregularities, pain during gynecological examination and during sexual intercourse. Pain also bothers postmenopausal women. Ultrasound allows diagnosing the dilation of the pelvic veins. The diagnostic criterion is an increase in the diameter of the main veins of the small pelvis.

        It is also important to note that this drug does not treat the manifestations of varicose veins, it only eliminates the symptoms of venous insufficiency and maintains the condition of the vascular walls

        Clinical studies of the use of Phlebodia according to the standard regimen (1 tablet per day for 2 months) showed a pronounced decrease in the diameter of the dilated pelvic veins and an increase in the flow rate in them in 75–84% of patients, regardless of the stage of the disease, as well as a subjective improvement in well-being. For varicose veins of the pelvic veins during periods of exacerbation, it is advisable to undergo a course of treatment that includes venotonics - including Phlebodia 600. And reasonable physical activity and performing a set of therapeutic exercises should become the rule of the patient’s life.

        Pregnancy is not a contraindication to taking Phlebodia 600. No harmful effects on a pregnant child or on the condition of a pregnant woman have been recorded over almost 40 years of use of the drug. 2-3 weeks before giving birth, Phlebodia is stopped and not resumed while the woman is breastfeeding.

        "Phlebodia" can be prescribed for placental insufficiency, for the prevention of bleeding during contraception using an intrauterine device, as well as after surgery to remove varicose veins.

        What is better for varicose veins - Troxevasin or Phlebodia? Troxevasin has a slightly different spectrum of action - it is an antiplatelet agent. It is used both as a venotonic and for resolving blood clots and hematomas, preventing the formation of blood clots (trauma, thrombophlephitis). Can be used both internally and topically. The appropriateness of using Troxevasin is determined by the doctor. Joint use is also possible: “Phlebodia” internally, “Troxevasin” gel externally.

        Analogues of Phlebodia 600 are two-component venotonics (diosmin + hesperidin): Detralex, Venarus, as well as tracing paper with Phlebodia - Phlebofa (RF) with a minimum of excipients and without dyes. All these drugs have a similar mechanism of action and comparable effectiveness. "Phlebofa" is a good alternative for people with intolerance to the excipients of "Phlebodia 600".

        Phlebodia 600 is sold freely, without a prescription. Price 30 tablets from 940 rubles or from 252 hryvnia. “Phlebofa” in Russia costs about 900 rubles.

        Reviews of Phlebodia 600 are positive from both doctors and patients. Many patients indicate that the above analogues are better suited for them. This is a matter of individual tolerance and personal preference, since the therapeutic effect of Phlebodia 600 and Detralex, Venarus, Phlebofa is almost the same.

        Phlebodia 600 against varicose veins

        Phlebodia 600 is a drug intended to increase the tone of small-caliber veins, improve lymphatic drainage and venous outflow of blood (does not increase arterial tone). Phlebodia 600 is used for varicose veins to relieve symptoms of lymphovenous insufficiency (swelling and heaviness in the legs, pain, trophic dysfunction) and to treat disorders of blood microcirculation. The main active ingredient diosmin is quickly absorbed through the gastrointestinal tract and is evenly distributed over all levels of the venous wall. It is excreted in urine, feces and bile by 92.5% (the peak activity of the drug occurs in the fifth hour after administration). Phlebodia can be taken by pregnant women (before taking Phlebodia 600 for varicose veins, you should consult a doctor), but not during breastfeeding, since there is no information on the penetration of the drug into breast milk.

        To treat chronic lymphovenous insufficiency, as well as to combat pain in the veins and heaviness in the legs, the drug is taken daily, 1 tablet before breakfast. The duration of the course of treatment is always determined by the attending physician based on the tests he has performed. Typically, phlebodia is taken for varicose veins for two months, in more severe cases up to four months. If you miss one or two doses of the medicine, its further intake and dosage do not change.

        The drug is especially effective for the initial manifestations of venous insufficiency in combination with troxevasin (an ointment against varicose veins) and compression hosiery. The effect of taking it occurs by the end of the first week of treatment. Leg pain, swelling and heaviness gradually decrease, spider veins on the skin dissolve and become less common, and the general condition of the veins improves.

        Pregnant women can take phlebodia for pelvic varicose veins up to the thirty-sixth week inclusive. It is also important to note that this drug does not treat the manifestations of varicose veins, it only eliminates the symptoms of venous insufficiency and maintains the condition of the vascular walls. Therefore, you should not hope that this drug will relieve you of external manifestations of varicose veins.

        Among the main analogues it is worth noting Venarus and Detralex. In both drugs, the active ingredient is diosmin, but they additionally contain the enhancing component hesperidin (strengthens the effect of diosmin). Per day, a person taking Phlebodia receives a dose of diosmin equal to 600 milligrams (one tablet per day), while when taking Detralex (two tablets per day) and Venarus (two tablets per day), a person receives a daily dose of 900 milligrams of diosmin and 100 milligrams of hesperidin, which enhances the effect of the main component.

        If we talk about cost, the cheapest analogue of phlebodia of the two drugs listed above is Venarus, its cost varies from 600 to 650 rubles for 30 tablets and from 1000 to 1100 rubles for 60 tablets. The cost of 30 Detralex tablets varies from 800 to 850 rubles, the price of 60 tablets from 1500 to 1600 rubles.

        Most people who took Phlebodia 600 for varicose veins speak positively about it, noting a significant improvement in the general condition of the veins, a decrease in pain in the legs, and a lack of heaviness and swelling of the legs. In rare cases, side effects include headache.

        Phlebodia-600: features of the treatment of varicose veins

        Varicose veins are one of the most dangerous diseases of our time.

        Varicose veins lead to the following problems:

      12. thrombophlebitis, that is, the blood collects in clots and blood clots form, which at any time can break off and lead to either death or blockage of the veins, followed by death and rotting inside the leg;
      13. the appearance of trophic ulcers.
      14. In most cases, people simply ignore the symptoms of the disease and do not turn to phlebologists. And this can have serious consequences for your health. The presence of varicose veins in women can be accompanied by other, no less serious diseases.

        Therefore, the presence of heaviness in the legs or the appearance of swelling serves as an alarm bell for a detailed examination of the body.

        Phlebodia-600: description of the drug

        When treating varicose veins, it is important to choose the right treatment. We would like to draw your attention to the fact that the use of folk remedies can only help in the early stages of the disease. But if the disease is advanced, you should resort to the use of medications, which only a doctor can select. As for the most effective drugs that are most often prescribed to patients, these include the venotonic drug Phlebodia-600.

        Taking the medicine helps reduce the dilation of veins and increases their tone. In addition, blood circulation improves, capillaries are strengthened, and the vasoconstrictor effect of adrenaline increases.

        As for the release form, Phlebodia-600 is available in the form of round, convex tablets. The tablets must be coated with a pink coating. The medicine is packaged in blister packs of 15 pieces. The cardboard package may contain two blisters and, in addition, instructions.

        Attention! If you have never used this product before, we recommend buying only one blister. After all, if the drug does not suit you, then at least you will have wasted half as much money.

        Phlebodia-600 for varicose veins: active substances

        According to the instructions, the active substance of this medicine is diosmin. This substance strengthens and protects blood vessels and belongs to the pharmacological group of flavonoids. It is worth noting the fact that this component is of plant origin, so the likelihood of an allergic reaction is much lower than when using completely chemical preparations. Thanks to its presence, lymphatic drainage is accelerated. As a result, blood clots do not form and blood does not stagnate in the veins.

        In addition, the tablets contain:

      15. microcrystalline cellulose. Thanks to its presence in Phlebodia-600, the body cleanses. It also has a beneficial effect on blood cholesterol levels;
      16. silica. Also used to cleanse the body and minimize the likelihood of an allergic reaction;
      17. stearic acid;
      18. talc.
      19. There is also a form of release such as cream. It should be applied to swollen areas of the legs once or twice a day. The composition of the cream is identical to the tablets, but the concentration of active substances is lower.

        Phlebodia-600: recommendations for use

        And the first thing you need to remember: before using Phlebodia-600, you need to consult a doctor. It is necessary! And besides, the instructions are required to be studied.

        The tablets are intended for oral administration. As for the dosage, you need to take one tablet in the morning on an empty stomach.

        The duration of treatment is two months. The medicine Phlebodia-600 is indicated for varicose veins of the small pelvis and varicose veins of the legs.

        If you miss taking a pill, the next time Flebodia-600 is taken in the same dosage and the same regimen. Under no circumstances should you increase the dosage because you missed taking it. This will only make your condition worse. As for the interaction of this drug with other drugs, such clinical studies have not been conducted.

        Therefore, you should discuss the possibility of such a combination with your doctor.

        Phlebodia-600: contraindications and side effects

        Since varicose veins are common during pregnancy, it is worth discussing the possibility of using this remedy during pregnancy. No side effects have been identified when taken during pregnancy. It is worth paying attention to the fact that consultation with both a therapist and a gynecologist is mandatory regarding the use of Phlebodia-600 in the second and third trimesters of pregnancy.

        Also, side effects after using Flebodia-600 include increased sensitivity to the components of the drug. This may be abdominal pain, nausea, headache. Possible heartburn. If such symptoms appear, stop taking the drug and be sure to consult a doctor.

        The drug Phlebodia-600 is intended for the complex treatment of varicose veins and to eliminate such manifestations of the disease as a feeling of heaviness in the legs, pain, and impaired blood circulation in the veins and vessels.

        As for the contraindications of Phlebodia-600, these include:

      20. intolerance to one of the components of the drug. In this case, an allergy may occur. Attention! If you suspect an allergic reaction, you should stop taking the drug and immediately consult a doctor;
      21. early pregnancy. Remember that in the early stages of pregnancy the baby’s nervous system is formed. Therefore, it is not recommended to take any medications during such a significant process;
      22. postpartum period, during breastfeeding. Remember that in this case, not only you, but also your baby will receive a dose of the medicine through milk. In this regard, the baby may develop allergic reactions;
      23. The patient's age is under 18 years. At such a young age, varicose veins are a signal of the presence of a more serious disease. Therefore, there is no need to treat the consequence. It is better to find the cause of this condition and eliminate it. And after it, varicose veins will disappear.
      24. The drug must be stored at a temperature not exceeding 30 degrees. Be sure to check the production date when purchasing. After all, the validity of the drug is three years. And it’s probably not worth reminding that it must be stored out of the reach of children.

        Remember that varicose veins are not only painful sensations, blue vein nodules, spider veins, and swelling. Such a deterioration in appearance can cause discomfort in society and even depression.

        In addition, such a disease is a direct threat to your full life and simply life in the full sense of the word. After all, varicose veins lead to blood clots. And this is very serious, it is a direct threat to life.

        Therefore, adhere to the treatment methods prescribed by your doctor until the symptoms of the disease disappear completely.

        It is also worth remembering about a healthy lifestyle and moderate physical activity. And in this case, you will forget what varicose veins are and why you need to take Phlebodia-600. Good luck!

        Tablets for varicose veins Phlebodia - French medicine

        Venous blood flows from the lower extremities through superficial and deep veins that communicate with each other. Various reasons can lead to disturbances in venous outflow and redistribution of blood from deep veins to superficial ones. In this case, the superficial veins become overfilled with blood, become tortuous and unattractively contoured under the skin.

        An increase in pressure in the veins and capillaries leads to the penetration of the liquid part of the blood from the vessels into the surrounding tissues - swelling occurs. Symptoms of chronic venous insufficiency gradually develop - a feeling of heaviness in the legs, muscle cramps. In advanced stages, trophic ulcers form - skin defects on the inner surface of the ankles.

        The original drug Phlebodia 600 for varicose veins contains the active substance – highly purified diosmin. Under the influence of diosmin:

      25. the venous wall is strengthened;
        • its permeability to liquid decreases;
        • venous outflow improves, blood stagnation is eliminated;
        • the synthesis of prostaglandins, substances that form venous inflammation, is inhibited;
        • the outflow of lymph from the lower extremities improves - swelling decreases;
        • blood circulation becomes more efficient, oxygen delivery to tissues is facilitated;
        • the diameter of the superficial veins decreases.
        • VARICOSE VEINS OF THE SMALL PELVIS

          This disease affects women after multiple or complicated births or inflammatory gynecological diseases.

          Varicose veins of the pelvis are manifested by chronic pain in the lower abdomen, sometimes by pathological vaginal discharge and urination disorders.

          HOW TO TAKE PHLEBODIA?

          1 tablet per day in the morning, on an empty stomach.

          More details can be found in the instructions.

          THE DOSES INDICATED ARE RECOMMENDATIONS. DIOSMIN IS CONTRAINDICATED IN IF YOU ARE ALLERGY TO THE DRUG, ALSO IN PERSONS UNDER 18 YEARS OLD, IN THE FIRST TRIMESTER OF PREGNANCY AND DURING BREASTFEEDING. OTHERWISE IT IS WELL TOlerated. SIDE EFFECTS ARE RARE. PHLEBODIA 600 CAN BE COMBINED WITH OTHER TABLETS, GELS AND OINTMENTS.

          You can find out information about the cost of the drug and availability in pharmacies in Belarus

          You can find out information about the cost of the drug and availability in pharmacies in Belarus at apteka.103.by or tabletka.by

          Before asking your question, visit the “Instructions” and “Answers to Questions” sections, FAQ (Frequently Asked Questions), perhaps your question already has an answer.

          Have questions? Ask your doctor!

          Leave your contact details and a specialist will contact you shortly

          AVAILABLE WITHOUT A DOCTOR'S PRESCRIPTION.

          THERE ARE CONTRAINDICATIONS AND SIDE EFFECTS.

          THE DRUG IS CONTRAINDICATED IN THE FIRST TRIMESTER OF PREGNANCY

          AND DURING BREASTFEEDING

          Medicine. As an advertisement

          Site owner: Representative office of the simplified joint-stock company "Laboratoire INNOTECH INTERNATIONAL" (French Republic) in the Republic of Belarus UNP 100220190

          Modern French drug

          The quality guarantee of French medicinal products is achieved through the use of numerous generally recognized standards (GMP, GLP, GCP, GEP), which allow the production of medicinal products that meet the most modern requirements.

          The initial stage of varicose veins (class C0 according to the CEAP classification) , which is characterized by the absence of visible changes in the veins, heaviness and rapid fatigue of the legs, night cramps, and sometimes mild swelling of the legs, which goes away after rest, may be observed.

          1 tablet per day is enough*

          Selective accumulation of diosmin and/or its metabolites in venous vessels reaches a maximum at 9 hours after administration and persists for 96 hours.

          * - consult your doctor to determine your treatment regimen

          Available without a doctor's prescription

          The drug is made from plant materials and is available without a doctor's prescription.

          Allowed during pregnancy

          Can be used in pregnant women in the 2nd and 3rd trimester for the treatment of varicose veins and hemorrhoids. The drug is stopped 2-3 weeks before birth.

          The first stage of varicose veins (class C1 according to the CEAP classification) , the venous network may be visible, there are no nodes yet. Telangiectasias are visible - spider veins that are formed due to the fusion of small dilated intradermal veins. They can have different shapes: tree-like; spiral; arachnid; pinpoint (up to 1 mm in diameter). This stage can last several years or several decades.

        • The owner of the website www.phlebodia.by (hereinafter referred to as the Site), as well as all information materials posted on it, including images, texts and other materials, is the Representative Office of the simplified type joint-stock company "Laboratoire INNOTECH INTERNATIONAL" (French Republic) in the Republic of Belarus (hereinafter referred to as - Company) (location: Republic of Belarus, 220007, Minsk, Voronyansky St., 50, building 4, office 110).
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        • Before using medications, you should consult a specialist and read the instructions for use.
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      To reduce symptoms and slow the progression of the disease, it is recommended to take Phlebodia 600

      The second stage of varicose veins (class C2 according to the CEAP classification) , which is characterized by the appearance of varicose nodes. The second stage of varicose veins has two options:

      C2A. It occurs without symptoms. That is, the veins are dilated, but this does not bother the patient in any way (except, perhaps, for an aesthetic defect).

      C2S. Symptoms occur: heaviness in the legs, fatigue, low exercise tolerance, pain in the calf muscles, night cramps.

      The second stage of varicose veins (class C2 according to the CEAP classification) , which is characterized by the appearance of varicose nodes. The second stage of varicose veins has two options: C2A. It occurs without symptoms. That is, the veins are dilated, but this does not bother the patient in any way (except, perhaps, for an aesthetic defect). C2S. Symptoms occur: heaviness in the legs, fatigue, low exercise tolerance, pain in the calf muscles, night cramps.

      The second stage of varicose veins (class C2 according to the CEAP classification) , which is characterized by the appearance of varicose nodes. The second stage of varicose veins has two options: C2A.1. It occurs without symptoms. That is, the veins are dilated, but this does not bother the patient in any way (except, perhaps, for an aesthetic defect). C2S.2. Symptoms occur: heaviness in the legs, fatigue, low exercise tolerance, pain in the calf muscles, night cramps.

      The third stage of varicose veins (class C3 according to the CEAP classification) , in which swelling is added to the symptoms characteristic of the first stages; they are present not only in the evening, but also in the morning (this indicates the formation of venous insufficiency)

      The fourth stage of varicose veins (class C4 according to the CEAP classification) , in which skin changes appear due to impaired blood circulation. It is presented in two versions: C4a. Hyperpigmentation of the skin, when the skin turns brown and sometimes turns black. Inflammation develops. Varicose eczema forms.

      C4b. Lipodermatosclerosis, i.e. dystrophic changes in subcutaneous fat, developing as a result of impaired blood supply to tissues; multiple scars form in it. Lipodermatosclerosis is manifested not only by thickening of the skin, determined by palpation, but also by an increase in subjective symptoms. This pathological process significantly increases the intensity of the pain syndrome.

      The fourth stage of varicose veins (class C4 according to the CEAP classification) , in which skin changes appear due to impaired blood circulation. It is presented in two versions:

      C4a. Hyperpigmentation of the skin, when the skin turns brown and sometimes turns black. Inflammation develops. Varicose eczema forms.

      The fifth stage of varicose veins (class C5 according to the CEAP classification) , which is characterized by the appearance of trophic ulcers, when the trophic ulcers heal, the disease returns to the fourth stage. The healing time for ulcers gradually increases, initially amounting to several weeks, then several months. In the end, they stop healing altogether, since the degenerative changes occurring in the skin and subcutaneous fat are irreversible. This is the main reason why it is recommended to treat varicose veins in the early stages.

      Fifth stage of varicose veins (class C5 according to the CEAP classification), a far advanced stage of varicose veins, which is characterized by the appearance of trophic ulcers; when the trophic ulcers heal, the disease returns to the fourth stage. The healing time for ulcers gradually increases, initially amounting to several weeks, then several months. In the end, they stop healing altogether, since the degenerative changes occurring in the skin and subcutaneous fat are irreversible. This is the main reason why it is recommended to treat varicose veins in the early stages.

      The sixth stage of varicose veins (class C6 according to the CEAP classification) , which is characterized by the appearance of active, never-healing ulcers (occurs in 0.5-1% of patients, develops in the absence of treatment)

      If you are not a medical professional, please leave this section.

      The information in this section is intended for medical professionals only.

      Do you suffer from varicose veins and don’t know how to treat them? Try Phlebodia 600, instructions for use

      Varicose veins or varicose veins are a disease affecting the structure of the vessels that supply blood to the heart.

      It is expressed in the loss of their original shape and volume under the influence of various factors:

    8. excess body weight;
    9. hormonal changes;
    10. hereditary predisposition;
    11. pregnancy status;
    12. low mobility and spending a long time in a standing or sitting position.
    13. The structures that have lost their hardness, the veins become deformed and become inflamed from the inside - stagnation of blood and lymph occurs, and excessive formation of leukocytes. The result is thrombosis, pain and discomfort.

      Parts of the body located below the waist are at increased risk, since they are additionally affected by the gravitational forces of the earth:

      However, there is a certain group of drugs aimed at restoring the structure of veins, capillaries, as well as their ability to move blood and lymph. One of these medications is Phlebodia 600.

      What does it help with? This medicine is an angioprotector that also improves microcirculation in the capillaries.

      In addition, the drug has an effect on:

    14. decreased elasticity and distensibility of veins;
    15. improving the tone of the vascular and lymphatic network;
    16. elimination of stagnation;
    17. reduction of swelling in tissues;
    18. reduction of inflammation of the endothelium (inner surface of blood vessels);
    19. decrease in leukocyte activity and thrombus formation;
    20. blocking the synthesis of cyclooxygenase enzymes (pain syndrome);
    21. vasoconstrictor properties of adrenaline and norepinephrine.
    22. The drug Phlebodia consists of 100% active ingredient - diosmin (flavonoid), in the amount of 600 mg.

      The medicine also contains auxiliary components:

    23. colloidal silicon dioxide;
    24. stearic acid;
    25. talc;
    26. microcrystalline cellulose;
    27. macrogol stearate;
    28. propylene glycol;
    29. titanium dioxide;
    30. ethanol 95°.
    31. In addition, the tablet shell contains E-additives with indices: 124, 171, 172, 464, 901, 903, 904.

      The appearance of the pills is convex on both sides, wrapped in a bright pink film.

      Pharmacokinetics of the drug

      Phlebodia is a medicine for oral use that begins to enter the bloodstream 2 hours after taking the tablet. Over the course of another three hours, the concentration of the drug in the blood increases and reaches its peak value 5 hours after taking the pill.

      A small amount of the active component also accumulates in other tissues - mainly in the lungs, liver, and kidneys. The maximum concentration of active diosmin in the walls of blood vessels is observed after 9 hours and this effect lasts for 4 days (96 hours).

    32. 79% - through urination;
    33. 11% - with bowel movement;
    34. 2.4% - with bile.
    35. What is it prescribed for? The drug is used in the treatment of:

    36. varicose veins of the pelvis and legs;
    37. acute attacks of hemorrhoids - as one of the components of therapy;
    38. venous and/or lymphatic insufficiency;
    39. disturbances in microcirculation of capillaries and their fragility.
    40. This eliminates the following symptoms:

    41. pain, swelling, cramps and heaviness in the lower extremities;
    42. pelvic pain syndrome, as well as discomfort in the lower abdomen;
    43. burning, itching, pain and bloody smears from the anal ring area.
    44. The drug has proven itself well in phlebology and therapy against acute hemorrhoids.

      Effect on reproductive functions

      Studies have shown the effectiveness of the drug in restoring the health of the reproductive organs in women.

      The use of Phlebodia has a beneficial effect on the venous system of the pelvis:

    45. increases blood flow to the uterus, simultaneously reducing congestion;
    46. constricts venous vessels in the uterus and ovaries;
    47. relieves pain;
    48. saturates tissues with oxygen.
    49. Thus, the drug Phlebodia prevents the development of thrombosis and ovarian hypofunction. Relieves pain and can promote fertile conception.

      However, each medicine has a limited area of ​​use:

    50. The drug should not be taken if you are allergic to any of the components (most often the body does not perceive E124).
    51. Pregnancy is not a contraindication to the use of Phlebodia, but only under the supervision of a doctor and not earlier than the second trimester. The medicine does not have a teratogenic effect on the fetus.
    52. Lactation is an obstacle to the use of the drug: its absorption into breast milk has not been studied.
    53. Phlebodia is not prescribed for children.
    54. Diosmin is relatively easily absorbed by the body and rarely leads to discomfort, but such cases do occur.

      The most common side effects relate to:

    55. Gastrointestinal tract (gastrointestinal tract) - heartburn, nausea and pain in the abdomen;
    56. CNS (central nervous system) - headaches;
    57. skin itching, rash.
    58. Phlebodia can enhance drugs with active norepinephrine and adrenaline, so they must be combined with great caution.
    59. Does it affect blood pressure? The medicine does not affect blood pressure and the speed of reaction to external stimuli.
    60. Phlebodia can be combined with moderate alcohol intake.
    61. Instructions for use of Phlebodia

      How to use? Varicose veins of the pelvis, uterus and lower extremities, as well as problems with lymph flow, are treated using the drug Phlebodia according to a very simple scheme.

      The tablet is taken once a day - on an empty stomach, preferably in the morning. How much to drink, course of treatment - 2 months.

      Important. Phlebodia is not used as an independent remedy for hemorrhoids. The effect of the drug on the veins of the rectum is combined with specialized gels, ointments, and suppositories.

      How to drink and what dosage? When treating an illness, take 2-3 Phlebodia tablets per day. It is taken with meals, and the duration of the fight against hemorrhoids is no more than a week. If you miss a pill, the next dose does not change and the course of treatment also remains the same.

      Nuances for pregnant women

      Phlebodia during pregnancy does not harm the health of the fetus or mother. Its use has a rather positive effect on the course of pregnancy.

    62. improvement of placental blood flow and hemodynamics;
    63. growth of new capillaries and blood vessels;
    64. reducing the fragility of existing capillaries.
    65. Manufacturer and release form

      Phlebodia is a drug from the French company Innotera Shuzi, available in cellular blisters of 15 tablets.

      How many tablets are in a package, there are 3 package sizes:

      The drug is produced exclusively in the form of pills, ointments and creams. We'll talk about how much it costs below.

      Approximate price of Phlebodia 600:

    66. 15 tablets - 550 rub;
    67. 30 tablets - 850 rub;
    68. 60 tablets - 1600 rub.
    69. Phlebopha or Phlebodia, which is better? Phlebopha is an absolute analogue of Phlebodia, made in Russia. The drug has not passed clinical trials. In addition, the medicine contains raw materials of not very high quality. Also, there is a high probability of adverse reactions of the body and low individual effectiveness against varicose veins and hemorrhoids. The advantage is a nice price.
    70. Venarus is a Russian drug with a combination of diosmin + hesperidin. The medicine is used to eliminate varicose veins, hemorrhoids and combat trophic ulcers. What is better Venarus or Phlebodia? Venarus is used according to a more complex scheme than Phlebodia. In addition, it has significant side effects. The price per package is lower than that of the French drug, but the course of use may be longer.
    71. Phlebodia is a quality medicine, as proven by a large number of different scientific and medical studies. He has a good reputation among phlebologists and proctologists, and is also readily prescribed in gynecology for pregnant patients.

      The drug is made from foreign raw materials and has a simple application regimen. Most reviews about the medicine are positive.

      Phlebodia 600 for varicose veins: composition, indications, how to take, drug analogues

      Phlebodia 600 is a drug that helps fight varicose veins in the legs. Phlebodia belongs to the group of angioprotective drugs. This means that the action of this drug is aimed at protecting and restoring already weakened veins that have lost their tone.

      The venotonic effect of the drug is caused by its component – ​​diosmin. This is an active substance that has a direct effect on the human body as a whole.

      The drug Phlebodia 600 has many analogues in its main component, but they all differ in a variety of additional (auxiliary) substances. The manufacturer of this drug is the French laboratory INNOTHERA CHOUZY.

      Release form and composition

      Phlebodia 600 is available in tablet form. The tablets are convex, round, 15 pieces in a blister. Usually a pack contains 1 or 2 blisters, that is, a package contains 15 or 30 tablets.

      The composition includes the active substance diosmin. The dosage of diosmin is 600 mg. Among the excipients, microcrystalline cellulose at a dosage of 910 mg, stearic acid - 50.05 mg, colloidal silicon dioxide - 3.5 mg and talc - 10.24 mg can be distinguished.

      Indications for use

      Instructions for use show this drug:

      • for trophic disorders of the lower extremities;
      • with venous insufficiency;
      • For thrombophlebitis
      • with heaviness in the legs;
      • with lymphatic insufficiency;
      • with superpermeability of capillaries;
      • with exacerbation of hemorrhoids.
      • When spider veins appear
      • Phlebodia tablets for varicose veins are contraindicated in patients prone to allergies. It is also undesirable for patients with chronic kidney and liver diseases to take this drug.

        Side effects include allergies, stomach upset, and headaches. Often this drug does not cause negative effects, so it can be taken during pregnancy, but only after consulting a doctor.

        Treatment of varicose veins is effective if the drug is taken correctly. Very often patients are interested in:

        “How often can you take this drug?”, or “How to take it: before or after meals?” The answer is of interest to many, so you can read this information further.

        The medicine must be taken one tablet before meals, preferably in the morning. The course of treatment is a month, in some cases – two months. This depends primarily on the extent to which the veins in the legs are affected and the degree of the disease.

        Phlebodia for varicose veins of the pelvis helps to increase the tone of the veins, as well as microcirculation of blood in them, has an anti-inflammatory effect, and helps reduce blood stagnation in the veins. However, such a medicine for varicose veins of the legs requires compliance with special rules during treatment. First of all, you should:

      • Avoid prolonged exposure to the sun.
      • Monitor your weight and try to reduce it as much as possible (if you are obese).
      • To walk outside.
      • Combine treatments (take pills, ointments and wear special clothing).
      • It is not easy to follow such rules, especially at first, but this will ensure effective and quick recovery and help avoid the negative consequences of a disease such as varicose veins.

        Methods of using the drug for various diseases

        Depending on the disease and its degree, dosages vary.

        During hemorrhoids, the drug is allowed to be taken 2 or 3 tablets per day. Take during meals. The course of treatment is 7 days.

        For hemorrhoids, this drug helps reduce the occurrence of hemorrhoidal veins, helps neutralize inflammation, pain and unpleasant feelings.

        This drug is indicated for use in combination with other venotonic drugs. Compliance with this treatment regimen allows you to:

      • slow down further progression of the disease;
      • prevent possible complications;
      • relieve pain and reduce swelling of the legs.
      • Phlebodia should be taken once a day before breakfast in the morning. The course of treatment is from 2 to 6 months, depending on the degree of the disease.

        During pregnancy, this drug is indicated for the treatment of chronic lymphovenous insufficiency in the last two trimesters of pregnancy (second and third trimesters).

        Please note that when taking Phlebodia, you must stop taking it 14 days before the expected date of birth. Overdose of drugs during pregnancy has not been identified. Feedback from patients during this period was positive.

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