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Structum arthritis

16 May 18

Structum 500 tablets - effective help for joints

The medicine, which has the Latin name Structum, is a chondroprotector with an active substance - chondroitin sulfate sodium salt. It is the basis of the structure of bone tissue and cartilage.

in the form of bright blue gelatin capsules (for oral administration), inside of which there is a white powder (the formation of lumps is allowed).

Order by phone: (099) 634-96-96 (096) 90-91-92-8

Drug Structum: description

Endogenous chondroitin, which helps maintain and restore the structure of cartilage and bones, is presented in the form of the drug Structum 500 and Structum 250. The number corresponds to the amount of the active substance in mg. By directly influencing the metabolic processes of the cartilage tissue of the joints, the medicine reduces degenerative processes in them and stimulates the production of glycosaminoglycans. Calcium loss also decreases and regeneration accelerates. Additionally, the development of inflammation may be reduced.

Using Structum tablets, you can reduce pain and also improve joint mobility, which is very important in the treatment of rheumatoid arthritis. It is also important that the effect can persist for a long time after completing the therapeutic course.

, there are the following indications:

The onset of degenerative changes changes the anatomy of the joints, provoking degenerative changes. Patients experience pain;

This disease of the intervertebral discs is characterized by severe pain, as well as pathological changes in the discs and vertebrae;

The effect of the drug is manifested in its ability to reduce pain, relieve inflammation, and slow down the processes of degeneration.

Many patients managed to significantly improve their quality of life after taking the drug.

In most cases, favorable

, speak about the pronounced effectiveness of this drug. Many patients managed to significantly improve their quality of life after taking the drug: the pain went away, the flexibility of the joints and back improved, discomfort (in the form of morning stiffness) decreased, and the need to use painkillers was reduced. It is not surprising that so many patients want to buy Structum - it is quite actively prescribed by treating specialists.

Of course, it should be noted that there are also opposite reviews about Structum tablets, which express that the drug did not help or that the effect of it is no better than its analogues, but which are more affordable in terms of price. However, let's not forget that this is a common phenomenon when there are two camps of adherents and not only in matters of health...

One thing is certain: it will be possible to achieve a good effect from treatment and, as a result, hear positive reviews about the drug Structum, only with properly developed complex treatment. Indeed, in parallel with taking chondoprotective drugs, during complex therapy, it is also necessary to perform correctly prescribed physical activity, in the form of gymnastics. This is necessary in order to ensure increased blood flow to the diseased joint, which will accelerate metabolic and recovery processes.

Structum - the price of healthy joints

Exhibited for a medicinal product

is not characterized as particularly low, but the efficiency justifies the cost. Also, for Structum, the price in Ukraine can fluctuate significantly - which means it is possible to select the most economical offers.

Features of use

All the nuances of use are described from the drug

, but it is worth mentioning: the advantageous difference between this particular drug and its analogues is that the chondroitin in the drug contains the highest degree of sulfate. This allows you to attract and then retain the greatest amount of fluid inside the cartilage, making the tissue elastic and resilient.

The very structure of the active substance is closest to human, and the low molecular weight allows it to best penetrate the synovial membrane and accumulate there. Thus, the therapeutic effect occurs quickly and is long-lasting and pronounced.

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Structum: instructions for use, reviews, price

Osteoarthritis and osteochondrosis are widespread in the modern world. Approximately twenty percent of the population worldwide suffers from these diseases. They are very difficult to treat, which takes many years. The new drug “Structum 500” can help get rid of these diseases, instructions for use and reviews of which will be presented below.

Composition of the drug Structum

This drug is a chondroprotector. It is designed to protect cartilage tissue from destruction. The drug contains chondroitin sulfate, which normally makes up cartilage tissue.

The drug has a therapeutic effect and, by stimulating the reproduction of hyaluronic acid, maintains the viscosity of the synovial fluid, which affects the structure of cartilage tissue. Due to the presence of an antiseptic effect, the medicine prevents inflammation.

The constituent components of the drug prevent changes in the structure of cartilage tissue and the degeneration of cartilage. The chondroprotector helps improve joint mobility and relieve pain, which, over time, completely goes away. The chondroprotector also strengthens bone tissue by depositing calcium in it.

Indications for use

What are Structum tablets for? The medicine is intended for the treatment of pathologies of the spine and joints:

  • Osteoarthritis of the spine and joints;
  • Osteochondrosis of joints and intervertebral;
  • Other degenerative-dystrophic diseases of the spine and joints.
  • Structum 500 mg is contraindicated for use in:

  • Pregnancy and lactation;
  • Under 15 years of age (no studies have been conducted);
  • Tendency to bleed;
  • Intolerance to the components of the drug.
  • The use of this chondroprotector is usually not complicated by side effects, however, in rare cases, they may occur. While taking the medicine, nausea, bloating, diarrhea, and constipation may occur. An allergic reaction to the drug, rashes and swelling is possible. If side effects do occur, then use should be discontinued.

    The drug is available in the form of coated tablets, blue capsules containing cream-colored powder and injection solution.

    How to use Structum? The doctor will tell you about the method of use and the required doses after diagnosis. The most common regimen for prescribing this chondroprotector is one capsule (500 mg) twice a day.

    The drug should be taken regardless of food, swallowing the capsule completely with plenty of water. In the initial stages of treatment (three weeks), the doctor may prescribe 1500 mg per day. It is better to take a capsule of half a gram and 250 mg at the same time in the morning and the same capsules in the evening. Further, the dose can be reduced to 500 mg.

    The duration of therapy depends on the severity of the disease and the initial condition of the patient and can last from three months to six months. Then a break is taken for four months and the course can be repeated again. The instructions for using Structum tablets are no different.

    The injection solution is intended for intramuscular administration. Injections must be given once every other day. The dose is 0.1 mg, and if well tolerated - 0.2 mg. A course requires 25-30 injections. If necessary, the same course can be carried out after six months.

    When will the drug start working?

    Absorption of the active substance occurs in the intestines after four hours. After five hours, the medicine will enter the cartilage and synovial fluid, where it accumulates. Due to the long accumulation period, the effect can be expected no earlier than three to four weeks. The therapeutic effect is observed for seven months, then the course of injections should be repeated.

    The price of Structum tablets fluctuates around a thousand rubles for sixty pieces. 500 mg capsules in the same quantity have the same price. The price of Structum injections is also one thousand rubles. You can purchase the drug at a pharmacy. The cost may differ by one hundred to two hundred rubles.

    Patient reviews about Structum

    “Since childhood, I have had problems with posture, so recently I began to experience pain and discomfort while moving. The doctor prescribed this medicine and massage. After four months the pain went away. But I can’t connect this specifically with the medicine, since I attended massage courses, so I don’t know what exactly helped”;

    Ekaterina Z., 56 years old:

    “I have osteochondrosis. I used this drug on the advice of my doctor. I completed the full course, however, there was no effect”;

    Alena E, 53 years old:

    “I suffer from osteoarthritis of the hip joint. The quality of life suffers greatly. I tried many different remedies. On the recommendation of a doctor, I purchased this chondroprotector. I drank it for five months. I began to live like everyone else! As the doctor said, I was lucky because I was one of those for whom the drug helps get rid of all the symptoms. Many doctors prescribe this drug in combination therapy”;

    “The doctor prescribed this medicine in connection with osteochondrosis. A couple of weeks after I started taking it, I began to feel a stabbing sensation in my right side. It turned out that liver parameters were elevated. I don’t drink or smoke, so the doctor couldn’t figure out what was wrong for a long time. It turned out that this was due to the chondroprotector. It turned out that there have already been similar cases and I was far from the first. Therefore, I recommend checking your liver while taking this medicine.”

    Structum: analogues are cheaper

    In Russia, analogues of Structum in tablets are as follows:

    • The therapeutic effect is provided by Chondroitin sulfate (Chondrolone, Chondroxide, Mucosat);
    • Chondroitin sulfate and Glucosamine (Teraflex, Artra) have a therapeutic effect;
    • Preparations based on natural ingredients: fish and animal cartilage (Piaskledin, Rumalon).

    As an alternative, Dona is a drug consisting of the same components, but its price is higher. But in terms of efficiency, Dona is more preferable.

    What is the price for analogues of Structum tablets?

  • Chondrolon – 699-920 rubles;
  • Chondroxide tablets – 451 rubles;
  • Mukosat – 466 rubles;
  • Teraflex 100 capsules – 1313 rubles;
  • Artra tablets – 644 rubles;
  • Piaskledin – 1087 rubles;
  • Rumalon – 1440 rubles;
  • Don - 1350 rubles.
  • Which is better: Dona or Structum?

    According to doctors, Dona has an advantage in terms of effectiveness. Also, the advantages of Dona are that it needs to be taken once a day, its effect is softer, high-quality European production. However, for each patient the drug must be selected individually, in accordance with the characteristics of the body and the disease. Therefore, it is impossible to answer this question unambiguously. The manufacturer of Structum is PharmFirma Sotex, the country of origin is Russia.

    Buy Structum 500: good reviews and low price, an effective remedy in the fight against ailments of the musculoskeletal system

    Ailments associated with the back and joints used to be a concern only for the elderly population. But at the moment, children and young people are becoming ill with these diseases. Therefore, high-quality treatment for groups of such patients is now very important. Structum 500 mg capsules are an effective remedy that protects the joints and cartilage of the body from disorders and various destructions.

    When should you use Structum?

    The composition of Structum tablets includes such a basic substance as sodium chondroitin sulfate or sodium salt, which is easily absorbed by the body due to its natural origin, allowing to normalize the condition of cartilage tissue. With the help of this product, treatment of joints has become more effective and qualitative.

    Experts prescribe the drug in the following cases:

  • •Treatment of arthrosis – for primary manifestations of osteoarthritis in the area of ​​large joints.
  • •Osteochondrosis in the intervertebral region.
  • •Various manifestations of ailments in the joints and spine.
  • The medicine Structum is very important for those suffering from joint problems, since the drug replenishes the missing elements of cartilage tissue and also maintains its structure.

    Features of dosage and existing forms of the drug

    The course of taking Structum is quite long. It is at least six months.

    After six months of taking it, take a break for several months. The daily dose is up to one milligram. Structum is taken two to three times a day, depending on the tolerability of its components and the treatment regimen developed by a specialist.

    The price of Structum 500 is quite high; it is produced by the French company Pierre Fabre . In addition, it contains mainly natural ingredients, which are always valued higher than chemical components.

    The principle of action of the drug Structum

    The basis of Structum is sodium chondroitin sulfate , which is perfectly absorbed by the body, helps correct the state of bone and cartilage balance, nutrients, as well as metabolism. Structum 500 and similar drugs for the treatment of joints are prescribed by specialists in special situations when an integrated approach to the current situation is required.

    Chondroprotectors such as Structum tablets can eliminate inflammatory processes and restore tissue regeneration. Thanks to natural components, the positive effect of Structum lasts for several months. Sodium chondroitin sulfate itself is a component of joint tissue and cartilage, so the body accepts it well.

    Sodium chondroitin sulfate perfectly supports the deteriorating structure of cartilage and joint tissue, restores it, reduces calcium loss, and improves the natural metabolic process in these systems.

    Structum 500 have unique abilities:

  • •eliminates inflammatory processes, reduces pain;
  • •improves the mobility of joint tissue, restores the functions of cartilage fiber;
  • •supports normal metabolism;
  • •accelerates the processes of removing harmful substances from bone and cartilage tissue, reduces pathological processes and tissue destruction.
  • to drink sodium chondroitin sulfate, despite its naturalness and fairly easy digestibility, strictly as prescribed by a specialist. For Structum, the instructions consider various circumstances with side effects and contraindications, which only a doctor can correctly take into account.

    Features of the use of the drug

    Structum should be taken with plenty of plain liquid.

    It is better not to use juices and carbonated drinks. During the course of treatment you should refrain from consuming alcoholic products.

    Structum receives positive reviews from both patients and doctors. But, despite all the good points regarding the action of the medicine, it has its contraindications and side effects.

    Existing contraindications and side effects of the drug Structum

    Natural components of Structum help solve many different problems with bone, joint and cartilage tissues.

    But, like many other drugs, this remedy has a number of contraindications:

  • •children under fifteen years of age;
  • •special sensitivity to the components of the product;
  • •pregnancy and lactation;
  • •illnesses of the thrombophlebitis category;
  • •poor blood clotting, tendency to various bleedings.
  • Possible side effects after using Structum are quite simple and fall more into the category of individual sensitivity of the body.

    Possible side effects:

    • •dizziness;
    • •vomit;
    • • constant itching of the skin, urticaria;
    • •rashes on the epithelium of various types;
    • •attacks of nausea.
    • In general, Structum has positive reviews. Such negative effects are quite rare, since it is quite difficult to exclude unexpected reactions of the body to various substances, even of natural origin.

      Nuances and special instructions for the use of the drug

      The unique natural elements of the drug, and especially its main component, help prevent destruction and destructive changes in cartilage and joint tissues. An ailment such as rheumatoid arthritis, the treatment of which requires a lot of time and effort, becomes easily curable with the help of Structum .

      The dosage for treating adults and children is the same. Its change depends on the individual tolerance of the components and the absorption of chondroitin sodium sulfate by the body. Usually the dosage is not increased, as this may worsen side effects. The specialist determines the adjustment and adjustment of the dose of the medicinal substance based on the patient’s well-being and the results obtained after a month’s treatment.

      The drug very carefully in case of bleeding or bleeding disorders . In relation to the area of ​​the kidneys, liver, heart and related systems, there are no contraindications or warnings, since the drug is not excreted and does not decompose into harmful or individual components. It has a natural texture that is completely absorbed by the body .

      The interaction of the drug with other drugs is quite complex and unique. Therefore, specialists should carefully study the instructions for it and take into account other features of the drugs, since experiments have shown that Strutcum can enhance the effect of certain groups of drugs.

      Existing analogues and substitutes

      The list of drug substitutes is quite extensive. There are two large categories of drugs - some will have the main element in their structure - sodium chondroitin sulfate , and others will be aimed at curing arthrosis.

      The first category includes:

      Artradol, Kartilag, Chondroxide, including ointments and gels, Chondrolone.

      The second group that can combat the manifestation of arthrosis includes:

      Actasulide, Artra, Rumanol, Ibuprofen, Ketonal, Nimesil.

      The list of existing substitutes is quite extensive, so buy an analogue of Structum by selecting the drug according to your capabilities. But when choosing substitutes, you should first of all consult with your specialist, since such a replacement may be ineffective.

      Instructions for use of the drug Structum and its analogues with prices and reviews

      Elena Polyakova, doctor

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        Structum is a drug for the treatment of diseases of the musculoskeletal system. Its action is aimed at regulating and restoring metabolic processes in cartilage tissue. Reviews indicate that a course of treatment with the drug helps eliminate the symptoms of joint damage, as a result of which their functioning becomes better. Let's look at how Structum works, what indications and contraindications exist for its use, as well as average prices.

        The drug is available in the form of capsules for oral administration. The active ingredient is chondroitin sulfate, and also contains auxiliary components. Considering the quantitative content of the active component, Structum is available in two dosage options. These are gelatin capsules of 250 and 500 mg. They are blue in color on the outside and contain a white or creamy powder inside. The drug has an effect on joints, and in particular on cartilage tissue. This influence lies in the fact that such a composition causes the following effects:

      7. Stimulation of regeneration.
      8. Anti-inflammatory effect.
      9. Analgesic effect.
      10. Chondrostimulation.
      11. Reducing calcium loss.
      12. Slowing down bone resorption and activating its restoration processes.
      13. Reducing pain.
      14. Increasing the mobility of the articular surfaces relative to each other and increasing the range of movements in them.
      15. Suppression of interleukin-1beta, which has a negative effect on the structure of cartilage.
      16. Activation of the production of proteoglycans and hyaluronic acid.
      17. Preventing compaction of cartilage tissue.
      18. That is, as a result of metabolic transformations, Structum stimulates the formation and development of the main cells of cartilage tissue - chondrocytes. The composition of the medicine promotes fluid retention. Thanks to this, the elasticity of the cartilage increases, and its shock-absorbing function is performed better. This effect is confirmed by reviews.

        However, the composition of the product affects not only cellular elements. The drug improves the formation of intercellular substance of cartilage tissue. Improved nutrition of cartilage is caused by stimulation of the formation of intra-articular fluid.

        When is it recommended and not recommended?

        The instructions recommend using Structum in the following cases:

        1. Arthritis.
        2. Osteoarthritis.
        3. Osteoporosis.
        4. Traumatic damage to elements of the musculoskeletal system.
        5. Osteochondrosis.
        6. Spondylosis.
        7. Contraindications include individual intolerance to the components included in the drug. Also, children under 15 years old should not take Structum. This is due to the fact that no significant clinical studies have been conducted regarding its use in children. It is worth noting that in childhood, joint diseases associated with degeneration of cartilage and articular surfaces can rarely occur, so there is no need to take this drug in children. A similar situation is observed for pregnant and breastfeeding women. In this regard, it is not recommended for this category of patients to take the drug.

          Method of use

          The instructions for use recommend taking Structum in a daily dose of 1 g. That is, if these are capsules with a dosage of 500 mg, then it would be optimal to take one tablet in the morning and one in the evening. Reviews note that this method of use is quite convenient.

          The duration of treatment is usually about six months. However, only a doctor can determine the optimal daily dosage, frequency and duration of taking the drug. It is worth noting that the positive effect can persist for 3 or even 5 months after completion of the course of therapy. If necessary, the doctor may prescribe a second course of treatment. But reviews note that, as a rule, one course is enough.

          The medicine should be used with caution in persons with a tendency to bleed. It is also important to remember that the drug can enhance the effect of anticoagulants, antiplatelet agents and fibrinolytic agents.

          Since the main component of the drug is a natural component of the structural elements of the joint, the development of side effects is rare. And even if they occur, their severity is small, and they disappear after discontinuation of the drug. During use, allergic reactions may occur in the form of urticaria, itching, and dermatitis. Dyspeptic disorders such as nausea rarely appear.

          Cost and similar means

          You can find analogues of the drug in the pharmacy. The most famous tablet forms are Dona and Teraflex. Their composition is similar. Reviews note that some of them are cheaper and therefore more accessible.

          It is difficult to clearly determine which of the proposed medicines is better. Reviews indicate the good effectiveness of such drugs. And this is not surprising, because they have a similar composition and mechanism of action. The table shows the price of the most popular analogues.

          The description is valid on 23.06.2014

        8. Latin name: Structum
        9. ATX code: M01AX25
        10. Active ingredient: Chondroitin Sulfate Sodium (Chondroitine Sulfate Sodium)
        11. Manufacturer: PharmFirma SOTEX (Russia)
        12. Excipient: talc.

          Capsule shell composition: titanium dioxide, indigo carmine, gelatin.

          250 mg capsules are available:

        13. 15 pieces in blisters; 4 such blisters in a cardboard package;
        14. 10 pieces in blisters; 3 such blisters in a cardboard package;
        15. 30 pieces in a polypropylene bottle; one such bottle in a cardboard package;
        16. 100 pieces in a polypropylene bottle; one such bottle in a cardboard package.
        17. Structum 500 mg is available in 12 capsules in blisters; 5 such blisters in a cardboard package.

          Tablets as a release form are not used in the production of the drug.

          pharmachologic effect

          Pharmacodynamics and pharmacokinetics

          Chondroitin sulfate is one of the main components of cartilage and bone tissue, joints, it helps maintain the integrity of cartilage due to:

        18. enhancing the anabolic effect of chondrocytes (activation of proteoglycan );
        19. suppression of the harmful effects of interleukin-1? on the structural components of cartilage;
        20. inhibition of excessive degradation of cartilage (by blocking elastase in tissues, reducing the activity of metalloproteases and increasing the activity of a metalloprotease ).
        21. Chondroitin sulfate improves the balance of the synovial environment by increasing the production of hyaluronic acid - thus maintaining the proper viscosity and density of the synovial fluid. Chondroitin sulfate also suppresses the development of inflammatory reactions.

          After taking the drug, more than 70 percent of it is absorbed in the digestive tract. The maximum concentration in blood plasma is observed after 3-4 hours, in synovial fluid - after 4-5 hours. Bioavailability is about 13%.

          Indications for use

          The medicine is used as part of complex therapy for degenerative pathology of the spine and joints ( intervertebral osteochondrosis , osteoarthrosis ).

        22. age less than 15 years (effectiveness studies have not been conducted);
        23. hypersensitivity reactions to the drug.
        24. from the digestive system: nausea , vomiting ;
        25. hypersensitivity reactions : urticaria , itching .
        26. Instructions for use of Structum

          Instructions for use of Structum 500 mg recommend taking the drug orally with water.

          For adults and children over 15 years of age, the medicine is prescribed at a dose of 1 gram per day or 500 mg 2 times a day - this is two capsules; it is wrong to say “ tablets ”. The optimal duration of the initial course of therapy is six months. The therapeutic effect of the drug lasts for 3-5 months, depending on the stage of the disease and its location. If necessary, repeated courses of treatment are allowed.

          Signs of overdose: rarely - vomiting , nausea , diarrhea hemorrhagic rashes may appear .

          Treatment: symptomatic therapy.

          If the drug is used simultaneously with indirect anticoagulants, fibrinolytics and antiplatelet agents , the effect of the latter is enhanced.

          Sold by prescription in Ukraine and without a prescription in Russia.

          Keep away from children. Store at temperatures up to 25 degrees.

          The drug should be used with caution in patients with a tendency to bleeding.

          Admission to persons under fifteen years of age is prohibited.

          During pregnancy and lactation

          Taking the drug is contraindicated during pregnancy and lactation.

          Reviews of Structum are not fundamentally different from reviews of other drugs of identical composition. Forums containing reviews of patients about Structum say that chondroitin are most effective as part of complex treatment, including procedures that increase blood circulation and therapeutic exercises. Reviews from doctors indicate that injectable drugs are more effective than other forms of release (tablets and capsules).

          Which is better: Artra or Structum?

          Based on a comparison of the compositions of the drugs, we can conclude that the effect of Artra is more complex, since it additionally contains glucosamine, which protects cartilage tissue from various damages. Otherwise, it is worth remembering that injectable drugs have greater bioavailability, and the treatment of joint pathology must be multicomponent.

          The price of Structum (60 capsules of 500 mg) in Russia varies from 980 to 1370 rubles.

          The price of Structum tablets in Ukraine averages 840 hryvnia and is even more variable depending on the region. Thus, buying the drug in the city of Kharkov will cost from 513 to 940 hryvnia. Injections of similar composition and action, as a rule, can be purchased below the price of Structum.

          List of the best chondroprotectors for the treatment of joint arthrosis: cost of drugs and patient reviews

          Chondroprotectors for arthrosis of the knee joint are prescribed to restore articular tissues through additional nutrition, supply of essential nutrients and vitamins. It is for this reason that they are the drugs of choice for the complex treatment of joint diseases.

          Medicines will help regenerate cartilage tissue

          Features of the therapeutic group

          Chondroprotectors have a cumulative effect. This means that the course of treatment with them is never short. Arthrosis develops in three stages. In the last of them, the joint is completely damaged, and its recovery is not possible even with the right course of therapy. This suggests that the use of chondroprotectors will be more effective the earlier they begin treatment.

          In medicine, two classifications of such drugs are officially accepted. The first is based on the time of introduction of drugs for use in the treatment of patients:

        27. 1st generation are biological preparations developed on the basis of extracts from the cartilage tissue of animals or fish (Alflutop, Rumalon).
        28. 2nd generation – monocomponent drugs for the restoration of cartilage tissue.
        29. 3rd generation - combination preparations that contain various dosages of chondroitin, glucosamine or hyaluronic acid. They can be supplemented with painkillers, anti-inflammatory, and vitamin components.
        30. The second way to classify chondroprotectors is based on their components:

        31. Products that are based on chondroitin sulfate (chondroitinsulfuric acid): Honsurid, Chondrolone, Chondroxide, Structum, Artron-chondrex, Mucosat.
        32. Preparations based on glucosamine: Dona, Artron flex, Elbona
        33. Joint fluid substitutes based on hyaluronic acid: Adant, Singial, Gialgan, Noltrex, Sinokrom.
        34. Medicines of biological origin with extracts of bone or cartilage tissue: Alflutop, Rumalon.
        35. Combined agents: Arteparon (mucopolysaccharides), glucosamine and chondroitin with an anti-inflammatory component (Teraflex Advance, Movex active), methylsulfonylmethane with chondroprotectors (Artron complex, Teraflex).
        36. Preparations with a complex composition (Formula-c).
        37. Arthrodar (a drug based on diacerein) – has anti-inflammatory, chondroprotective, analgesic effects.
        38. Rules for drug selection

          Only a specialist can prescribe chondroprotectors; which ones depend on the degree of arthrosis, as well as the severity of destructive changes in the joints. Thus, at the first stage it is possible to use tablet forms in combination with chondroprotective ointments. The second stage requires the use of injectable medications followed by a transition to long-term use of tablet forms.

          In the third stage of arthrosis of the knee joint or any other joints, the degenerative changes are so pronounced that there is no point in using chondroprotective tablets. It is better to use intra-articular administration of drugs with subsequent support of the result with injectable forms.

          Some experts distinguish the fourth stage of arthrosis (it is characterized by complete destruction of the joint, its immobilization). The use of chondroprotective medications at this stage will not bring any results, since, in fact, there is nothing left to restore.

          Chondroprotective drugs are always prescribed by a doctor. As a rule, a specialist is guided not by price or his own preferences, but by reviews of already healthy patients, as well as personally recorded dynamics of their treatment. Therefore, it is not worth replacing prescribed medications, despite the large number of analogues.

          Chondroitin normalizes metabolism in cartilage tissue

          The low effectiveness of generics is caused by a worse degree of purification of substances than the originals, and therefore increases the risk of developing unwanted side effects, allergic reactions, and a decrease in the effectiveness of therapy.

          Mechanism of action of drugs

          Chondroprotectors used at the beginning of the disease stop the process of joint destruction. For hip arthrosis, they help to completely restore hyaline cartilage if you start using them on time. Moreover, their effect is not selective, but complex, so the functioning of all joints improves at the same time, and the risk of arthrosis affecting healthy joint capsules is reduced.

          This effect of chondroprotectors is achieved thanks to their active components:

        39. Glucosamine – promotes the production of natural chondroitin by a person’s own cartilage tissue. When used, it relieves inflammation, destroys enzymes that destroy collagen, hyaluronic acid, and prevents the creation of free radicals that can damage cell membranes in osteoarthritis.
        40. Chondroitin - normalizes metabolism in cartilage tissue, promotes increased collagen production, stimulates the formation of chondrocytes (cartilage cells), hyaluronic acid, which is necessary for the natural production of collagen. In coxarthrosis and other forms of localized changes, chondroitin has an anti-inflammatory property, stimulates the formation of synovial fluid, which lubricates the surfaces of the joint, ensuring its mobility.
        41. In addition, the preparations often include hyaluronic acid, which is injected directly into the joint, activating collagen production, preventing damage to the articular surfaces, and slowing down destructive processes.

          General contraindications and indications for use

          Chondroprotectors are prescribed for diseases associated with degeneration of cartilage tissue, these include:

        42. Arthrosis (gonarthrosis, coxarthrosis, arthrosis of small joints).
        43. Periarthritis, arthritis (inflammation in the joints and periarticular tissues).
        44. Spondylosis (bone growths on the vertebrae).
        45. Osteochondrosis and joint injuries.
        46. Dystrophic changes in articular cartilage.
        47. The recovery period after surgery on the joints.
        48. There are few contraindications to the use of medications, including:

        49. Pregnancy, breastfeeding period.
        50. Allergy to the components of the drug.
        51. Chondroprotectors are prescribed with extreme caution if the patient has abnormalities in the gastrointestinal tract.

          Features of the use of various dosage forms

          Preparations for oral administration - Dona, Structum, Artra, Piaskledin, Teraflex, Formula-S. They begin to have the desired effect on the body only after 3 months, and after 6 months a sustainable effect is created.

          Only the attending physician can prescribe medications

          Injectable drugs:

          The effect of their use is noticeable faster, and the course of treatment is at least 10–20 injections. After completing the therapeutic course, maintenance therapy with tablet forms is recommended.

          Intra-articular fluid substitutes:

          These are preparations based on hyaluronic acid, which are injected directly into large joints, for example, for coxarthrosis. They replace intra-articular fluid, the production of which is reduced in arthrosis, and also have a chondroprotective effect. This is a completely medical procedure that cannot be performed independently. Such injections are rarely done in the hip joint area, and only under X-ray control, since it is difficult to insert the needle correctly “blindly”. Course – 3–5 procedures, repeated no earlier than after 6 months.

          Ointment chondroprotective drugs are used together with systemic forms, since the degree of penetration of the active substances through the skin barrier is too small for a sufficient therapeutic effect. Chondroprotective ointments (Chondroitin, Chondroxide, Artiflex) are recommended for maintenance therapy to quickly eliminate the acute inflammatory process. The best results are observed if ointments are used for physiotherapy (phonophoresis).

          Preparations based on hyaluronic acid are injected into large joints

          Rules for the use of chondroprotectors:

        52. Drugs in this group are available in capsules, solutions, gels, creams or ointments, and the correct dosage and method of use can only be selected by a doctor who has complete information about the condition of your body.
        53. Medicines may contain plant and animal components, to which each person may have a “personal” reaction. Therefore, you should not experiment by taking chondroprotectors without recommendations, otherwise there is a risk of developing even greater health problems.
        54. Treatment with chondroprotectors occurs only in long courses; they can be supplemented with agents that help the main drugs work better. In this case, their simultaneous use is mandatory.
        55. Using ointments or creams on your own is not effective. This is an adjuvant therapy method.

          Features of individual drugs, price comparison

          Dona (active glucosamine sulfate) – has anti-inflammatory properties, stimulates metabolic processes in arthrosis. The powder is diluted with water and taken before meals once a day for 6 weeks. Intramuscular administration of the drug - once a day every other day (4-6 weeks), the therapeutic effect becomes pronounced after two weeks of administration. Average price from 1000 rubles.

          Theraflex (active glucosamine and chondroitin sulfate) - take 2 capsules orally three times a day with a small amount of water after meals. Use is possible for arthrosis, osteochondrosis of the spine, traumatic damage to joints or bones. The course of treatment is from 3 weeks to 2 months. Cost from 500 rubles.

          Artra (active chondroitin sulfate and glucosamine hydrochloride) is a good chondroprotector used for osteochondrosis and arthrosis. The course of treatment begins with 1 tablet twice a day for 3–4 weeks, and then the dose is reduced to 1 tablet per day. Duration of treatment is at least 6 months. Price from 550 rubles.

          Glucosamine sulfate has anti-inflammatory properties

          Structum (a.v. chondroitin sulfate) – gelatin capsules of 500 mg are taken twice a day for six months. The cost is about 1000 rubles.

          Alflutop is a natural drug whose active ingredient is an extract of various species of Black Sea fish. The drug improves the metabolism of cartilage tissue and has anti-inflammatory properties. When large joints are affected (coxarthrosis), the drug is administered inside the joint, 1 ampoule per day, with a break between injections of 3-4 days. Course – 20 days. Cost from 1600 rubles.

          “Toad Stone” - available in the form of capsules for oral administration, as well as in the form of an ointment or balm with camelina (mushroom) oil - for topical use. At its core, it belongs to dietary supplements, because it contains toad grass, which contains chondroitin sulfate and glucosamine sulfate. Cost from 71 to 200 rubles.

          The table below displays the average prices of online pharmacies for chondroprotective agents.

          Structum chondroprotector: analogues of tablets, reviews of the medicine

          Structum belongs to dietary supplements that are used in the complex treatment of joint pathologies; the pharmacological group is chondroprotectors.

          These are substances that protect joint tissues from enzymes that destroy their structure, improve their nutrition and stimulate regeneration.

          Structum is produced by the French company Pier Fabre Medicament; in Russia the exclusive distributor is the pharmaceutical company SOTEX ZAO.

          Structum – effects on joints

          Structum stimulates the production of glycosaminoglycans, normalizes metabolism in fibrous and hyaline cartilaginous tissues and slows down degenerative changes in them. In addition, the tablets prevent the leaching of calcium from bone tissue and accelerate the growth and renewal of their cells.

          This effect helps reduce inflammation and pain in the joints, making them more mobile and flexible. The effect of the drug lasts for a long time even after the end of the course of treatment.

          Once in the body, Structum is 70% absorbed by the intestines and enters the joint tissues after approximately 4-5 hours. Chondroitin, the main active substance of the drug, tends to accumulate in the synovial fluid.

          The breakdown products of the drug are excreted through the kidneys.

          In what cases is Structum indicated?

          Indications for use are as follows:

        56. Primary arthrosis;
        57. Osteoarthritis of large joints;
        58. Osteoarthrosis of peripheral joints and spine.
        59. The drug is used for the treatment and prevention of these diseases.

          Typically, structum is well tolerated, can be combined with other medications and does not cause side effects. The drug is not prescribed in the following cases:

        60. The period of pregnancy and lactation.
        61. Children under 15 years of age due to the lack of research in this area.
        62. Poor blood clotting.
        63. Individual intolerance to any components of the drug.

        If structum causes allergic reactions, analogues of the drug are selected. If chondroprotectors are used in liquid form for injection, a side effect such as hemorrhages at the injection sites (small bruises) is possible.

        Release forms and chemical composition

        Structum is available in two pharmacological forms:

        Accordingly, I call the drug tablets or injections.

        Blue capsules in a gelatin shell are available in two dosages of chondroitin sulfate in powder form - 250 mg and 500 mg. Capsules with a dosage of 250 mg are placed in blisters of 15 pieces, and blisters are placed in cardboard packaging of 4 pieces. There are 60 capsules in total in one package.

        Capsules with a dosage of 500 mg are placed in blisters of 12 pieces, the package contains 5 blisters. Packages of 30 or 100 capsules are available for sale.

        Children over 15 years of age and adults are recommended to take 750 mg of the drug twice a day for the first three weeks of treatment. Then the single dosage is reduced to 500 mg. Capsules are intended for oral administration, do not chew them and are washed down with water. The first course of treatment lasts six months.

        Chondroprotectors accumulate in the body, their effect lasts from 3 to 5 months after the course of treatment is completed - this is when the result is assessed. How long the effect of the drug will last depends on the form of the disease and its stage at the time of treatment.

        Liquid for injection is administered intramuscularly. Initially, the drug is administered in 0.1 g doses. once every two days. If liquid chondroprotectors are well tolerated, the dosage is doubled from day 4. The course of treatment includes from 25 to 35 injections, it is repeated no earlier than six months later.

        Sometimes the drug can be prescribed to patients suffering from a tendency to bleeding and hemorrhage, if the degree of changes in the joint structures requires it and the general condition of the patient allows it.

        Treatment at home in this case is unacceptable; the patient must be admitted to a hospital and be under constant medical supervision.

        How much does it cost and where to buy structum

        Chondroprotectors of this type are available only with a doctor's prescription.

        A standard package of the drug for 60 capsules with a dosage of 250 mg costs from 370 rubles, a package for 60 capsules with a dosage of 500 mg costs from 950 rubles.

        Structum analogues are chondroprotectors that also contain chondroitin sulfate as the main component and are as close as possible to it in their action.

        Analogues containing only chondroitin sulfate: Artron Chondrex, Mucosat, Struknotin, Chondroxide, Chondrolone, Chondroflex, Arthrocels.

        Approximate analogues that additionally contain glucosamine: Atra and Theraflex.

        You can also find analogues among natural preparations containing extracts of plants, fish and animals: Aflutop (extract of cartilage tissue of marine fish), Rumalon (cartilage of large livestock), Piaskledin (extracts of avocado and soybean oils).

        Any analogues are selected and prescribed only by a doctor; it is not recommended to replace or supplement the course of treatment on your own.

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