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Rheumatoid arthritis and causes

19 Aug 18

All about rheumatoid arthritis

Rheumatoid arthritis primarily attacks the joints.

Arthritis is a chronic, systemic inflammatory disease that affects tissues and organs. Rheumatoid arthritis mainly attacks the joints. Although the causes are unknown, autoimmune diseases play a key role in its chronicity and progression. It is typical that the course of the pathology is long, with exacerbations and remissions.

Causes of the disease

Quite often, it is claimed that this disease affects older people. This statement is incorrect. The primary cause of the disease is rheumatism.

Rheumatoid arthritis affects many children aged 7 to 15 years. Rheumatic arthritis is caused by group A beta-hemolytic streptococcus. The pathology develops against the background of any infectious disease. Arthritis begins due to impaired immunity. The reasons are:

The difference between this disease and rheumatoid arthritis is its rapid development. Rheumatism is common throughout the world and is responsible for numerous cases of damage to the heart valves, which threatens the development of endomyocarditis or heart disease.

Chronic joint damage from rheumatoid arthritis occurs among all ages of the population.

Features of the clinical course of the disease

The clinical picture of relapse of rheumatism is complex and painful. The disease affects the joints and heart. The neurogenic factor is also of great importance in the occurrence of the disease. A mixed nature of symptoms is often found in the presence of rheumatoid arthritis.

Symptoms of rheumatic arthritis usually appear 2 weeks after an infection and subsequent hypothermia, fatigue or a stressful situation.

During an exacerbation, the patient's body temperature rises (fever). This condition is associated with inflammation and accumulation of synovial fluid in the joints. The destruction of cartilage tissue leads to joint deformation.

The primary symptom is severe pain due to the deformity. It has a “volatile”, growing character. Along with the attacks of pain that come several times a day with rheumatoid arthritis, symptoms of swelling of the joints and redness of the skin begin to bother the patient.

The deformity leads to impaired mobility, muscle atrophy and subsequent disability.

Nodules form under the skin and a burning sensation is felt. After the attack stops, joint deformation disappears. And the disease continues to affect other areas, spreading the source of inflammation day after day.

During the period of remission, the body temperature decreases slightly, the person sweats a lot, which is characteristic of rheumatic syndrome.

This disease affects the heart. Patients complain of unpleasant pain. During the examination, the doctor may hear noises. The disease affects the inner and outer lining of the heart.

Laboratory tests to detect the disease

Early diagnosis is critical. Because the manifestations of rheumatic syndrome are so varied that early heart complications may occur.

Blood test results will give you a clearer picture of the disease's progression

To determine the activity of the inflammatory process, it is necessary to conduct a series of laboratory tests. One of the first tests is to donate blood to determine the erythrocyte sedimentation rate. Usually they indicate an inflammatory process. During the period of exacerbation of rheumatoid arthritis, the erythrocyte sedimentation rate rises to 20–30 mm/h. If the joints are already attacked, ESR values ​​range from 40 to 60 mm/h. Also, with the acute nature of the disease, an increase in the number of leukocytes is observed.

A biochemical blood test will give a more complete picture of the course of the disease. But an increased level of fibrinogen does not always indicate the presence of rheumatic arthritis. The dominant protein of the acute phase of inflammation, which takes part in the body's universal immune response to present damage, and platelets also increase.

Blood tests are performed in conjunction with rheumatoid factor testing.

Imaging tests for diagnosis

To confirm the diagnosis, an imaging test is sometimes required. X-ray diagnosis is not necessary in most cases. In the picture you can only see the presence of deformation.

For rheumatic syndrome, rheumatologists recommend the following studies:

  • electromyogram;
  • plantogram;
  • skin thermography;
  • arthroscopy;
  • joint scintigraphy;
  • radiological examination.
  • These examinations will help rheumatologists and radiologists make the correct diagnosis, eliminating some pseudo-negative or pseudo-positive aspects.

    Detection of heart problems requires an electrocardiogram and ultrasound examination.

    Drug treatment of acute attacks

    To eliminate residual substances after a streptococcal infection, it is necessary to take Phenoxymethylpenicillin or Benzathine penicillin orally for 10 days.

    Treatment for rheumatoid arthritis then focuses on relieving symptoms. Bed rest is important because it reduces joint pain and reduces cardiac strain.

    The duration of bed rest depends on the indicators. Inflammatory markers (leukocytes, platelets, ESR, temperature) must be reduced to a certain level.

    Prolonged bed rest, especially in children or adolescents, creates problems of boredom and depression that need to be addressed.

    Some patients, especially in early adolescence, develop a fulminant form of heart failure with severe mitral regurgitation, and sometimes concomitant aortic regurgitation. If heart failure does not respond to drug treatment, valve replacement is required.

    It is worth noting that there are no radical methods to cure rheumatic arthritis.

    Treatment of polyarthritis with non-steroidal anti-inflammatory drugs

    Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics should be used as symptomatic therapy only in combination with DMARDs. These agents have no effect on stopping the progression of the disease.

    If you treat rheumatic arthritis with NSAIDs for a long time, you can get gastritis, peptic ulcers, hypertension, and kidney failure.

    Most of them act as analgesics. List of NSAIDs prescribed for the disease:

    The most commonly prescribed enteric form of Aspirin is for arthritis; the treatment relieves the symptoms of arthritis quickly and efficiently. Within 24 hours, the medicine helps confirm the diagnosis.

    If Aspirin is used incorrectly, a toxic effect may occur:

    In addition, it causes tinnitus and temporary deafness if its concentration in the blood exceeds the permissible limit. Aspirin should be continued until the ESR drops to the desired level.

    If intoxication occurs, consult a doctor for advice to change the drug.

    Selective COX-2 inhibitors, such as Celecoxib and Rofecoxib, have a low risk of gastrointestinal erosions and ulcers. A disadvantage of the new agents is the increased risk of cardiovascular complications for patients taking these drugs.

    The role of glucocorticoids and corticosteroids in the treatment of the disease

    Glucocorticosteroids (GCS) are used to suppress inflammation and preserve joints. They are often prescribed in the initial stages of development or during the next outbreak as a temporary aid and in gaining control of the disease.

    Because of their long-term side effects, corticosteroids should not be taken continuously. In prolonged forms, they are used for intra-articular injections. GCS in high doses is prescribed to treat a life-threatening disease, for example, rheumatoid vasculitis. They are allowed to be used to control the development of pathology during pregnancy, when most other drugs are contraindicated.

    Corticosteroids produce more rapid symptom relief than aspirin and other NSAIDs. There is no evidence that long-term use of steroids is beneficial. In the acute phase of rheumatic arthritis, Prednisolone is prescribed. The drug should be taken until the ESR returns to normal.

    Rheumatoid arthritis

    Rheumatoid arthritis is an infectious-allergic disease, which is one of the symptoms of rheumatism or Sokolsky-Buyo disease. The factors causing the development of this disease are not fully understood to date.

    Let's look at what rheumatoid arthritis is.

    This diagnosis is made for a patient with acute articular syndrome caused by rheumatic fever.

    Most often, rheumatoid arthritis affects young people between 6 and 16 years of age. Elderly people suffer from a similar disease in exceptional cases.

    The rheumatic process affects these joints:

    As a rule, rheumatoid arthritis develops against the background of infection of the body with a hemolytic streptococcal bacterium, which also provokes the development of infectious diseases of the upper respiratory tract. Approximately 14-28 days after suffering from an infectious disease, rheumatic lesions begin, spreading to the joints of the musculoskeletal system, to the heart and to other important organs.

    The following factors can cause the development of rheumatic joint damage:

    1. Infectious diseases of the upper respiratory tract:
    2. Angina;
    3. Pharyngitis;
    4. Tonsillitis;
    5. Sinusitis.
    6. Disrupted activity of the body's defense system;
    7. Acute allergic reaction;
    8. External influencing factors:
      • Hypothermia;
      • Severe stress;
      • Overwork.
      • Distinctive characteristic

        According to experts, rheumatoid arthritis and rheumatoid arthritis are two completely different types of arthritic lesions of the connective tissue of the human musculoskeletal system. Only the symptomatic manifestations of articular syndrome are similar.

        Unlike rheumatic joint disease, RA is a multistructural lesion and occurs with greater intensity.

        The distinguishing features of these diseases are the following:

      • Speed ​​of disease development:
      • Rheumatoid arthritis develops rapidly;
      • RA is chronic and slowly progressive.
      • Spread of the disease:
      • Rheumatic disease affects the heart valve, which threatens the development of endomyocarditis or heart disease;
      • Rheumatoid arthritis is accompanied by deformation of bone structures, ankylosis and erosion.
      • Laboratory indicators:
      • In rheumatoid arthritis, the level of ASH and ASL-O titers is increased;
      • In RA, an increased level of CCP antibodies is observed in the blood and rheumatoid factor is present in 80% of cases.
      • Medicine knows more than 100 types of arthritic diseases. Therefore, only a qualified rheumatologist can diagnose rheumatoid arthritis or rheumatoid arthritis.

        Rheumatoid disease of the body is accompanied by these symptoms:

      • Joint syndrome;
      • Heart dysfunction;
      • Nervous system disorder;
      • Mixed symptoms of the disease.
      • The initial stage of the disease is characterized by an acute course. Symptoms of rheumatoid arthritis appear 2-4 weeks after the infectious disease.

        Rheumatoid arthritis symptoms:

      • Intense increasing pain in the area of ​​large joints;
      • The pain syndrome becomes especially acute at night; when moving and putting stress on the affected joint, the patient feels a sharp pain;
      • The inflammatory process can affect one or more joints in a symmetrical manner;
      • Fluctuation is observed in the area of ​​large joints, which indicates serous effusion;
      • Soft periarticular tissues swell;
      • The skin around the affected joint becomes red and hypersensitive to touch;
      • The mobility of the joint is partially or completely lost;
      • Both local and general temperatures may rise to high levels;
      • Sweating increases;
      • Decreased general health;
      • Dyspnea;
      • Pain in the chest area.
      • Diagnostic procedures

        Rheumatoid arthritis symptoms and treatment are determined by the attending physician, who first conducts a course of special laboratory tests.

        To determine the disease, the doctor uses the following diagnostic methods:

      • History taking:
      • History of the development of this disease;
      • Allergic reactions;
      • Previous illnesses.
      • External examination of the patient;
      • Biochemical blood test to determine:
  • ESR (in rheumatoid arthritis, the erythrocyte sedimentation rate is increased);
  • The level of the seromucoid component (increased);
  • Blood content of immunoglobulin, fibrinogen, leukocytes.
  • Analysis of synovial fluid for research:
  • Mononuclear cell level;
  • Fibrin.
    1. Analysis for the presence of streptococcus bacteria in the body;
    2. Ultrasound;
    3. X-ray images;
    4. ECG (electrocardiogram helps monitor changes in heart rhythm).
    5. Rheumatoid arthritis treatment:

    6. Drug therapy;
    7. Traditional medicine;
    8. Physiotherapeutic activities;
    9. Diet food;
    10. Physical therapy course;
    11. Spa treatment;
    12. Methods of disease prevention.
    13. The initial stage of therapy is the most important, because the further outcome of the entire treatment process will depend on it. Treatment takes place in a hospital during the first 10-14 days after the onset of acute symptoms of the disease.

      If the symptoms are less severe, the patient can stay at home, but he must be provided with complete rest.

      An intensive method of treating rheumatoid arthritis is drug therapy.

      Drug treatment

      For the treatment of rheumatic lesions, it is recommended to take these groups of medications:

    14. Antirheumatic drugs (act directly on the disease itself, stopping foci of inflammation, for example, Voltaren):
    15. NSAIDs (non-steroidal anti-inflammatory drugs are used for symptomatic treatment - relieve pain, inflammation, reduce fever):
    16. Acetylsalicylic acid (aspirin);
    17. Indomethacin;
    18. Diclofenac.
    19. Corticosteroid drugs (used for intra-articular administration when the disease is severe, and also if NSAIDs are ineffective);
    20. Penicillin drugs, for example, bicillin-5 (to eliminate streptococcal bacteria);
    21. Antibiotics;
    22. Vitamin complexes and preparations to normalize metabolic processes.
    23. NSAIDs and corticosteroids are active, potent drugs that have a negative effect on the gastrointestinal tract. Considering the high likelihood of developing side effects when children use these drugs, experts prescribe minimum dosages of medications for use.

      Experts say that the success of rapid therapy largely depends on the patient’s diet. Therefore, in order to speed up the recovery process and transfer the acute stage of the disease into a state of remission, it is necessary to adhere to a certain diet.

      During treatment, it is necessary to completely exclude or, if possible, reduce the amount of salt consumed from your diet. You can use this spice 10-20 days after complete recovery.

      Prohibited Products

      If you have rheumatoid arthritis, you should avoid eating the following foods:

    24. Mushrooms;
    25. Beans, peas, beans;
    26. Sorrel;
    27. Spinach;
    28. Broths from poultry, pork, fish;
    29. Fatty, smoked, fried foods;
    30. Hot spices;
    31. Confectionery with cream, chocolate;
    32. Sugar;
    33. Grape.
    34. Authorized Products

      The menu of a sick person should include these products:

      You can learn everything about rheumatoid arthritis from the video presented:

      The most effective way to prevent the development of rheumatoid arthritis is to quickly treat infectious diseases of the body or prevent them. Therefore, it is necessary to take care of the health of your children, especially during seasonal exacerbations of diseases such as influenza and sore throat.

      To prevent infectious diseases, use these methods:

    35. Enriching the body with vitamins (consume more fruits or ready-made vitamins from the pharmacy);
    36. Avoid crowded places;
    37. Use a gargle;
    38. Wash your hands thoroughly after going outside and touching people or objects;
    39. Systematically take a course of special antibiotics to prevent infection (consult your doctor first).
    40. Rheumatoid arthritis in a child - causes, symptoms, diagnosis and treatment

      Children are more susceptible to this pathology. In adulthood, relapses of the disease are more common than primary cases of acute rheumatic fever.

      Rheumatoid arthritis in a child is one of the symptoms of rheumatism (acute rheumatic fever). This is a systemic inflammatory disease of connective tissue that occurs after an acute infectious process caused by group A β-hemolytic streptococcus.

      As a rule, children aged 7 to 15 years are most susceptible to the disease.

      The development of the disease in a child is facilitated by the individual characteristics of the immune system and the tendency to frequently develop infectious diseases (especially in children attending kindergarten or primary school). Much attention is paid to hereditary predisposition.

      Acute rheumatic fever occurs two to three weeks after a streptococcal infection. In young children it can be scarlet fever, in an older child it can be sore throat, pharyngitis, pyelonephritis and other diseases. The mechanism of development of rheumatism is associated with the action of pathogen toxins on the body and the emergence of antibodies against its own tissues. As a result, serous-fibrinous synovitis occurs in the joint without damage to the cartilage and other structures. Therefore, rheumatoid arthritis does not leave behind changes in the joint.

      There are the following phases of rheumatic fever:

      There are 3 degrees of disease activity: I, II and III.

      Course of rheumatic fever

    41. acute (bright symptoms of the disease, the course of the process - up to 3 months);
    42. subacute (slow onset of the disease, less pronounced clinical and laboratory manifestations and duration up to 6 months);
    43. protracted (moderate symptoms, resistance to therapy and duration of more than 6 months);
    44. continuously recurrent (wavy course);
    45. latent (no symptoms).
    46. Symptoms of rheumatism in children

      In children, the disease manifests itself as high fever (38-39° C and above) and intoxication (weakness, headache, “aches” in muscles and joints), against which the following characteristic symptoms of rheumatism occur:

    47. arthritis primarily affecting large joints (knees, elbows, ankles, wrists);
    48. symmetry of joint damage (for example, arthritis occurs in both knee joints);
    49. “volatility” of the pathological process (for example, today one joint is bothered, tomorrow – another);
    50. increase in size of joints and their deformation;
    51. the skin over the inflamed joint becomes red and hot to the touch;
    52. movements are limited and severely painful.
    53. Arthritis with rheumatism does not last long - from several days to a week, after which mobility in the joint is completely restored, without leaving behind any pathological changes. Persistent deformities and contractures are not typical.

      In some cases, the disease may manifest itself only as arthritis of one joint (monoarthritis) or even arthralgia (joint pain).

      Other manifestations of acute rheumatic fever include:

    54. Carditis (inflammation of the lining of the heart) occurs in most children (85% of cases) during the first attack of rheumatism. All three cardiac membranes (pericardium, myocardium and endocardium with the occurrence of pericarditis, myocarditis and endocarditis, respectively) can be affected - together or separately. The disease can be severe and be accompanied by symptoms such as shortness of breath, palpitations, swelling and other signs of circulatory failure. If the endocardium is involved in the inflammatory process, then carditis can result in the formation of heart disease.
    55. Chorea. It occurs most often as a manifestation of the disease in teenage girls. Its symptoms are: mood swings, decreased muscle tone, loss of coordination of movements, hyperkinesis (random muscle twitching). Chorea usually lasts 1.5-2 months, completely disappearing after 3 months.
    56. Skin damage. A characteristic manifestation of the disease is the appearance on the skin of the torso, less often on the face, neck and limbs of anular erythema (thin pale pink ring-shaped rashes that disappear with pressure). Subcutaneous rheumatic nodules may also be detected, appearing in the active phase of the disease and persisting for up to 1-2 months. They are round, painless, inactive, up to 1-2 mm in size, usually located above the joints.
    57. With rheumatic fever, damage to internal organs is possible: lungs, liver, eyes, kidneys, thyroid gland, but at present this course of the disease is extremely rare.

      The features of modern rheumatic fever are the following: the symptoms of the disease are less pronounced, the severity of carditis is moderate or minimal, and heart defects are rarely formed. Thus, the prognosis of the disease has improved somewhat.

      Diagnosis of rheumatism in a child

      Diagnosis of any type of arthritis in a child, including rheumatism, should be carried out by a qualified specialist.

      To identify the disease you need:

    58. Medical examination. The specialist determines the presence and nature of arthritis, as well as other specific symptoms of rheumatic fever. Detection of any two of the following signs in a child: polyarthritis, carditis, chorea, anular erythema, rheumatic nodules, is sufficient to diagnose rheumatic fever. These symptoms are called the “major” Kissel-Jones-Nesterov diagnostic criteria. In addition to them, there are “minor” criteria: fever, data from laboratory and instrumental studies, previous streptococcal infection.
    59. Laboratory research methods:
    60. general blood test: increased number of leukocytes, shift of the formula “to the left” (increased number of band forms), accelerated ESR, possible anemia;
    61. biochemical blood test: “shifts” in protein fractions (dysproteinemia), an increase in C-reactive protein and seromucoid;
    62. special studies: rheumatic fever is characterized by an increase in ASLO (antistreptolysin O), ASH (antistreptohyaluronidase) and ASA (antistreptokinase), an increase in the amount of immunoglobulins of classes A, M, G, CIC (circulating immune complexes), anticardiac antibodies.
    63. Instrumental research methods:
    64. X-ray of the affected joints. Since rheumatoid arthritis has a benign course, and no pathological changes occur in the inflamed joint, this study is not informative. But x-rays are still necessary for differential diagnosis with other types of arthritis. The same applies to methods such as computed tomography and magnetic resonance imaging (CT and MRI, respectively).
    65. If rheumatic fever is confirmed, an ECG and ultrasound of the heart (echocardiography) are required to exclude carditis (inflammation of the lining of the heart). Other studies may be performed according to indications.
    66. Treatment of rheumatoid arthritis (rheumatic fever):

      Treatment of rheumatism is long-term, complex, staged and continuous.

      Therapy in children is carried out only under the supervision of a specialist. Many medications are prohibited for use in children or can only be used in limited quantities, so there is no point in experimenting.

    67. General activities:
    68. bed rest during the entire period of fever, and then for at least another month after the temperature normalizes;
    69. diet;
    70. physiotherapy.
    71. Drug therapy:
    72. antibacterial drugs to combat β-hemolytic streptococcus (penicillin, amoxicillin, macrolides, cephalosporins and others);
    73. non-steroidal anti-inflammatory drugs - to relieve pain and relieve inflammation in the joints (diclofenac, indomethacin and others);
    74. hormonal drugs - usually used when non-steroidal drugs (prednisolone, hydrocortisone) are ineffective;
    75. quinoline drugs (delagil, plaquenil) - for prolonged periods.
    76. Stages of therapy

    77. in a specialized department of a hospital;
    78. in a cardio-rheumatological sanatorium;
    79. dispensary observation in the clinic.
    80. Prognosis of rheumatic fever

      Rheumatoid arthritis always has a favorable prognosis.

      As a rule, even in the absence of adequate and timely treatment, the disease still passes without a trace, never leading to permanent changes in the joints and disability.

      With rheumatism, the prognosis is largely determined by the presence or absence of heart damage.

      Carditis can lead to permanent heart defects and circulatory failure, which requires drug therapy or even surgery.

      Rheumatoid arthritis. Description, clinic, classification

      2018-04-17 19:26 What is knee arthritis: causes of pathology, statistics Rheumatoid arthritis is a systemic disease of connective tissue.

      rheumatoid arthritis

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      Rheumatoid arthritis symptoms

      Some diseases are caused by a hereditary predisposition, but some predisposing factors are required to activate the pathological process. One such disease is rheumatoid arthritis.

      Rheumatoid arthritis – what is it?

      IT IS IMPORTANT TO KNOW! The only remedy for JOINT PAIN, arthritis, arthrosis, osteochondrosis and other diseases of the musculoskeletal system, recommended by doctors! Read more.

      Rheumatoid arthritis is a connective tissue disease that develops in individuals with a genetic predisposition after exposure to certain provoking factors. The disease most often occurs in women over 40 years of age and is characterized by the development of irreversible degenerative and inflammatory processes in small joints, as a result of which their normal functioning is disrupted.

      Rheumatoid arthritis can be seropositive (occurs in most cases) or seronegative. In the first case, rheumatoid factor is present in the patient’s blood, and the disease develops gradually.

      When seronegative RA is detected, rheumatoid factor is absent, the clinical picture of the disease develops quickly, beginning with inflammation of the joints of the wrist or knee joint.

      According to ICD 10, rheumatoid arthritis is designated M05 (seropositive), M06 (seronegative) and M08 (juvenile) - a detailed table of codes is at the end of the article.

      Rheumatoid arthritis is often confused with arthrosis or regular arthritis. These are completely different diseases, although in both cases there is damage to the joints, the difference between rheumatoid arthritis and arthritis can be seen in the table:

      The development of rheumatoid arthritis can be caused by numerous factors, the most common of which are:

    81. Heredity - in patients who have had cases of this disease in their family, genes are present in the body, and the immune system begins to produce antibodies against them;
    82. Infectious diseases - rubella, herpes simplex, Epstein-Barr virus, hepatitis and others. These diseases most often provoke the further development of rheumatoid arthritis.
    83. The first signs of rheumatoid arthritis

      It is not difficult to completely restore JOINTS! The most important thing is to rub this into the sore spot 2-3 times a day.

      Most often, rheumatoid arthritis develops in the cold season; the provoking factor can be hypothermia, viral or infectious diseases, surgery, or food allergies.

      At the initial stage of development, the disease may not manifest itself in a pronounced clinical manner; a patient with rheumatoid arthritis is concerned about general symptoms:

    84. Increased sweating;
    85. Muscle weakness even at rest;
    86. Minor changes in body temperature not caused by a viral infection;
    87. Fast fatiguability;
    88. Losing weight.
    89. As the pathological process progresses, pain in the joint area is added, which is aching, periodic, and constant.

      After the slightest physical exertion or during treatment with anti-inflammatory drugs, the pain syndrome intensifies, and symmetrical damage to small joints appears.

      The inflammatory process in rheumatoid arthritis of the joints is accompanied by fever, lethargy of the patient, general weakness, and muscle pain.

      A characteristic sign of rheumatoid arthritis in the hands is the appearance of stiffness in the morning, mainly after sleep. The patient cannot perform the usual actions with his fingers; they seem to not obey.

      Attempts to move the fingers are accompanied by increased pain, which goes away after about 40 minutes. Morning stiffness is due to the fact that during the night pathological fluid accumulates in the area of ​​joints affected by degenerative and inflammatory processes, which prevents full movements.

      As the pathological process progresses, the patient develops visible deformations of the limbs - “walrus flippers”, spindle-shaped fingers and a swan neck. The first signs of rheumatoid arthritis include other joint lesions:

    90. Impairment and sharp limitation of mobility of the elbow and radioulnar joints;
    91. Damage to the shoulder joint - increased local body temperature, hyperemia of the skin over the inflamed joint, pain, limited mobility, gradual muscle atrophy;
    92. Damage to the joints of the foot, namely deformation of the toes, sharp pain during exercise (walking, running), inability to choose shoes, impaired gait and stability;
    93. Inflammation and gradual deformation of the ankle joint;
    94. Damage to the knee joint, limitation of its mobility;
    95. Deformation of the joints of the spinal column (usually in the last stages of the disease);
    96. Damage to the joint of the first cervical vertebra of the atlas, as a result of which the mobility of the neck is sharply impaired, severe pain in the back of the head appears, and a crunching sound occurs when trying to turn the head to the side.
    97. In addition to joint lesions, signs of rheumatoid arthritis are other manifestations:

    98. The appearance under the skin of so-called rheumatoid nodules;
    99. Excessive dryness and flaking of the skin;
    100. Small hemorrhages under the skin (ecchymoses and petechiae);
    101. Increased brittleness of nails;
    102. Necrosis of tissues of the periungual bed;
    103. Impaired function of the muscles that are attached to the joints affected by the inflammatory and degenerative process, a decrease in their tone, gradual atrophy;
    104. Minor disturbances in the functioning of the gastrointestinal tract - bloating, flatulence, loss of appetite;
    105. The development of diseases of the respiratory system - dry pleurisy, damage to lung tissue;
    106. Diseases of the cardiovascular system – endocarditis, pericarditis, myocarditis;
    107. Severe damage to the glomeruli of the kidneys, development of glomerulonephritis.
    108. How to distinguish rheumatoid arthritis from rheumatic arthritis?

      Quite often, rheumatoid and rheumatoid arthritis are perceived as one disease, as they have very similar symptoms. But the pathologies have many differences, which are associated with the development mechanism and negative changes that affect the joints. In order to understand exactly what disorders occur in the joint structure, you need to learn to distinguish diseases from each other.

      Rheumatoid arthritis has a chronic course with progressive development of the pathological condition. Refers to a severe form of rheumatic changes in ossicular cartilage tissue. During the period of exacerbation, it manifests itself with severe symptoms with a rapid increase in pain. Thanks to therapeutic measures, the disease goes into remission in a short time. With the active development of the disease, a number of serious complications are observed that lead to irreparable deformations of bone and muscle tissue.

      Rheumatoid arthritis initially affects small joints. As it develops, large articular joints are drawn into the pathological process.

      Rheumatoid arthritis is characterized by inflammatory processes in osteochondral tissue. Refers to common diseases, especially among women. It has no age restrictions, so it occurs even in preschool children. It mainly affects small joints such as the hands and feet. Less commonly, rheumatism affects the ankle and elbow joint.

      Differences between rheumatoid and rheumatoid arthritis

      The root cause of the development of rheumatoid arthritis has not been established. The factor that acts as a trigger for the formation of pathology is considered to be autoimmune disorders. The disease develops slowly. At the initial stages it has a hidden clinical picture. The disease causes disruption of cell regeneration.

      The cause of the development of rheumatism is considered to be a previous streptococcal infection, which affects the body during a sore throat or other bacterial infection. It differs from rheumatoid arthritis in that it begins acutely and progresses quickly. Rheumatic disease affects the cardiovascular system and can cause heart valve disease. There is a big difference between the two ailments, which can be seen in the comparative table.

      As a rule, rheumatism develops as a complication of the active effects of streptococcal infection on the human body. The first signs of the disease appear a few weeks after suffering from tonsillitis, tonsillitis, and sinusitis. The development of rheumatoid arthritis is influenced by autoimmune changes in the body, which cause dysfunction of the immune system. There are also a number of factors that provoke the activity of diseases:

      The rheumatic form of the disease is characterized by an acute onset, which is accompanied by an increase in body temperature, pain in the affected joint, swelling and hyperemia of the periarticular soft tissues. Due to intoxication of the body, the patient’s health rapidly deteriorates, weakness, headaches and nausea are noted. The mobility of the diseased joint is impaired. Rheumatoid arthritis is characterized by moderate pain upon awakening, a feeling of stiffness, low-grade fever and slight weakness.

      As the disease develops, the pathology spreads to the muscles and leads to arthralgia and myalgia.

      Therapeutic measures

      Treatment of rheumatism involves taking non-steroidal anti-inflammatory drugs, as well as antibacterial agents. For severe pain, corticosteroids are used. The rheumatoid form of the disease is treated with radioactive drugs, immunosuppressants and corticosteroids. In severe cases, orthopedic correction is indicated, which is performed surgically. To treat all forms of the disease, exercise therapy, physiotherapy and balneological procedures are used, which help improve blood circulation, reduce pain and restore mobility of the affected joint. Particular attention is paid to dietary nutrition with minimal consumption of animal fats.

      Rheumatoid arthritis: treatment and prevention

      Until now, the real causes of rheumatoid arthritis are not understood. The damage to connective tissue is autoimmune in nature, and small joints are more often damaged. People over 35 years of age are more prone to this disease. Researchers have also identified a genetic predisposition to this disease. But it is difficult to say what exactly causes such an immune reaction in the body.

      Causes of rheumatoid arthritis

      What is happening in the body, what is the failure of the immune system? Defense cells designed to fight off invading bacteria and infections lose their bearings and begin to destroy their own healthy cells, especially joint cells. This can cause an infectious disease or infection. After infections, viruses and microbes may remain in the joints. Less commonly, rheumatoid arthritis is triggered by injury or hypothermia.

      In many patients, rheumatoid arthritis developed after severe shock. This is especially true for a certain type of character. Numerous studies have also been conducted in this area and it has been found that women who hide their emotions and irritation are more susceptible to this disease. It is precisely the superimposition of stress on such excessive emotional restraint that causes rheumatism. The hormonal system is very reactive to negative emotions.

      Immune system cells attack joints methodically, sometimes for years. The synovial membrane of the joint is especially affected, mainly the part that is adjacent to the cartilage. The membrane swells, grows, and sometimes grows into cartilage or even bone. All this, if not properly treated, destroys the structure of the joint.

      Symptoms of rheumatoid arthritis

      Rheumatoid arthritis appears gradually. At first it’s just fatigue, weakness, appetite may decrease, the patient begins to lose weight, the temperature rises, and the lymph nodes enlarge. The joints swell, hurt, and sometimes turn red. In addition to the joints themselves, the ligaments and muscles located around them become inflamed.

      Rheumatoid arthritis is characterized by symmetry, i.e. if the right knee joint is affected, then the left one is also affected; the left elbow joint becomes ill, which means that the right one also begins to hurt. All this is accompanied by morning joint stiffness. Each type of joint has its own distinctive symptoms:

      • hand – deformation like “boutonniere”, “swan neck”, “hands with a lorgnette”;
      • foot – deformation of one toe;
      • knee – Baker's cyst (elastic formation in the popliteal fossa), flexion deformity;
      • cervical spine – subluxation of the atlantoaxial joint.
      • The formation of rheumatoid nodules is typical - dense subcutaneous formations 2-3 cm in diameter. Kidney function is impaired, the number of platelets decreases, and iron metabolism slows down, which leads to anemia. In general, the symptoms of rheumatoid arthritis are not hidden and are easily recognizable in the early stages. It begins with swelling and inflammation of the index and middle fingers, especially in the area of ​​the bones, which protrude when the fist is clenched. Sometimes the wrist joints are the first to be affected.

        At the same time, the joints of the toes become inflamed - it hurts when pressing on the pads of the toes from below. As the disease progresses and blood supply deteriorates, the skin on the wrists turns pale, becomes dry and thin. When a Baker's cyst grows in the knee joint, fluid can rupture the capsule and spread into the soft tissue along the back of the leg.

        Diagnosis of rheumatoid arthritis

        After a careful examination and detailed questioning of the patient, the doctor refers the patient to a general and biochemical blood test, which identifies the factors of rheumatoid disease. These tests for rheumatoid arthritis also detect signs of inflammation. Blood shows the presence of anemia, an increase in ESR (erythrocyte sedimentation rate), and the presence of an inflammatory process occurring in the body. The presence of rheumatoid factor is shown by the result of a blood test taken from a vein.

        how to diagnose rheumatoid arthritis

        However, the diagnosis is made in aggregate. For example, rheumatoid factor may not be a clear indicator of rheumatoid arthritis, just as its absence does not mean that this disease does not exist in the body. To determine the severity of the disease, an x-ray of the hands and feet is taken, which shows a narrowing of the joint space and erosion of the bones of the metacarpophalangeal joints. In severe forms, x-rays show fusion of the bones with each other, which kills the mobility of the joint.

        If the test for the presence of rheumatoid factor is negative, but the disease is still suspected, citrulline antibodies are detected. They are not normally present in the blood. At the very initial stage of the disease, when an x-ray may not show the problem, a magnetic resonance examination can cope with this. Sometimes it makes sense to test the synovial fluid of the affected joint. If there is inflammation, it will be cloudy, not viscous enough and with an increased presence of protein.

        The task before the doctor is not an easy one when it comes to rheumatoid arthritis: causes, diagnosis, treatment - all this is processed in a complex. To make this diagnosis, at least 4 of the following criteria must be present within 6 weeks:

      • morning stiffness,
      • inflammation of 3 or more joints with the formation of excess fluid,
      • inflammation of the metacarpophalangeal, interphalangeal and wrist joints,
      • presence of rheumatoid nodes,
      • symmetrical inflammation of the joints of one group,
      • presence of rheumatoid factor in the blood,
      • obvious picture on x-rays.
      • view of the hand with rheumatoid arthritis

        Pediatric rheumatoid arthritis

        Juvenile rheumatoid arthritis can also develop in children under 16 years of age. These are the consequences of an infectious disease, injury or hypothermia. This disease can last for several years. The main symptom is joint pain.

        Damage to one or more joints is called oligoarthritis. Among schoolchildren, mostly boys suffer from this disease. A form of juvenile rheumatoid arthritis that affects many joints is called polyarthritis. Polyarthritis without the presence of rheumatoid factor – seronegative – affects more girls. Polyarthritis with identified rheumatoid factor – seropositive. Girls suffer from this form during puberty.

        Systemic juvenile rheumatoid arthritis begins with fever, skin rash, painful swelling of the joints, enlarged lymph nodes, liver, and spleen. The form of the disease is quite severe: physical development is inhibited, growth slows down, and some segments of the skeleton do not develop. Such children are especially susceptible to infections. On the face there is damage to the joints.

        The youngest patients may not even experience pain. Therefore, parents discover the problem belatedly, noting dysfunction. It is necessary to pay attention to morning stiffness. Treatment of this disease is usually carried out in a hospital. Later, gymnastics and physiotherapy are prescribed.

        Consequences of rheumatoid arthritis

        People with rheumatoid arthritis who stop taking cholesterol-lowering medications have an increased risk of death. Refusal of statins increases the possibility of developing cardiovascular pathology. Less often, such patients die from myocardial infarction or stroke. This concerns heart complications. Directly, rheumatoid arthritis causes inflammation to damage and destroy the cartilage and tissue around the joint. This limits movement and can lead to disability.

        If, when diagnosed with rheumatoid arthritis, treatment prescribes the use of medications, then this must be strictly followed, just like giving up smoking, doing exercises, and monitoring your weight. In fact, the risk of death with rheumatoid arthritis is not so great, but by starting this disease, the chance of causing disability increases significantly.

        Prevention and treatment of rheumatoid arthritis

        Rheumatoid arthritis cannot be completely cured. All methods are aimed at reducing inflammation, eliminating pain, improving or returning joint function. Immunosuppressants put the patient into remission. Much attention is paid to physical therapy. As a rule, treatment includes drugs of three groups:

      • non-steroidal anti-inflammatory drugs with high anti-inflammatory and analgesic activity. It is impossible to combine several non-steroidal drugs, otherwise the risk of side effects increases;
      • basic drugs - to increase the effectiveness of their slow action, a high dose of hormones is used;
      • hormones themselves - they are sometimes used as supportive anti-inflammatory or local therapy. These can be ointments, creams, gels.
      • In the treatment of rheumatoid arthritis, much attention is paid to the prevention of osteoporosis, when the calcium balance of absorption into the intestines and excretion from the body is disturbed. In this case, a diet with increased calcium intake (nuts, dairy products) is used. Vitamin D should be included.

        At an early stage, laser therapy can be used for a course of up to 15 sessions. To eliminate pain and spasms, you can undergo a course of cryotherapy (cold treatment). To improve tissue nutrition and eliminate inflammatory processes in the early stages, ultraviolet irradiation is recommended. For more serious changes in the joints, pulsed currents and magnetic therapy are prescribed. It is recommended to carry out spa treatment annually:

      • radioactive baths,
      • hydrogen sulfide baths,
      • mud applications.
      • When the exacerbation of arthritis passes and blood counts are normal, you can undergo a course of massage and physiotherapy. The fact is that they are very useful for arthrosis, but for arthritis they can increase inflammation. Sometimes radiotherapy is used to enhance the effect of basic drugs. The final stage is therapeutic exercises. The main goal of all these measures is to prolong remission, improve quality of life, prevent irreversible changes, and reduce symptoms of the disease.

        Categories : Prevention

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