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Drugs for the treatment of arthritis and arthrosis

29 Jul 18

Effective drugs for the treatment of joint arthritis

Arthritis is one of the many common diseases. For a long time, the disease was considered a purely age-related disease, but nowadays even young people suffer from this disease.

Arthritis is a serious inflammatory process in the joints and cartilage. In most cases, it occurs against the background of increased physical activity or during active and sudden movement. Symptoms of arthritis are varied, but mainly pain occurs in the damaged joint: it becomes inflamed, red and swollen. Associated symptoms are: increased body temperature, joint pain during movement or when flexing and straightening the limbs.

If even mild symptoms of the disease appear, the patient should immediately seek emergency help from a qualified doctor. It is important to remember that treatment of any ailment at an initial and mild stage can be carried out much faster and safer than curing a disease in a complicated or advanced situation. After diagnosing the disease, the doctor prescribes individual treatment for his patient.

Note: All medicinal drugs are selected taking into account the tolerance of the patient’s body, his age and the severity and complexity of the existing disease.

What remedies can cure arthritis? To treat this disease or to make the patient feel better, the following groups of medications are used:

  1. painkillers;
  2. non-steroidal anti-inflammatory drugs;
  3. chondroprotectors;
  4. traditional medicine.

Painkillers for arthritis

To relieve the painful process of arthritis, the doctor must prescribe painkillers to the patient. These medications are not able to eliminate the inflammatory process or in any way greatly influence the course of the disease, but they cope well with pain, which significantly alleviates the patient’s well-being.

In some cases, arthritis does not manifest itself in the form of severe pain, in which case the appropriate medications may not be used. But during the period of exacerbation of the disease or during its acute course, a person cannot do without taking painkillers.

Diclofenac is considered the most popular pain reliever for arthritis. In addition to it, you can use aspirin or codeine-containing drugs. Taking aspirin often has a negative effect on the gastrointestinal tract, and codeine medications can cause constipation and nausea.

Note: In addition, some drugs are incompatible with major medications used to treat arthritis. The choice of pain medication always remains with the treating doctor.

Nonsteroidal anti-inflammatory drugs for arthritis

These drugs are dominant in the treatment of this disease. The properties of non-steroidal drugs are not only to relieve the inflammatory process from diseased joints, but also to provide a high-quality and long-term analgesic effect. The advantage of non-steroidal anti-inflammatory drugs is that, while providing a healing effect on the painful area, they do virtually no harm to the body due to the fact that they have a small number of side effects.

What nonsteroidal drugs are prescribed by doctors for various types of arthritis?

  • Ibuprofen. The product is very strong, affordable and has virtually no side effects.
  • Ketoprofen. The advantage of the drug is that it is available in various variations: creams, ointments, gels, tablets, injections. Each form has an anti-inflammatory effect and is especially prescribed for rheumatoid arthritis or arthritis of the hip joint.
  • Indomethacin. Among the main drugs for the corresponding purpose, it is distinguished by its high efficiency and rapid healing properties. The product is manufactured as suppositories, gels, and tablets. All of them have an excellent anti-inflammatory effect and quickly relieve pain.
  • Meloxicam. The product has a long course of treatment and is available in any variations.
  • Celecoxib. One of the main potent drugs, it is convenient to take, as it is always available in the form of small capsules. The advantage is that the medication does not have a negative effect on the performance of the gastrointestinal tract.
  • Nimesulide. A unique remedy that not only has an anti-inflammatory and analgesic effect, but also helps to prevent damaged cartilage tissue in the joints from further destruction. Doctors have indicated this remedy for the treatment of hip joints.
  • Sulfasalazine. The drug is long-term use, the results of treatment will be noticeable after about 6 weeks, but the resulting therapeutic result is very lasting.
  • These medications are prescribed without fail together with other medications. These agents act on the diseased cartilage or joint and resist its further destruction. In addition, taking chondroprotectors slows down the activity of the disease process, and some medications help restore damaged cartilage tissue. Chondroprotectors belong to the category of healing drugs that require long-term use and use. In addition, these drugs can be taken for preventive purposes or for frequent relapses of arthritis.

    Examples of effective chondroprotectors used for arthritis.

  • Chondrotin. The product serves as a building block for the restoration of affected joints. Taking this medicine restores flexibility to the joints and improves blood supply around the cartilaginous tissues. The uniqueness of the drug is that it contains specific substances that have a detrimental effect on enzymes that destroy and destroy cartilage tissue.
  • Glucosamine. The product is based on natural ingredients; like the medicine described above, it resists joint destruction and has a restorative effect. With regular use of this drug, the elasticity of the joint tissue improves and the pain syndrome is completely eliminated.
  • Treating arthritis with alternative medicine

    Oddly enough, alternative medicine plays an important role in the treatment of arthritis. Herbs, various mixtures, pulp and juice of vegetables or fruits are used as natural preparations.

    The use of herbal remedies has excellent healing properties. This application has an anti-inflammatory, analgesic and restorative effect. The plant is unique in its use - golden mustache. An infusion is prepared on its basis, which is used for arthritis in the form of a compress, rubbing, or lotion. Analogues of the golden mustache are barberry, radish, hawthorn, and birch.

    A mixture consisting of lavender, rosemary, eucalyptus and ginger oils relieves inflammation and swelling well. It is enough to mix 2 drops of each product, and then use the resulting mixture as a cold compress or lotion.

    Baths using black pepper oil, marjoram or ginger have an analgesic effect. This medicinal bath should not be taken for more than 15 minutes.

    Whatever treatment method is used, it is important to remember that self-prescription of medications is unacceptable. All medications are prescribed only by an appropriate specialist. Folk remedies for arthritis can also be used only after careful consultation with your doctor.

    Medicines for arthrosis of the knee joint

    Treatment of arthrosis of the knee joint is a long process in which medications of different groups are prescribed. This disease is expressed in the gradual destruction of one or more joints, namely cartilage and bone tissue. In the first stages, it is amenable to drug therapy if the combination of drugs is chosen correctly. Subsequently, irreversible changes occur in the structure of the knee joint, and it can only be restored through surgery.

    Gonarthrosis and the basic principles of its treatment

    Gonarthrosis is arthrosis of the knee joint. The essence of the disease is a disruption of the nutrition and blood supply to the cartilage, as a result of which it loses its firmness and elasticity. This may occur due to age-related changes, increased physical activity, poor diet or excess weight. In addition, osteoarthritis is often a consequence of arthritis of the knee joint of traumatic origin.

    Treatment methods for arthrosis are primarily aimed at stabilizing the patient’s condition. With grades 1 and 2, you can completely stop the further development of the disease, and in some cases, restore the joint. All treatment measures should ensure knee recovery in several ways:

  • relieve pain and discomfort, which are especially intense during movement;
  • improve blood circulation in the joint area and strengthen blood vessels so that the cartilage receives the necessary amount of oxygen and nutrients;
  • reduce the pressure of bone fragments on the articular cartilage and increase the distance between them;
  • strengthen muscle tissue that will support the joint in a stable position;
  • maintain or even develop mobility in the knee joint.
  • The disease is accompanied by pain and decreased mobility of the knee. Most often, these changes occur gradually, which is why the patient does not seek medical help on time. It is recommended to combine medicinal methods of treating this disease with physical therapy, massage and physiotherapy.

    Non-steroidal anti-inflammatory drugs

    The first group of medications that are used to treat arthrosis of the knee joint are non-steroidal (non-hormonal) anti-inflammatory drugs. They can enter the body through the digestive tract or when applied to the skin, as well as in the form of intramuscular injections. Their action for arthrosis of the knee joint is as follows:

  • inflammatory processes in the joint and periarticular tissues stop;
  • the intensity of pain decreases;
  • tissue swelling is eliminated, the level of exudation is reduced;
  • The pressure of inflamed soft tissues on the blood vessels is relieved, as a result of which the nutrition of the cartilage is normalized.
  • This group includes medications such as Diclofenac, Indomethacin, Meloxicam, Ketoprofen, Nimulid and others. They are produced in the form of tablets, injection solutions or ointments for external application. The effectiveness of anti-inflammatory drugs directly depends on the method of their administration. Systemic agents (tablets, injections) penetrate the systemic bloodstream faster, and the active substances reach the site of inflammation.

    Drug treatment of arthrosis is effective only in its early stages, when the cartilage has not yet lost its ability to regenerate

    Anti-inflammatory drugs are used only in the acute stage of arthrosis. Their use is necessary in order to relieve acute pain and transfer the process to a chronic stage. Then it will be possible to proceed to other methods of treating the disease, which are contraindicated in acute inflammation - massage, gymnastics, physiotherapy. If you use anti-inflammatory drugs for a long time, they can interfere with healing. They mask the symptoms of the disease, while gonarthrosis continues to progress.

    Effective medications for arthrosis of the knee belong to a broad group of chondroprotectors. This class is represented by various products based on chondroitin sulfate and glucosamine - substances necessary for cartilage restoration. Unlike anti-inflammatory drugs, they do not simply mask the symptoms of arthrosis, but affect the cause of its development. Chondroprotectors are also available in various forms. They can be purchased in the form of tablets, ointments or injections - the effectiveness will be significantly higher when taken systemically and reduced when applied topically.

    After entering the body by any of the methods, the medicine penetrates into the damaged joint. The active ingredients are completely absorbed by the tissues of the joint and are used to restore cartilage tissue.

    Their therapeutic effects are based on the following effects:

  • division of cartilage cells - the main stage of regeneration;
  • increasing the production of joint fluid, which is necessary to support the functioning of the knee and ensure its mobility;
  • increasing the ability of articular cartilage to accumulate and retain moisture - it makes it more resilient and elastic, protects it from cracking.
  • The effectiveness of chondroprotectors against degenerative processes in joints has been confirmed by clinical trials. These drugs may have only one active ingredient or a combination of several components. However, a more complex composition does not always mean that the drug will quickly get rid of the manifestations of osteochondrosis. Medicines are selected individually, depending on the stage of the disease and the characteristics of its course.

    Chondroprotectors are drugs that will be effective only if taken for a long time. The course of treatment can last up to one and a half years in the initial stages, and in the later stages of arthrosis, medications must be taken constantly, with short breaks. To stop the acute process, intra-articular injections of these substances or their administration in the form of blockades are indicated. Then you can limit yourself to tablets or ointment with chondroitin or glucosamine.

    Chondroprotectors are a group of drugs that stimulate the restoration of cartilage tissue

    Combined chondroprotectors may contain additional components. As a rule, these are anti-inflammatory or analgesic substances, with the help of which there is a complex effect on the causes and symptoms of arthrosis. In addition, the use of combined chondroprotectors will reduce the need for other medications, which will have a positive effect on the condition of the liver.

    Popular chondroprotectors

    It is impossible to independently determine which drugs will be most effective for the treatment of arthrosis of the knee joint. They are selected taking into account test results, the stage of development of the disease and many other nuances. It is also necessary to take into account contraindications to the use of many chondroprotectors. They are usually well tolerated and do not cause side effects, but in case of stomach ulcers, kidney and liver failure, as well as during pregnancy and breastfeeding, you should refrain from using them. In addition, chondroprotectors are a broad group of drugs, which consists of 6 classes.

    There are several drugs that the attending physician is more likely to choose:

  • Artra is a drug produced in the USA in the form of tablets. Each of them contains 500 mg of chondroitin sulfate and glucosamine. For complete treatment, it is enough to take 1 tablet twice a day.
  • Dona is an Italian medicine in the form of injections, as well as powder or capsules for oral administration. It contains only glucosamine.
  • Structum is a French remedy based on chondroitin sulfate. It is available in the form of tablets that contain 250 or 500 mg of active ingredient. In the first case, you need to take 4 tablets per day; with an increased dosage, two tablets are enough.
  • Teraflex is a combination drug based on chondroitin and glucosamine, produced in the form of capsules.
  • Chondroitin - capsules, each containing 250 mg of chondroitin sulfate.
  • Elbona is a solution for intramuscular injection, containing 400 mg of glucosamine in one dose.
  • Even the best drugs against arthrosis may not be suitable on an individual basis. Chondroitin sulfate and glucosamine differ in chemical structure, so they have different effects on the damaged joint. The only way to know which medications will be most effective is to monitor the patient's condition during treatment. If the medicine does not bring results, it is replaced with another drug, which will differ in composition.

    Products for external use

    External forms of drugs are ineffective in treating arthritis. Despite the fact that many groups of drugs are produced in the form of creams or ointments, their action is not sufficient to restore joint tissue. They are useful as an additional method of treating the disease, but if used independently they will not bring results.

    Ointments are prescribed depending on the form of the disease. Arthrosis can occur with or without inflammation of the synovial membrane. This will be the decisive factor when choosing medications:

  • in case of severe synovitis, use non-steroidal anti-inflammatory ointments (Indomethacin, Fastum, Dolgit and their analogues);
  • in the absence of symptoms of synovitis, warming and irritating agents can be applied to improve blood circulation and accelerate regeneration processes (Menovazin, Espol, Nicoflex and others).
  • Ointments and gels can be prescribed as part of complex treatment of arthrosis. Thus, external use of chondroprotectors enhances the effectiveness of systemic forms of these drugs. Painkillers and anti-inflammatory ointments can relieve the symptoms of arthrosis and improve the patient’s well-being.

    Compresses show greater effectiveness in the treatment of arthrosis than ointments. The fact is that the active ingredients penetrate the joint tissues better if the drug is applied as a compress for a long time. Warming and irritating drugs are mainly used. They can be applied at the stage of chronic inflammation; in the acute phase they are contraindicated.

    Compresses are a more effective alternative to ointments and gels

    Among the most effective recipes for compresses are several:

  • Dimexide is a liquid preparation that has a pronounced anti-inflammatory effect. It penetrates well into deep tissues and has the ability to conduct other medications to the affected tissues. It also stimulates regeneration processes at the site of application, which is why it is useful to use even for arthritis with severe symptoms of synovitis.
  • Bishofite is a substance obtained during oil refining. When applied to the skin, it accelerates the resorption of arthrosis nodules and relieves inflammation. Compresses with bischofite warm up the tissue well - during the procedure you feel warmth in the knee.
  • Medical bile is an equally effective drug. It is used to resolve nodules and relieve inflammation, as well as to warm up tissues. This drug is contraindicated for purulent infections and open skin lesions.
  • In folk medicine there are also a huge number of recipes for compresses that are used to treat arthrosis. These are infusions and decoctions of herbs with anti-inflammatory and analgesic effects (chamomile, sage, calendula), as well as clay compresses. Some experts advise rubbing your knees with alcohol or herbal alcohol tinctures.

    Injections into the joint cavity

    Intra-articular injections are an emergency treatment method for arthrosis. During this procedure, medicinal substances penetrate directly into the knee joint, where they exert their effect. These can be either drugs for the symptomatic treatment of arthrosis and relief of attacks of pain and inflammation, or substances for restoring the structure of the joint. Hormonal anti-inflammatory drugs, as well as medications based on hyaluronic acid, are most often administered in this way.

    Steroidal anti-inflammatory drugs

    The only indication for the use of hormonal anti-inflammatory drugs for knee arthrosis is the acute phase of inflammation with severe exudation and swelling of the joint. In terms of their chemical structure, these drugs are analogues of the natural hormones of the human body. They participate in inflammatory processes and stop them faster than any other group of drugs.

    However, hormonal drugs should be used with caution. The course of treatment should not exceed several injections, and after swelling and acute inflammation have been relieved, it is worth changing the method of treatment. Despite its effectiveness for acute pain, this group of drugs has several features:

  • with each subsequent administration the effect becomes less pronounced;
  • with intra-articular injections, the cartilage is additionally injured by the needle;
  • they have contraindications in the form of diabetes, hypertension, stomach and intestinal ulcers, as well as purulent infection and tuberculosis.
  • Steroid anti-inflammatory drugs - Hydrocortisone, Diprospan, Kenalog, Celeston and others. They have a number of contraindications for use, and the procedure should only be performed by a competent specialist. It will not be possible to give an injection into a joint at home - it can worsen your health.

    When administered intra-articularly, drugs penetrate directly into the site of inflammation.

    Hyaluronic acid preparations

    For arthrosis of the knee joint, hyaluronic acid preparations are more preferable. The list of such products includes Giastat, Synvisc, Fermatrol and others. They do not affect the inflammatory process, but protect the joint from further destruction. When they enter the joint cavity, they act as follows:

  • perform the function of a “liquid prosthesis”, filling the joint space;
  • create a protective film on the surface of damaged cartilage and prevent it from being abraded during movement;
  • accumulate in cartilage tissue, restoring its firmness and elasticity;
  • have no contraindications, do not produce side effects and are quickly absorbed by the body.
  • Medicines for arthrosis can not only stop the disease, but also restore the knee in the early stages of the disease. For therapeutic purposes, it is common to combine several types of drugs. They come in various forms and complement each other's actions. One of the most radical methods is injection of hyaluronic acid into the joint cavity. It is more effective for arthrosis than traditional drug methods, but is expensive. In other cases, long-term treatment is indicated, alternating tablets, ointments and compresses.

    Treatment of arthrosis with drugs

    A mandatory component of the treatment of joint arthrosis is pharmacological therapy. prescribed for arthrosis, depending on the tasks performed, are divided into two large groups: for symptomatic treatment of rapid action and for restoration of the structure of articular cartilage. The first group includes nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, glucocorticosteroids, and the second group includes chondroprotectors.

    NSAIDs in the treatment of arthrosis

    Non-steroidal anti-inflammatory drugs for arthrosis are used to reduce joint pain and suppress the inflammatory process. Most often, patients are prescribed “standard” NSAIDs: diclofenac, indomethacin, aceclofenac, ibuprofen, naproxen.

    Diclofenac is a well-studied drug that has found widespread use in clinical practice. The combination of analgesic and anti-inflammatory effects, coupled with low cost, explain its popularity among patients and doctors. For arthrosis deformans, diclofenac is prescribed in tablets at a daily dose of 150 mg.

    Aceclofenac is taken for exacerbation of pain. It is also quite effective and has better tolerability compared to other drugs in its group. The daily dose of the drug is 200 mg.

    Relatively recently, a drug such as dexalgin appeared in the arsenal of doctors. Its peculiarity is that it begins to act within 30 minutes and quickly penetrates into the joint cavity. At the same time, it is also quickly eliminated from the body, which reduces the risk of many side effects. The rapid analgesic effect makes dexalgin stand out among other drugs. It is prescribed ?-1 tablet. 2-3 times a day.

    Modern representatives of the class of non-steroidal anti-inflammatory drugs have a strong analgesic effect and quickly relieve inflammation. These include nimesulide (Nimesil, Nise), meloxicam (Melox), celecoxib (Cereblex).

    In order to reduce pain and the dose of NSAIDs taken orally, anti-inflammatory ointments, gels and creams have been widely used. They often include ketoprofen (Fastum) and ortofen (Voltaren). Local therapy directly in the area of ​​the affected joint allows you to quickly relieve the symptoms of an exacerbation and avoid many side effects, which is an undoubted advantage of this form of treatment.

    It should be understood that anti-inflammatory drugs for arthrosis are symptomatic therapy; they do not stop the progression of the disease and do not heal the joints. Their long-term uncontrolled use can lead to gastropathy and ulcers of the stomach and duodenum due to the harmful effects on the mucous membranes of the gastrointestinal tract. That is why drugs in this group are taken as needed and not constantly.

    Traditionally, analgesics such as paracetamol are used to suppress pain. The daily dose is 2-4 g. If paracetamol is not effective enough and there are no signs of inflammation, you can take tramadol (tramal), which has high analgesic activity, in a daily dose of 100-200 mg.

    Glucocorticosteroid hormones

    Intra- and periarticular administration of glucocorticosteroids for arthrosis is indicated if the patient has a chronic inflammatory process and non-steroidal anti-inflammatory drugs do not relieve pain. This group of drugs, which includes hydrocortisone, Kenalog, Diprospan, has a very strong anti-inflammatory effect. However, injections into one joint are performed no more than 3-4 times a year due to the risk of disease progression. In addition, any intra-articular injections carry a risk of mechanical injury to the joint and infection. If after the first two procedures there is no effect, the very idea of ​​glucocorticosteroid therapy should be abandoned.

    Chondroprotectors in the treatment of arthrosis

    Chondroprotectors are drugs that directly affect the progression of arthrosis. Their task is to stimulate chondrocytes (cartilaginous tissue cells) to synthesize new cells to replace destroyed ones. This group of drugs is indicated for the treatment of arthrosis of the first and second degrees, since at the third stage the cartilage is destroyed and, in fact, there is nothing left to restore. Since the effect is achieved slowly, chondroprotectors for arthrosis are prescribed in long courses. In domestic medicine, preparations of chondroitin sulfate (Structum, Chondroxide), glucosamine sulfate (Dona, Stoparthrosis) and their combination (Teraflex, Arthra) are widely used. Structum is prescribed 500 mg 2 times a day for 3 months. It is recommended to conduct such courses 2 times a year.

    Remedies for arthrosis are widely represented on the pharmaceutical market. The choice is so great that the patient himself will not be able to choose the drugs he needs. Only an orthopedist can prescribe drug treatment. After all, only a specialist can decide on the choice of drugs, their dosage forms and dosages, as well as correlate this with information about the state of the body, the stage of the disease and existing contraindications.

    In our GarantKlinik medical center, arthrosis is treated by experienced orthopedic traumatologists, doctors of medical sciences, and professors. The diagnostic and treatment base allows not only conservative treatment, but also complex arthroscopic operations, as well as joint replacement. Early contact with doctors and timely treatment is the key to success in the fight against arthrosis.

    List of drugs for the treatment of arthrosis of the knee joint

    Osteoarthritis of the knee joint (gonarthrosis) is a complex disease that is not always treatable. Therefore, in this article we have prepared for you a list of medications that are most effective in treating this disease.

    Warning: all information about therapeutic agents for arthrosis of the knee joint is published solely for informational purposes for personal reference. Do not try to use them yourself without consulting a doctor: self-medication can cause irreparable harm to your health!

    All medications for the treatment of osteoarthritis of the knee can be divided into several large groups according to their mechanism of action.

    Group 1: anti-inflammatory drugs

    It is with non-steroidal anti-inflammatory drugs (NSAIDs) that the treatment of knee osteoarthritis usually begins.

    This group of drugs includes medications such as aspirin (acetylsalicylic acid), phenylbutazone, etodolac, indomethacin, sulindac, ibuprofen, piroxicam, aceclofenac, tenoxicam, diclofenac, lornoxicam, naproxen, rofecoxib, ketoprofen, meloxicam, nabumetone, tiaprofenic acid, nimesulide, flurbiprofen, celecoxib and others.

    NSAIDs vary in both their potency and the likelihood of side effects.

    These products do not contain anti-inflammatory hormones, but nevertheless, in most cases they can cope well with joint pain and reduce inflammation in them.

    Thus, ketoprofen, diclofenac, and indomethacin usually have the greatest analgesic effect, while aspirin, ibuprofen, and amidopyrine relieve pain much worse. But since many people may have individual reactions to various medications, the effectiveness of these medications may differ significantly from generally accepted norms - both in one direction and in the other.

    It is generally accepted that drugs such as indomethacin, diclofenac, flurbiprofen have the greatest anti-inflammatory effect, while ibuprofen, aspirin and naproxen, on the contrary, are less able to reduce inflammation.

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    Unfortunately, despite the fact that non-steroidal anti-inflammatory drugs usually help effectively relieve pain from osteoarthritis and other diseases, they are not very safe for health and have quite strong side effects. That is why doctors usually prescribe them in short courses and, if possible, in small doses.

    What are the dangers of taking NSAIDs?

    a) problems with the gastrointestinal tract, primarily the effect on the gastric mucosa

    Taking NSAIDs dramatically increases the likelihood of developing erosions and even ulcers of the gastric mucosa. This is especially true for people who have previously (or currently) had diseases such as gastritis and peptic ulcers of the stomach and duodenum, as well as elderly patients.

    However, recently a new generation of NSAIDs have been synthesized, in which the negative effect on the gastrointestinal tract is significantly reduced.

    This group of drugs is called selective COX-2 inhibitors and includes drugs such as nimesulide and celecoxib.

    b) kidney side effects

    NSAIDs reduce the rate of renal blood flow and also promote water and sodium retention in the body, which may contribute to increased blood pressure and the development of acute heart failure and renal failure.

    c) problems with the heart and blood vessels

    Non-steroidal anti-inflammatory drugs, among other things, also affect the blood coagulation system. If taken incorrectly, patients may develop vascular thrombosis and even stroke or myocardial infarction. Medicines that are characterized by such an effect include primarily those same COX-2 inhibitors that reduce the risk of developing gastric complications.

    Things to remember when taking NSAIDs

    As you can see, non-steroidal drugs are not at all as harmless as is commonly believed. That is why you should not prescribe such treatment for yourself, but rather consult a doctor who will select the drug and its dose that is suitable for you.

    If there is a need to take painkillers for arthrosis of the knee joint for a long time, it is better to use drugs from other groups, which, when taken for a long time, do not give such harmful side effects and have a greater selective effect, without having a negative effect on the gastric, renal or cardiovascular system. systems.

    For these purposes, drugs like movalis are more suitable, which can be taken in long courses - from several weeks to several months or more - but, of course, also only under the supervision of a doctor.

    In addition, taking NSAIDs risks the fact that it “shades out” the symptoms of arthrosis: as you know, pain is a signal from the body that something is wrong in it. If the pain is completely relieved by taking these medications, then there is a high probability that a person with such a disease will give up on the disease, relax and do nothing to recover except take pain medications.

    This approach is very dangerous because, despite the absence of pain, the disease continues to progress, the cartilage tissue continues to be destroyed, and the person may think that his health is fine and there is nothing to worry about.

    In fact, the correct approach to taking NSAIDs should be as follows: it is necessary to take these medications as prescribed by the doctor, but not in order to forget about the disease, but in order to create the opportunity to undergo complex treatment without pain in the joints: take other medications that necessary for the treatment of osteoarthritis, undergo the necessary physiotherapeutic procedures, massage courses and other therapeutic measures that would be impossible to carry out in the presence of pain.

    2nd group of drugs: chondroprotectors

    Chondroprotectors (CP) are medications that help protect cartilage tissue and enhance its formation (synthesis) in joints.

    Unlike anti-inflammatory drugs, CPs not only remove the symptoms of arthrosis of the knee joint, but also affect the very cause of osteoarthritis - they help improve the nutrition of cartilage tissue and its restoration. In this sense, chondroprotectors are one of the most important drugs for the treatment of this disease.

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    This group of products includes active ingredients such as chondroitin sulfate and glucosamine. They can be included in various combinations in various medications - such as Dona, Terafrex, Artra, Structum, Chondroxide, Elbona, Chondroitin Akos, Chondrolone, Zinaxin, Artrin and others.

    Artra is a combination drug containing equal parts of glucosamine and chondroitin sulfate (500 mg of each in one capsule). The drug is produced by the American company Unipharm; the cost of one package, depending on the number of capsules, costs from 500 to 1,700 rubles. Artra is considered one of the best chondroprotectors at the moment.

    This medicine is also a combination medicine: one capsule contains 500 mg of glucosamine and 400 mg of chondroitin sulfate, and is produced by the German company Bayer. Take Teraflex, depending on the stage of the disease, 2-3 capsules per day. It costs, depending on the number of tablets, from 600 rubles (for a package of 30 capsules) to 1500 (120 capsules) and more.

    Dona contains only glucosamine. Dona is produced in the form of sachets (sachets of powders for oral administration), capsules, and also ampoules for intramuscular administration. For the most effective treatment, manufacturers recommend combining oral administration with intramuscular injections.

    This medicine is produced by the company Rottapharm and its price ranges from 1200 to 1800 rubles - both for capsules and sachets, and for ampoules.

    This is a mono-drug of chondroitin sulfate, which is produced by the Russian pharmaceutical company Microgen. It is produced in the form of a dry substance in ampoules for dilution and subsequent intramuscular administration.

    One ampoule, which must be diluted in 1 ml of water, contains 100 mg of the active substance. Chondrolone is administered according to [information before the dose of the drug has been removed; To receive qualified treatment, consult a doctor] with a course of 25-30 injections. Its price at the beginning of 2013 ranges from 1000 to 1200 rubles per pack of 10 ampoules.

    Structum is also a mono-drug that contains chondroitin sulfate in amounts of 250 and 500 mg. Produced by Pierre Fabre Medicine Productions (France).

    It is prescribed in a dose of [information before the dose of the drug has been removed; To receive qualified treatment, consult a doctor]. A package with 60 capsules of this chondroprotector will cost you 1400-1700 rubles, or a little cheaper - as in this pharmacy.

    Elbona is a Russian product that contains only glucosamine sulfate. This medicine is available in 2 ml ampoules (plus 1 ml ampoules with solvent) for intramuscular administration; one ampoule contains 400 mg of active ingredient.

    As the name suggests, this HP is also a mono-drug containing chondroitin sulfate in the amount of 250 mg of active substance in one capsule. This medicine, like the previous one, is produced in Russia.

    This medical product contains only one active ingredient - chondroitin sulfate, but is available not only in the form of capsules (250 mg each) but also in the form of a 5% ointment. It is produced by the Russian pharmaceutical company Nizhpharm.

    For therapeutic effect, the dose of this drug, like other members of this group, should be [information before the dose of the drug has been removed; To receive qualified treatment, consult a doctor].

    A package of 60 capsules will cost 600-800 rubles. The ointment in a 30 gram tube will cost from 300 to 500 rubles (according to data from Moscow online pharmacies).

    What is important for a patient to remember when treating with chondroprotectors?

    • First of all, chondroprotective drugs are slow-acting drugs. This means that the effect of treatment develops very slowly and can only be seen after 3-5 months, and the course of treatment with these drugs ranges from 6 to 12 months and sometimes more; be patient.
    • CPs work only in the early stages of arthrosis - at degrees 1 and 2; at stage 3 of this disease, it no longer makes sense to take chondroprotectors, since all the cartilage tissue of the joint has already been destroyed and there is simply nothing to restore there.
    • There is currently no general consensus among doctors about whether it is worth taking glucosamine and chondroitin sulfate together or separately. There are studies that suggest that when these two substances are administered together, they can weaken each other's effects. But while this question remains open, it is better to leave it at the discretion of your attending physician and, if possible, give preference to products from large, reliable pharmaceutical companies with high quality products.
    • Medicines for intra-articular administration (injections into the joint)

      In addition to medications prescribed orally and intramuscularly, a great therapeutic effect for osteoarthritis is provided by the administration of various medications directly into the joint cavity (intra-articular injections). Thanks to this method of administration, the drugs directly enter the area of ​​influence - into the synovial fluid, through which the cartilage tissue is nourished.

      Most often, corticosteroid anti-inflammatory hormones are used for injection into the joint: hydrocortisone, kenalog, celeston, diprospan, flosterone and others. These drugs are injected into the joint, since when taken in tablets, such drugs have a lot of side effects. But when injected directly into the joint, they very quickly and effectively reduce pain and inflammation in the joint, alleviating the patient’s condition.

      An important point: corticosteroids, like NSAIDs, do not treat osteoarthritis, but only have an anti-inflammatory and analgesic effect. In order to truly treat this disease, it is necessary to use other drugs - the same chondroprotectors.

      Also in recent years, a treatment method such as intra-articular injection of hyaluronic acid (sodium hyaluronate) has been used. This product acts on the joint as a “liquid prosthesis” or additional synovial fluid, which seems to create a protective layer in the joint that improves movement in the joint, helps reduce trauma to the joint during movement, moisturizes the cartilage tissue and improves its nutrition.

      Sodium hyaluronate is available in the form of drugs such as fermatron, duralan, ostenil, synvisc. The therapeutic effect of administering these medications is usually very good, but, unfortunately, not everyone can afford such treatment.

      Thus, one dose of Fermatron for intra-articular administration will cost 3500-4000 rubles, while the treatment course is 3-4 injections once a week into each diseased joint. Therefore, the high price is the only factor that hinders the development of this treatment method.

      Topical medications

      Various medications used locally also have a good therapeutic effect for gonarthrosis.

      Thus, ointments such as Fastum-gel, indomethacin and butadione ointments, Menovasin, Voltaren-gel, Nikoflex-cream, Espol, diclofenac ointment and many others have proven themselves to be effective as medicinal ointments and gels for topical use.

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      They have a good therapeutic effect, but it is important to remember that only 4 to 8% of the medicinal substance passes through the skin to the “destination” - the diseased joint, therefore anti-inflammatory and analgesic treatment with ointments, creams and gels almost always needs to be supplemented with medications, taken orally or intramuscularly.

      To prepare medicinal compresses, you can use various medicinal substances for external use. These include, for example, bischofite (a petroleum derivative that has a beneficial effect on arthrosis), dimexide (an anti-inflammatory and analgesic medicine that penetrates well through the skin), as well as medical bile, which has good warming and absorbable properties.

      However, in order to keep such a complex disease as arthrosis of the knee joints under control, sometimes it is not enough just to take medications in one form or another.

      Drug treatment must be combined with physiotherapeutic procedures for joint arthrosis, sanatorium-resort treatment, and also, if your doctor does not object, you can use effective folk recipes for the treatment of gonarthrosis.

      And remember: for effective treatment of knee arthrosis, it is dangerous to self-medicate. If you experience joint pain, be sure to consult a doctor!

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      Traditional treatment of arthrosis and arthritis: remedies and recipes

      Osteoarthritis and arthritis treatment with folk remedies can be stopped, while the intensity of the pain syndrome is reduced and joint mobility improves. Arthritis and arthrosis can be treated with folk remedies without adverse effects on internal organs. This article discusses the traditional treatment of arthritis using various compresses, baths and infusions. Before using traditional treatment for arthrosis, you must visit a doctor and conduct a comprehensive diagnosis of the condition of the musculoskeletal system.

      Arthrosis is damage to the joints as a result of excessive, prolonged stress on them. Arthrosis is characterized by disruption of the activity of individual joints. Most often they occur in athletes, professional typists, and dancers.

      Arthritis is inflammation of the joints, caused by various infectious diseases (starting with sore throats) and injuries. Arthritis most often affects large joints, while arthrosis affects small joints.

      They manifest themselves in inflexibility of the joints (especially in the morning), pain in them when moving, and their deformation.

      Treatment of arthritis and joint arthrosis with folk remedies

      In addition to mandatory physical therapy (to develop affected joints, treat arthrosis of the joints with folk remedies, to improve their blood supply, but without heavy stress on them), local massage with anti-inflammatory ointments such as apisatron (with bee venom) or viprosal (containing snake venom) and with essential oils. For massage in such cases, mixtures of ginger, marjoram, frankincense, black pepper oils (1-2 drops each) or lavender, juniper, rosemary and eucalyptus oils (also 1-2 drops each) are recommended.

      It is effective to use folk remedies for arthritis of the joints, such as using baths with the addition of warming and analgesic oils (1 drop each of ginger and styrax benzoin oils and 2 drops of marjoram and black pepper oils per 1 tablespoon of olive oil).

      It is useful to take baths from a decoction of hay dust, from infusions of leaves and young shoots of black poplar. To do this, you need to collect half a bucket of shoots at the foot of a mature tree (not a sick one!), pour boiling water over them almost to the top edge of the bucket and close the lid tightly. After letting it sit overnight, pour it into the bath, add warm tap water to the desired level and immerse yourself in the bath for 20-30 minutes, then, after drying a little without drying yourself, put on a robe and go to bed.

      Another bath recipe for treating arthritis with folk remedies: take 1 glass of spruce needles, pour 2 liters of water over them and cook for 15 minutes, then add the resulting decoction to the water of the already prepared bath.

      In addition, you can make baths for the treatment of arthrosis using folk remedies according to the following recipes.

      Take 2 cups of senna leaves and pour 1 liter of boiling water, cover tightly with a lid, and leave to steep for 30-40 minutes.

      Add sea salt to the water. After using such a bath, it is advisable to rub fir oil into the heated joints, and then wrap the joints with a woolen scarf.

      Traditional recipes for the treatment of arthrosis and arthritis

      Compresses can be applied to the affected joints. Here are several folk recipes for the treatment of arthrosis and the preparation of their compositions:

      1. Take half a glass of fresh sea buckthorn berries, mash them and rub this mass into the joint (you can also do this as a compress). Despite the fact that the effect usually occurs fairly quickly and the pain begins to subside, it is best to complete the full course of treatment within 2-3 weeks (the compress can be kept overnight).

      2. Traditional recipes for the treatment of arthritis include many components. Mix 100 g of aloe juice, 200 g of honey and 300 g of vodka. Infuse this mixture for 3 days in a dark place. Apply compresses at night. The course of treatment is 7-10 days. It can be repeated if necessary.

      3. Recipes for arthritis recommend mixing 1 glass of camphor alcohol, 1.5 glasses of medical bile and 3 pods of chopped red hot pepper. Leave for 7 days in a dark place. Apply compresses in the evening or at night - for 2-6 hours, depending on the stage of the disease. The course of treatment is 7-10 days.

      And for joint pain, you can apply fresh horseradish leaves to the sore spot.

      For arthrosis, folk remedies can reduce pain; especially for arthritis, it is good to take nettle leaves, burdock root, oat straw decoction, and birch buds orally in the form of mixtures, alternating them every 2 months. At the same time, you should drink 2-3 cups of tea from mint, oregano, thyme, St. John's wort 4-5 times a day.

      The following herbal infusions can also have a good effect.

      1. Mix equal amounts of birch leaves, stinging nettle and tricolor violet herb, pour 1 tablespoon of this mixture into 1 glass of boiling water and heat in a water bath for 15 minutes. Drink half a glass 4 times a day.

      2. Mix 1 part black elderberry flowers and 4 parts each of birch leaves and willow bark. Prepare and take in the same way as the previous collection.

      3. Recipe for analgesic collection: pour 1 teaspoon of primrose roots with 1 glass of cold water, bring to a boil, simmer for 10 minutes over low heat, strain and take 1 tablespoon 3-4 times a day.

      And, of course, do not forget that your food should contain a lot of plant fiber, you should limit fats, sweets and exclude meat broths, eat more fruits and vegetables.

      Arthritis as a disease marker of osteoporosis. Types of arthritis and symptoms. Diagnosis and drugs for the treatment of arthritis

      On October 12, all countries celebrate World Arthritis Day. It must be said that this disease is currently on the rise throughout the world. People of working age from 30 to 50 years are most often affected by arthritis. It has been noted that women suffer from this disease several times more often than men. More than 20 million people on our planet suffer from rheumatoid arthritis alone. This article will focus on the disease arthritis . We will look at different types of arthritis and how arthritis is related to osteoporosis . We will talk about the symptoms of arthritis, diagnosis of arthritis , as well as various drugs for the treatment of arthritis and its prevention. Let us dwell in more detail on the diagnosis and treatment of arthritis in children. We’ll also talk about diet for arthritis ).

      What is the disease arthritis ? Arthritis is an inflammatory disease of the joints. It can be a consequence of metabolic disorders, infectious diseases and various injuries. Factors such as allergies and impaired immunity play a special role in the development and course of arthritis. The occurrence of arthritis is facilitated by hereditary predisposition and inflammatory diseases that reduce the body's resistance and weaken the immune system (frequent sore throats, inflammation of the tonsils, sinusitis and sinusitis).

      Arthritis is manifested by joint pain, which intensifies with movement, and there is a feeling of stiffness in movements. Swelling of the joints and changes in their shape may occur. The disease may be accompanied by general malaise and fever. Timely comprehensive treatment will help stop the further development of this disease.

      Arthritis is an inflammatory disease of the joints in which a person experiences pain when bending or straightening them. Arthritis is a marker disease for osteoporosis. Diseases of the joints, connective tissue and bones are directly related to each other, as they are a consequence of metabolic disorders.

      METHODS OF TREATING ARTHRITIS, DRUGS FOR ARTHRITIS:

    • NON-STEROID ANTI-INFLAMMATORY DRUGS are prescribed as antibacterial and antiviral agents.
    • LOCAL ANALGESICS are used to relieve pain.
    • SURGICAL INTERVENTION is used only in cases of complete destruction of the joints, as well as in cases where drug treatment does not bring results. The removed joint is replaced with a prosthesis.
    • SYNTHETIC CHONDROPROTECTORS for the restoration of cartilage tissue - based on hyaluronic acid, glucosamine, chondroitin sulfate.
    • NATURAL CHONDROPROTETORS - based on plants that contain substances that promote the restoration of cartilage tissue.
    • NATURAL OSTEOPROTECTORS - based on natural hormone and calcium donor substances. In Russia, natural osteoprotectors are represented by the only Osteomed line based on drone homogenate - a donor of testosterone prohormones and hormones (estrogen, estradiol, etc.), which normalize the function of the thyroid gland, normalizing metabolism. Prevention and treatment of osteoporosis is an important aspect of arthrosis treatment. Patients need to restore mineral metabolism in the body.
    • Exercise therapy - gymnastics will improve the structure of cartilage tissue, as well as improve blood supply to the joints. Strengthening the muscle corset through physical therapy will help avoid joint instability, and the load should not be excessive.
    • Note that if the results of the study reveal that one joint is damaged by arthritis, then the disease is called monoarthritis. If the disease damages several joints, it is called polyarthritis. I would like to draw attention to the fact that experts consider arthritis to be a marker disease for osteoporosis, since with delayed treatment the disease progresses and, following the destruction of cartilage tissue, destruction of the bones adjacent to the affected joint may begin.

      The disease arthritis can last a long time without visible manifestations, and symptoms appear when the joint is already severely damaged; this course of the disease is called chronic. If the disease appears suddenly, accompanied by severe pain, swelling of the joints, and fever, then this course of the disease is called acute.

      Of course, it is the elderly who suffer most from arthritis. About 60% of pensioners over 65 years of age suffer from age-related arthritis. But, as already mentioned, this disease can occur at an earlier age, even in children and adolescents. It's all about the reasons that caused inflammation and pathology of the joint. Based on this, the following types of arthritis are distinguished:

    • Rheumatoid arthritis is a disease that occurs when the immune system frequently fails. It is a chronic inflammation of the connective tissue in the body, the joints are affected symmetrically. This type of arthritis can be disabling and even disabling.
    • Reactive arthritis is a very serious disease of the joints, in which inflammatory processes occur not only in the joints themselves, it is characterized by the manifestation of inflammatory processes in the organs of the digestive system (pancreas, stomach, intestines), frequent conjunctivitis (inflammation of the conjunctiva of the eyes), inflammation of the pelvic organs .
    • Infectious arthritis is an inflammation of the joints caused by a bacterial, viral or fungal infection of the body. This type of disease has different localization (affecting different joints). In addition to the typical symptoms of arthritis, infectious arthritis is accompanied by intoxication, chills, fever, and high temperature.
    • Gouty arthritis is an inflammatory process in the joint, caused by the accumulation of uric acid in the joint tissues, which destroys cartilage and periarticular tissue.
    • Psoriatic arthritis – from the name it is clear that inflammation of the joints provokes the skin disease psoriasis. This type of arthritis still remains a mystery to specialists, as they cannot determine the etiology of the disease. Note that, along with rheumatoid arthritis, psoriatic arthritis is one of the most intractable diseases.
    • Osteoarthritis is an inflammatory disease that usually affects the cartilage tissue of the joints and later the bones that form the joint. When cartilage tissue is destroyed and thinned, the body tries to restore it, but as a result, bone tissue grows, which leads to joint destruction.
    • Traumatic arthritis is an inflammatory process in the joint that occurs as a result of injury; in this case, arthritis can be provoked not only by injuries to the joint itself, but also by injuries and bruises of the periarticular tissues.
    • Let's look at all types of arthritis in more detail.

      As already mentioned, rheumatoid arthritis is an autoimmune disease, that is, with the development of this disease, lymphocyte cells in our body, which should protect it from all kinds of viruses, pathogenic bacteria and fungi, begin to destroy the tissues of their own body, primarily the joints are affected fabrics. Scientists cannot yet give a definite answer why this happens. But factors contributing to the occurrence of rheumatoid arthritis have been identified:

    • Hereditary predisposition . Having a blood relative with rheumatoid arthritis increases the risk of the disease tenfold.
    • Another factor in the occurrence of this disease are various viral diseases : from ARVI, sore throat and influenza, to measles and viral paratitis (mumps), that is, diseases that weaken the immune system. Scientists suggest that in some cases, particles or waste products of viruses and bacteria may remain in the joints and joint fluid, which is why the cells of the immune system react to them and begin to destroy them.
    • Allergies are another factor that in some cases can trigger the development of rheumatoid arthritis.
    • Other types of arthritis . Rheumatoid arthritis can be caused by reactive, infectious or traumatic arthritis.
    • Stress , severe nervous shock and anxiety can also cause this disease.
    • According to experts, the occurrence of the disease can be significantly influenced by hormonal disorders , as well as the influence of certain substances: various toxic substances, waste products of various microorganisms (toxins), the influence of tobacco.
    • Disturbances in the balance of sex hormones , when female sex hormones dominate over male ones, autoimmune disorders occur.

    Symptoms of rheumatoid arthritis

    I would like to note that the symptoms of rheumatoid arthritis are recognizable:

  • Initially, rheumatoid arthritis usually affects small joints (fingers, wrists).
  • In rheumatoid arthritis, joints are most often affected symmetrically (for example, the elbow joints on both arms).
  • The pain intensifies at night and persists in the first half of the day, in the second half of the day the person feels better, and at night everything repeats.
  • The temperature of the skin over the diseased joints increases during an exacerbation.
  • The longer the disease progresses, the larger joints it affects. I would like to note that rheumatoid arthritis is often the starting point of osteoporosis; one of the reasons for this phenomenon is the damage and destruction of bone tissue adjacent to the diseased joint.
  • With rheumatoid arthritis, impaired motor activity, stiffness, usually appears in the morning, after a while it goes away.
  • Often during an exacerbation, this disease can be accompanied by fever, weakness, and loss of appetite.
  • A typical symptom of rheumatoid arthritis is dense subcutaneous growths in the affected joints, so-called rheumatoid nodules, which may spontaneously appear and disappear.
  • Over time, due to rheumatoid arthritis, persistent deformation of the joints occurs, first of all, the fingers and hands are affected; this process is accompanied by impaired blood supply and gradual muscle atrophy, as a result, over time, a person can no longer serve himself, since the mobility of the joints may be completely lost .
  • History of traumatic injuries.
  • Obesity.
  • Dental diseases caused by viral infections.
  • Infections of ENT organs.
  • Autoimmune diseases.
  • Metabolic disorders.
  • Allergic reactions.
  • High blood pressure.
  • Osteoporosis.
  • Pneumonia.
  • Echinococcal bone lesions.
  • Psoriasis.
  • Tuberculosis.
  • Pathology of the parathyroid glands.
  • Disorders of the central nervous system.
  • Bites of some insects, wasps, bees, ticks, etc.
  • Living in an unfavorable environmental environment.
  • Excess body weight, which puts significant stress on the joints.
  • FOR DENTAL PROBLEMS:

  • Persistent bleeding of gums.
  • Loose teeth in the lower jaw.
  • Periodontal disease.
  • ACCORDING TO THE CONDITION OF HAIR AND NAILS:

  • Vertical grooves on the nails.
  • Delamination of the nail surface.
  • Hair loss.
  • Professional activities are often associated with significant stress on the joints or hypothermia.
  • Athletes.
  • Dancers.
  • Post-traumatic arthritis can be caused by a fracture.
  • Crunching in the joints during physical activity.
  • Swelling and redness of the tissue around the joint.
  • Low-grade fever.
  • Painful sensations when moving joints.
  • Sharp pain at the end of the day, even at rest.
  • Deformation of joints.
  • Limitation of mobility.
  • Interview and examination of the patient.
  • Blood tests
  • Test for anticitrullinated antibodies.
  • Puncture of joint fluid.
  • Arthroscopy.
  • X-ray of the joint.
  • Scintigraphy.
  • Treatment of rheumatoid arthritis

    Treatment of rheumatoid arthritis should be comprehensive and carried out in several areas: treatment of the underlying cause of the disease, anti-inflammatory therapy, normalization of the function of the immune system, local therapy, physiotherapeutic treatment.

    The main goal of any therapy is to eliminate the cause of the disease in the first place. I would like to note that in the case of rheumatoid arthritis, the long-term goal of treatment is to stop the development of this disease. Returning the patient the opportunity to live a full life. Of course, a complete cure for rheumatoid arthritis is impossible, but it is quite possible for modern medicine to stop its development, with timely diagnosis.

    Let's look at the types of drugs that are used in the treatment of rheumatoid arthritis.

  • Gold-based preparations. Now they are practically not used anymore. But they have been used to treat arthritis for more than 80 years. They did not produce immediate results; their action was aimed at stopping the disease. Courses of taking such drugs are quite long, ranging from a month or more. Their main disadvantage was that in combination with them a person was forced to take painkillers. Note that the effect of gold is more effective in the early stages of the disease. It was used when anti-inflammatory therapy did not bring results.
  • Gold preparations have a number of serious side effects: inflammation of all mucous membranes (throat, intestines, oral ulcers), non-infectious hepatitis, “golden” dermatitis. Another serious side effect is “golden” nephropathy (severe kidney damage). It is because of severe side effects that these drugs are no longer used in the treatment of arthritis.

  • It is not surprising, but to normalize the function of the immune system in the treatment of rheumatoid arthritis, immunosuppressive drugs (Methotrexate) are used. The same ones that are used in the treatment of cancer. In the treatment of rheumatoid arthritis, immunosuppressants are used in very small dosages. It must be said that precisely because of the small dosages, side effects from treatment with these drugs are quite rare. At the same time, they provide tangible positive results.
  • Drugs of the sulfonamide group (“Sulfasalazin”). These drugs have an antibacterial effect; they inhibit the growth of various pathogenic microorganisms. Sulfonamide drugs are well tolerated by patients; the side effects of these drugs are mild and infrequent. The disadvantage is the long course of treatment, up to six months or longer. The effectiveness of these drugs is lower than that of gold-based drugs and immunosuppressive drugs.
  • The listed types of drugs are aimed at stopping the development of the disease and have a cumulative effect. What should a person who is suffering from pain do now? As already mentioned, complex treatment is used for rheumatoid arthritis. In addition to basic drugs, anti-inflammatory drugs are used.

    • The first group of anti-inflammatory drugs used in the treatment of rheumatoid arthritis are the non-steroidal anti-inflammatory drugs Ibuprophenum. Drugs in this group have the following properties: antipyretic, analgesic, anti-inflammatory. They are used as emergency aid for severe joint pain. These remedies do not have a therapeutic effect; they temporarily relieve symptoms. The advantage of these drugs is their rapid pain-relieving effect, but drugs in this group have many contraindications and side effects (they can be toxic to the body).
    • Another group of anti-inflammatory drugs is selective drugs (“Meloxicam”). These drugs are considered a new word in medicine. Selective drugs have virtually no side effects, since they act locally and fight inflammation only in cartilage tissue. Drugs in this group can be used for long courses, but under the supervision of a specialist. The main disadvantage of this group of drugs is that they increase blood clotting, which can cause heart attacks and strokes. For this reason, selective drugs are prescribed with drugs that prevent blood clots.
    • In the treatment of rheumatoid arthritis, corticosteroid drugs (Prednisolone) are also used. Drugs in this group are hormonal drugs. Currently, there is a lot of controversy regarding the use of corticosteroids for the treatment of rheumatoid arthritis. On the one hand, drugs in this group have a very rapid positive effect , but it does not last very long, after which the disease returns with renewed vigor. In addition, these drugs have a lot of side effects, they affect the entire body. Hormonal drugs can provoke metabolic disorders, hormonal imbalance, immunity disorders and even stomach ulcers To reduce the negative effects of corticosteroids, they are used locally in the form of injections directly into the joint. But even in this case, such drugs can cause another serious disease - osteoporosis. The fact is that corticosteroid drugs cause active loss of bone mass.
    • In addition to immunosuppressant drugs, other types of regulation of the immune system function are used in the treatment of rheumatoid arthritis, such as blood plasma transfusion, irradiation of lymphoid tissue with X-rays and intravenous laser irradiation of blood.

    • Blood plasma transfusion is understood as a process during which a large amount of plasma, which contains the bulk of rheumatoid factors, is mechanically removed from the human body. At the same time, the patient is injected intravenously with donor blood plasma. This method gives a quick positive result. Among its disadvantages: the occurrence of edema and a possible decrease in hemoglobin. I would also like to note the fairly high cost of such a procedure.
    • Radioactive irradiation with X-rays destroys cells - lymphocytes, causing the destruction of their own tissues. This irradiation is done in stages, first the lymph nodes are irradiated, then the spleen, then the thymus gland. This procedure also gives a fairly quick result; a stable remission occurs, which can last one and a half to two years. The disadvantages of this method are obvious - radioactive X-rays are not at all harmless
    • Intravenous irradiation of blood with a laser beam. To carry out this procedure, a special probe is inserted into a vein located in the elbow. The laser destroys rheumatoid factors, thus the immune system is stabilized, and the disease enters an inactive phase.
    • Very often, in the complex therapy of rheumatoid arthritis, local treatment is also used, which may include: local laser irradiation, cryotherapy and the use of various ointments and creams.

    • Local laser irradiation is used for chronic disease. The affected joints are directly irradiated. This treatment gently relieves inflammation.
    • The best local treatment, according to experts, is cryotherapy. Deep cooling is used to treat all forms of arthritis. This type of treatment is absolutely harmless and has no contraindications or side effects. Cryotherapy can be used both topically and in the form of a cryosauna. Both procedures will undoubtedly have a positive effect, but cryosauna is more expensive. For local cryotherapy, liquid nitrogen is sprayed under pressure onto the affected area, which quickly evaporates and cools the area; the body's response is to improve blood supply to the area, resulting in reduced inflammation. The cryosauna uses dry cold air. This procedure is usually prescribed when most joints are affected.
    • Painkillers and anti-inflammatory ointments and creams. This type of treatment gives only a minor effect, since the skin can only allow a small amount of active ingredients to pass through. This is clearly not enough to obtain a lasting result.
    • Please note that in the complex therapy of rheumatoid arthritis, physiotherapeutic methods and massage are used only during the period of stable remission of the disease. The fact is that during an exacerbation, physiotherapy and massage can worsen the condition and increase inflammation.

      I would like to note that both during exacerbations and during remission of rheumatoid arthritis, it is recommended to use natural complexes, such as Dandelion P, in complex therapy. (dandelion is a natural handroprotector) and Osteomed , which will have a complex effect on the body: it will help restore hormonal levels, have a positive effect on the immune system and prevent osteoporosis.

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