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Medicine for varicose veins Detralex

06 Jun 18

How to take Detralex for varicose veins: instructions and recommendations

Varicose veins are a pressing problem that occurs with enviable frequency in many people. As a result of this disease, swelling of the legs, blood clots and inflammatory processes appear, leading to serious problems.

It is for this reason that it is necessary to quickly provide appropriate treatment in order to keep your feet in a beautiful and healthy condition. Many patients note in their reviews that treatment of varicose veins with the drug Detralex gives positive results regardless of the stage of the disease.

The components of the drug increase the tone of the veins, reduce their stretching, thin the blood plasma and stop the formation of thrombosis and thrombophlebitis. This is a unique remedy that can really cure varicose veins, in some cases forever.

Let's look at the features of using Detralex for varicose veins in more detail.

The medicine is available in the form of oval tablets with a dose of 500 mg. The coating is made in the form of an orange shell, which makes it convenient to drink tablets. Detralex contains almost 90% of the active substance diosmin.

And the remaining 10% is made up of the second active ingredient - hesperedin and excipients, namely:

  • microcrystalline cellulose;
  • sodium carboxymethyl starch;
  • magnesium stearate;
  • gelatin;
  • purified water.
  • Phlebological prescription of medication

    The main purpose of Detralex is the treatment of varicose veins. During the period of varicose veins, there are disruptions in the blood flow of the veins, causing the formation of blood clots, nodes and swelling of the legs.

    If timely treatment is not provided, unpleasant consequences may occur, including death. Therefore, it is necessary to take Detralex at the first stage of varicose veins, at the first signs of varicose veins.

    Phlebologists also prescribe medicine for the following problems:

    • constant pain in the legs;
    • when cramps occur in the limbs;
    • when you feel heaviness in your legs;
    • when trophic inflammation occurs on the surface of the skin;
    • during hemorrhoidal attacks;
    • when seals appear in the veins.
    • The effect of the drug on the veins and the body as a whole

      Detralex is a phlebotropic type drug with a highly effective effect. It has a complex effect on the human body. The two active components of the product Diosmin and Hesperidin have the following actions:

    • Diosmin enhances the tone of the veins, reduces the permeability of vessel walls, resists stagnation of blood in the veins, accelerates blood flow, and reduces hydrostatic pressure in the veins;
    • Hesperdin has a strengthening effect on the walls of blood vessels and accelerates the outflow of blood.
    • In addition, the main components are combined with other substances, so the product has the following effects on the body:

    • the medication suppresses the effect on prostaglandins E2, E26 and thromboxane B2, which cause inflammatory processes;
    • has antioxidant properties, the drug stops the appearance of free radicals that cause damage to the walls of blood vessels;
    • preventing the adhesion of leukocytes to the walls of blood vessels and their further penetration into surrounding tissues;
    • decreased number of white blood cells in inflamed tissues;
    • reducing the level of release of toxic substances - leukotrienes, cytokines and oxygen superoxides;
    • positive effect on blood microcirculation.
    • Dosage regimen depending on the disease

      In accordance with the instructions for use, Detralex should be taken based on the condition and severity level of the pathology:

    • For varicose veins, the drug should be taken twice a day. At lunchtime you should take 1 tablet with a meal, and 1 tablet in the evening with dinner. Take the tablets with plain water. The course of treatment with the drug for varicose veins is 2 months. It all depends on the severity of the disease, so it’s still worth getting examined by a doctor so that he can make the necessary appointments.
    • During chronic venous insufficiency, the drug is taken twice a day, 2 tablets - at lunchtime and in the evening. After a week of treatment, the intake can be reduced - 1 tablet twice a day.
    • In case of acute forms of phlebological diseases, take the drug 2 times a day. At lunchtime and evening, 3 tablets. After a week, you can reduce the number of tablets to 1, take them twice a day.
    • During thrombophlebitis and postthrombophlebitis syndrome, the drug should be taken twice a day, 2 tablets - at lunchtime and in the evening. Then after 7 days, take it twice a day, but 1 tablet. But still, in this case, this is only an auxiliary treatment, so you should be examined by a doctor so that he can prescribe complex therapy. Detralex for thrombophlebitis is taken only for preventive purposes. The period of treatment with tablets is about six months.
    • During the preoperative and postoperative period of phlebectomy, the medicine is taken 2 times a day, 2 tablets. Before the operation, the drug should be taken for a month and a half. In the postoperative period it is taken for up to 3 months, it all depends on the severity of the operation.
    • Treatment recommendations

      During the course of treatment of varicose veins with Detralex, it is advisable to use complex therapy.

      It is advisable to follow these tips during the treatment period and after the final stage of therapy to maintain the achieved results and prevent recurrence of the disease:

    • Compression stockings must be worn . The density and level of compression of the stockings should be selected by a specialist, therefore, during the selection, both the severity of the disease and the physical parameters of the patient (height and weight) are taken into account. Compression stockings are worn daily and removed only before bed. They should be put on in the morning while lying on the bed.
    • It is imperative to control your body weight . Excess body weight can put additional stress on your legs, which can ultimately lead to problems with blood circulation and lymphatic drainage.
    • Regulate motor functions throughout the day . Namely, rest and activity should alternate. It is not advisable to sit or lie in one place for more than 3 hours. Lying, sitting, walking should alternate.
    • Every day you need to do special exercises for your legs , which will improve blood flow. These exercises should be prescribed by a specialist.
    • Contraindications and restrictions

      Despite the fact that the constituent components of the drug are of natural origin and absolutely safe for the human body, there are still indications for which it is not advisable to take Detralex tablets:

    • Children and adolescents under 18 years of age , because there is no data on the effect of the constituent components on the children's body.
    • Allergic reactions to the constituent substances of the drug.
    • During breastfeeding . Taking pills by nursing mothers should only be done under the close supervision of a phlebologist and pediatrician. It is also best to take the drug at this time only if it is absolutely necessary.
    • During pregnancy, you can take the drug, but still only in serious cases and when absolutely necessary. According to studies, the components of the drug do not have a harmful effect on the body of the mother and child.

      But many doctors recommend taking Detralex during this period only in emergency cases.

      In rare cases, side effects may occur when taking the medicine:

    • various manifestations of an allergic nature - urticaria, skin rashes, Quincke's edema;
    • disruption of the digestive system - nausea, painful feelings in the abdomen, constipation, diarrhea;
    • neuralgic disorders - dizziness, frequent headaches, feeling of weakness, frequent fatigue.
    • Detralex is a time-tested medicine. It really proves its effectiveness and can quickly cure varicose veins. Many patients in their reviews note positive qualities after the first days of treatment for varicose veins with Detralex.

      Of course, in order for the treatment to be successful and positive, it is necessary to first be examined by a specialist, and only after his conclusion and recommendations can you begin further treatment of varicose veins.

      Venotonic drug Detralex - complete instructions for use, reviews of doctors and patients about the medicine

      Detralex belongs to the category of venotonics . This drug is based on flavonoids - substances of plant origin.

      The active components are hesperidin and diosmin, thanks to the action of which it is possible to eliminate venous congestion of various origins.

      Thanks to the use of Detralex, it is possible to restore tone and microcirculation of blood in small vessels. At the same time, the capillaries become more elastic and plastic, their fragility decreases. In addition, it is possible to establish lymphatic drainage.

      Detralex is produced in the form of yellow-pink film-coated tablets.

      The drug has a venotonic and angioprotective effect. At the venous level, Detralex helps reduce the distensibility of veins and reduce venous congestion. At the level of blood microcirculation, it reduces capillary fragility, reduces vascular permeability, and also increases their resistance.

      In people with symptoms of capillary fragility, capillary resistance increases after treatment with Detralex. It can also be used to improve venous tone.

      Pharmacokinetics of the drug

      Detralex is mainly excreted from the body in feces. Approximately 14% of the drug taken is excreted in the urine. The elimination half-life requires 11 hours.

      At this time, the drug undergoes active metabolism, and this confirms the presence of phenolic acids in the urine.

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      When to use the medicine

      Detralex is used in the following cases:

      Symptomatic treatment of venous-lymphatic insufficiency. The drug eliminates the following manifestations of the disease:

    • pain;
    • feeling of heaviness in the legs;
    • cramps, morning tired legs;
    • trophic disorders;
    • symptomatic treatment of exacerbation of hemorrhoids.
    • There are also contraindications to the use of this drug:

    • The presence of a hypersensitivity reaction to the components of the drug. Information about this may be present in the patient's medical history.
    • Lactation period. It is not recommended to use the drug during breastfeeding due to the small amount of information regarding the likelihood of active components getting into milk.
    • Pregnancy. During this period, Detralex should be used with extreme caution and be sure to consult a doctor.
    • Age less than 18 years. There are no data regarding the use of Detralex in children.
    • How the drug works

      Detralex is part of the group of angioprotectors - drugs that help improve the functioning of blood vessels.

      Therefore, it is used for the treatment of diseases accompanied by venous stagnation, impaired vascular permeability, and deterioration of blood circulation in the capillaries.

      Detralex also has an antioxidant effect, as it prevents the formation of free radicals, which are one of the main factors in damage to the walls of blood vessels.

      The drug improves the tone of the veins, reduces their distensibility, eliminates venous congestion and promotes lymph outflow.

      Detralex also normalizes blood flow in the capillaries and prevents the formation of blood clots.

      How to use correctly

      Let's study the instructions for use of Detralex.

      Detralex should be taken with food.

      Recommended dosage

      The instructions for use indicate that Detralex tablets are taken in different doses depending on the disease.

    • To treat manifestations of chronic venous insufficiency, you need to take 2 tablets per day. It is recommended to take one tablet during the day, and the second in the evening. After a week of using the drug according to this regimen, you can switch to another regimen: a single dose of two tablets per day.
    • For the treatment of chronic hemorrhoids, take 2 tablets per day. This should be done in two steps. After a week, you are allowed to switch to a single dose of two tablets.
    • To treat acute hemorrhoids, take 6 tablets per day for four days. Then take 4 tablets per day for three days. In this case, the daily dose should be divided into two or three times.
    • The duration of treatment is determined by the indications and characteristics of the course of the disease. Usually the course is about 2-3 months.

      Overdose and additional instructions

      What else you need to know about Detralex.

      The use of the drug Detralex can cause disturbances in the functioning of the digestive system - dyspepsia, diarrhea, nausea, vomiting. In rare cases, colitis occurs. In addition, neurological disorders sometimes appear - headache, general malaise, dizziness.

      In rare cases, Detralex causes the development of urticaria, skin rash, and itching. In exceptional situations, angioedema appears.

      However, no cases of drug overdose have been recorded in medical practice.

      Experimental studies did not reveal a teratogenic effect of the drug. Clinical studies have not revealed data that indicates a negative effect of Detralex on the fetus.

      Therefore, the drug can be used in the third trimester.

      In case of exacerbation of hemorrhoids, the use of Detralex cannot replace the specific treatment of other pathologies of the anorectal area. Acute hemorrhoids are treated with a short course under the supervision of a specialist.

      Reviews from patients and doctors

      Reviews from doctors and patients about the drug Detralex are mostly positive. Here are some of them:

      1. I used Detralex to treat thrombophlebitis. The result was very pleasing - the drug demonstrated its high effectiveness. In addition, it is well tolerated by the body. But for this you should follow the doctor’s recommendations.
      2. I really liked the drug Detralex. In just a month, it helped cope with aching pain in the legs and eliminate swelling. Since I have a predisposition to chronic venous diseases, the doctor advised me to take the drug in courses - twice a year.
      3. Detralex is an excellent drug. It is, of course, a little expensive, but it gives amazing results. I take it as a support for vein diseases 2 times a year. As a result, the aching pain in my legs stopped bothering me. The effect can be maintained even in the intervals between courses of treatment.
      4. Pros and cons based on reviews and practical experience

        The advantages of Detralex include:

      5. high efficiency;
      6. no serious side effects;
      7. Possibility of use during pregnancy.
      8. The disadvantages are :

      9. high cost;
      10. the need for long-term use.
      11. Reviews of the drug Detralex during pregnancy

      12. During pregnancy, I developed a hemorrhoid, which was accompanied by serious discomfort. The proctologist prescribed the drug Detralex. Literally after the first dose I felt an improvement. After finishing the course the problem completely disappeared.
      13. Many women experience hemorrhoids during pregnancy. This problem appeared in my third month, but after suppositories and creams it disappeared. However, in the ninth month the disease returned again. The doctor prescribed me to take Detralex, and already on the third day the nodes shrank significantly. In addition, there was practically no trace of pain left. I recommend Detralex to all pregnant women - it is an excellent venotonic.
      14. Forms of release and price in rubles

        Detralex is produced in the form of film-coated tablets. One tablet contains 450 mg of diosmin and 50 mg of hesperidin.

        The tablets are packaged in blisters, each containing 15 pieces. There are 2 or 4 blisters in a cardboard box.

        The price for a package of 30 Detralex tablets is about 700 rubles. 60 tablets will cost about 1,300 rubles.

        Complete analogues of Detralex are the drugs Venarus and Venozol.

        Partial analogues include Phlebodia 600, Vasoket.

        Other venotonics are Antistax, Troxevasin, Venoruton, Anavenol, Ginkor fort.

        Video: Detralex is one of the best medicines for varicose veins

        What is the therapeutic effect of Detralex based on and why is the drug so effective in the treatment of varicose veins. The drug affects the very essence of the disease.

        I took Detralex when I was diagnosed with varicose veins. The diagnosis is not the most “pleasant”, but quite removable. Detralex helped me cope with varicose veins very well. I take it periodically in courses for prevention, especially during periods when I have to spend a lot of time on my feet.

        I used Detralex when my hemorrhoids worsened, the pain was terrible. I took a course of Detralex and the hemorrhoids stopped bothering me. The composition of these tablets is natural. Now I drink it for preventative purposes 2 times a year, the hemorrhoids have not returned.

        I also have varicose veins, just a couple of weeks ago I started taking this remedy, I want my legs to be beautiful in the summer

        Can leg swelling get worse when taking pills? I have been taking it for 2 weeks according to the instructions: 1 tablet 2 times a day, according to the instructions it is possible to take 2 tablets once a day, and at what time is it better?

        I have been taking Detralex for three weeks. For a week now (more precisely, 5 days) I have had very high blood pressure - 170-185 mmHg. Can this medicine cause high blood pressure?

        Quite often I saw Detralex in reviews. that it causes nausea and increases blood pressure - that’s why I didn’t buy it - I chose Venarus - there are no such side effects from it

        Venarus this my mother had side effects wow, if you don’t believe me, read the instructions. and Detralex, thank God, has been helping her feel good for over a year now. Previously, even because of pain symptoms, I couldn’t walk or stand for a long time, but now she walks for two to three hours a day

        Dear! side effects can arise from taking any drug, but no one has canceled it - individual intolerance... I know about venarus that it only has a distracting effect, but in general it is necessary to wear the right shoes and control your own weight!

        Sonya, your advice is good, but what if heredity, for example, is like this? Do your mothers, grandmothers or great-grandmothers have varicose veins or did they have them? the probability is very high that you will develop varicose veins, even if you spend your whole life barefoot and skinny

        Here! You're right! Ours is hereditary: my grandmother had it, my mother only started at the age of 40, and for me it started at the age of 25, immediately after giving birth. And weight doesn’t really matter! I am 174 cm tall and weigh 58 kg. It seems to me that I am not obese.

        And I thought that I would have to have an operation to remove varicose veins. But the doctor said that this was already an extreme stage and prescribed Detralex. My course was not easy and long, since I set myself reminders in my phone for the entire three months so as not to forget to take the pills twice a day. But it gave results. The pills helped me a lot. Also, while I was taking Detralex, I was losing weight with Modelform 30+ at the same time. After losing weight, my legs definitely felt better.

        If side effects occur from Detralex, do they go away after discontinuation?

        Does Detralex increase blood pressure? I have a STAND in my heart artery with cholesterol around 3 and calcified vessels. Can Detralex be used?

        For some reason, after taking Detralex, I felt suffocated. Should I continue to take it?

        I take warfarin, can I use Detralex?

        Good evening. I started taking Detralex as prescribed by my doctor. I'm taking the pill for the second week. Today I noticed that the veins on the legs (in particular below the hips, on the thighs) became even worse visible than they were before starting the drug... is this a side effect or the effect of the drug that will eventually eliminate this cobwebby blue mesh on the legs?! the veins are clearly visible and visible on both legs... has anyone encountered this problem? I haven’t noticed any other contraindications yet...thank you very much in advance for your answer.

        I have the same thing, veins began to be visible on my thighs. How are things going with you now?

        Natasha, although this answer to you may be very late, still! Detralex, in order for it to be beneficial, you need to take 2 tablets TWO times a day! And so the first week! No less than 7 days! And then cut down and drink 1 tablet. in the morning with breakfast, and one in the evening, later, at night. Got it? So that you are saturated with it all day. At first there is increased concentration - because it is very much removed from the body. In the morning you ate/drank, and by the evening it’s no longer in you! Therefore, at night - a new portion. And only after 7-8-9 days of taking 4 tablets per day can you reduce saturation - drink one tablet with breakfast and one later at night. BUT ! Be sure to eat with food: a little something in your mouth, and then a tablet—lots of water === 4-5 sips of water. FURTHER it’s even more difficult: you need to take the bare minimum—19 days. Until you see the effect! Because it will become noticeable after 18 days of strict\\continuous (a break ruins everything right away and you have to start all over again!). It’s only after you take 56-60 tablets that you can see a noticeable improvement. And at a price of 234.80 rubles, or even worse—30 rubles per tablet, that’s 1,680 rubles to spend before you see the first signs that things are getting better! But find the money\\allocate it from the family budget (if you are alone, it’s easier for you) and buy it right away, don’t regret it. The consequences are not only DANGEROUS (if left untreated), the worst thing is that they are IRREVERSIBLE! If you reach ulcers on the skin, and even worse, blood clots in a vein, then you are either crippled forever with ulcers or - DEATH is inevitable from a blood clot that comes off partially and gets stuck in the lungs or heart. Look in pharmacies - go around all there are in your city, don’t be lazy! I bought the first ones for 450 rubles per plate of 15 tablets. And I looked and found it - 373 rubles for 15 tablets. The difference is noticeable, as you can see.

        Nata, hello! If the question is still relevant, remember: when taking Detralex you must (.) wear compression garments (stockings, knee socks). Voach repeated this to me several times. I listened to it and there were no problems, I’ve been taking courses for the 2nd year. I don't walk, I fly. I wish the same for you.

        I have been taking Detralex tablets twice a day for two weeks. The itching is terrible in my legs, especially in the lower area, and the drug itself helps a lot, the heaviness and pain are almost gone. Before this I took phlebodia and there was no such effect. What should I do? I scratched my legs until they turned red .Please advise.

        be careful, it disperses the lymph, your legs itch with Hodgkin's lymphoma, and all lymphatic dispersers are prohibited, do an ultrasound of the lymph nodes, God forbid this sore. (personal experience, my daughter was sick)

        I took Detralex for 4 months. The blood pressure returned to normal. The pulse is about 70. But the hemoglobin became 150. When I donated blood from my finger, it splashed on the table. I read that it should be thick. Is this an overdose?

        I took Detrolex for one week and developed leg cramps. There have never been any before.

        Storage: 15-25C (room temperature)

        Shelf life: 48 months.

        Detralex instructions

        Detralex (micronized flavonoid fraction Diosmin + Hesperidin) is an original drug from the group of venoprotectors and venotonics. Manufacturer: Servier Laboratory (France), one of the oldest pharmaceutical companies in the world. Available in tablets. The uniqueness of Detralex lies in the fact that it is the only micronized drug in medical practice today. The diameter of the microparticles forming the tablet is 2 microns or less, which allows diosmin to be absorbed from the digestive tract four times faster and have a pronounced positive effect on venous and lymphatic drainage just 4 hours after taking 2 tablets (1 g). For comparison: the “colleagues” of the drug in the pharmacological group in a non-micronized form have a therapeutic effect only 1-2 days after administration.

        Detralex is used as a venotonic and angioprotector. It reduces the distensibility of venous walls, facilitates venous outflow, reduces the permeability of capillary vessels, and increases their ability to maintain integrity under damaging influences. The results of multicenter clinical trials demonstrate the effectiveness of the drug in the treatment of venous hemodynamic disorders. The effect of Detralex in relation to such venous plethysmographic indicators as the capacity of the venous bed, the distensibility of the venous wall, and the time of emptying of the venous system has been statistically confirmed. Clinically, the therapeutically optimal dose/action ratio was determined - 1000 mg (2 tablets). Detralex has proven effectiveness in the treatment of chronic venous insufficiency of the lower extremities and hemorrhoids. The drug also has a fairly strong anti-inflammatory effect. It is based on blocking the production of key inflammatory mediators - prostaglandins and thromboxane. The antioxidant properties of Detralex are determined by its ability to prevent the appearance of aggressive free radicals that damage the walls of blood vessels.

        One of the factors contributing to the development of an inflammatory focus is an increase in capillary permeability, mass migration of white blood cells and phagocytosis, due to the activation of complement at the initial stage of inflammation. The drug prevents the adhesion of leukocytes to the internal lining of blood vessels, blocks their migration to the site of inflammation and prevents the release of components that have a damaging effect - free radicals, cytokines, leukotrienes, proteolytic enzymes. According to this mechanism, the direct protective effect of Detralex on the microvasculature of patients suffering from chronic venous insufficiency develops. A number of independent sources call Detralex the only venotropic drug with proven effectiveness, leaving out horse chestnut preparations. It affects all pathogenetic patterns of venous diseases: the tone of the venous walls, lymphatic outflow, microcirculation. The drug is effective at any stage of the development of chronic venous insufficiency, from the incubation stage to the occurrence of severe complications.

        The main route of elimination of Detralex is through feces (urine accounts for only about 10% of the dose taken). Its half-life is 11 hours. Subjects to active metabolic transformation in the liver. Available exclusively in tablets with a dosage of 1000 mg, 30, 60, 90 pieces per package. It is administered orally. The optimal time to take it is in the morning, with food. The duration of drug therapy can be up to 1 year. In case of relapse of the disease, with the permission of the doctor, a repeated treatment course is allowed. If there is no improvement in the clinical picture for a long time, you should consult a proctologist. Cases of pharmacological interaction with other drugs have not been recorded.

        One of the best drugs Detralex: instructions for use, price and analogues

        The cardiovascular system bears the main burden in a person's daily life. During physical activity and even quiet walking, the vessels are in good shape and play a role in ensuring blood circulation.

        Cell nutrition, heart function, and the presence of blood stagnation depend on the condition of the blood vessels, so it is very important to monitor and maintain their health. The drug Detralex was developed specifically for these purposes. Therefore, let's talk about the drug Detralex: instructions for use, price, and its analogues.

        The poor condition of blood vessels and the lack of substances useful to them leads to depletion of the vascular wall and an increase in the diameter of the lumen.

        This is typical for venous vessels, which bear the main load, ensuring blood flow from bottom to top throughout the human body.

        A thinned vessel wall and an expanded lumen leads to an increase in load and the formation of pathological local expansions - nodes.

        Superficial nodes are clearly visible on the lower extremities of a person, and those located more deeply are hidden to the naked eye. However, such pathological aneurysm-like enlargements pose a great health hazard.

        The combination of such changes in the vascular wall is called varicose veins, which many have heard about, but do not know how to avoid it.

        Varicose veins are dangerous for the following reasons:

      15. Inflammation and swelling appear at the site of vasodilation. This limits the patient’s movements due to pain and deterioration of the general condition.
      16. Inflammation leads to blood clots, which can be fatal if they affect large and deep veins.
      17. An inflamed superficial vessel can become adherent to the skin, and minimal damage leads to severe bleeding.
      18. In areas of expansion, stagnation forms, which disrupts the nutrition of cells and provokes the appearance of ulcers.
      19. In the later stages, treatment of varicose veins is only possible through surgery, so it is very important to notice the problem in a timely manner. An effective remedy for the conservative treatment of varicose veins is the drug Detralex.

        pharmachologic effect

        The main component of Detralex are flavonoids, which are represented by diosmin and hesperidin.

        Flavonoids are plant substances of natural origin, known for their positive effect on blood vessels.

        Thus, Detralex promotes the effect of:

      20. increasing vascular tone;
      21. strengthening the vascular wall;
      22. reducing the distensibility of veins;
      23. reducing congestion and increasing microcirculation;
      24. increasing vascular resistance to adverse factors;
      25. improving lymphatic drainage and outflow.
      26. Indications for use of Detralex tablets

        What does Detralex treat? Speaking about reducing congestion and strengthening the walls of blood vessels, it is worth noting varicose anal veins, which are called hemorrhoids.

        Drugs from the group of venotonics, which includes Detralex, are very effective in solving such delicate problems and are widely used in medical practice.

        Thus, the indications for use of the drug Detralex are:

      27. Venous insufficiency, which manifests itself as heaviness or pain in the legs, increased fatigue.
      28. Varicose veins and its initial stage in the form of a spider vein.
      29. Haemorrhoids.
      30. The drug contains natural ingredients that are found in many berries, vegetables and fruits. The active components, as a rule, are very well tolerated by all categories of patients. Contraindications can only be individual intolerance to the main or auxiliary ingredients.

        Almost never observed. Very rarely there may be complaints about :

      31. dyspeptic symptoms that soon go away on their own;
      32. minor neurological disorders – malaise, dizziness;
      33. skin reactions - rash, itching.

    Detralex tablet release form

    Detralex is available in tablet form. The package may contain 30 or 60 pieces. On average, a large package is enough for a month's course of taking the drug. Detralex does not exist in the form of ointment, cream or gel.

    How to take Detralex? Before or after meals. Doses and frequency of administration may vary depending on indications. It is recommended to take the drug with meals.

    Instructions for Detralex tablets:

  • The standard dosage of Detralex for the treatment of venous insufficiency is 2 Detralex tablets per day, which are best taken in two doses. How long to take? The duration of the course of treatment is determined by the doctor. Most often this lasts about 3 months. How to take it for the prevention of varicose veins, the drug is taken for 1 month, and after a while it is repeated.
  • In the acute stage of inflammation of hemorrhoids, the course of taking Detralex should be a daily dose of 6 tablets for the first 4 days. After relief of symptoms, the daily dose is reduced to 4 tablets and the course is continued for another 3 days. After relief of the acute condition, they switch to a maintenance dose, which is 2 tablets per day.
  • Chronic hemorrhoids require longer treatment. In this case, the daily dose is not increased and remains standard (2 tablets).
  • Preventive courses of treatment are repeated twice a year. This is recommended for people with a sedentary lifestyle, initial problems of venous outflow, and risk groups (work related to stress on the legs). Duration of administration is 1 (60 tablets).
  • The load on the legs and venous vessels increases during pregnancy. Detralex is approved for use during this period and can significantly improve a woman’s condition. However, consultation with a doctor is required.

    Compatibility with other drugs

    The drug is well compatible with all other drugs. There is no separate research data on this issue, but over many years of successful use of Detralex, no cases of incompatibility have been reported.

    Features of application

    How to take Detralex correctly? You should know several important points during treatment:

  • Detralex is best used in the complex treatment of hemorrhoids. It does not replace specific treatment and does not cancel compliance with the necessary diet. The effectiveness of treatment is determined by a proctologist.
  • In case of venous insufficiency, the course of treatment with Detralex should be combined with compliance with certain recommendations regarding the patient’s lifestyle. You should reduce the load on your legs, ensure that you maintain the correct weight, and limit your exposure to the sun. Walking is considered beneficial To mechanically maintain the tone of the veins and reduce the load on the walls of the venous vessels, it is recommended to wear compression garments.
  • The drug is allowed to be used by pregnant women, but the final decision is made by the doctor. During lactation, it is better to refrain from taking the drug due to the lack of data regarding its penetration into breast milk.
  • Detralex does not have a negative effect on fertility or concentration.
  • Detralex and alcohol are compatible, but simultaneous use significantly reduces the effectiveness of therapy.
  • The drug belongs to the over-the-counter group and can be purchased at a pharmacy without a prescription.
  • Prices per package of Detralex:

  • In Ukraine: about 250 UAH for 60 tablets;
  • In Russia: Detralex price of 60 tablets is about 1300 rubles; price 30 tablets 800 rubles.
  • What to replace it with? Quite a lot of analogues of this drug have been developed. They are in different price ranges, so all categories of patients will be able to choose a suitable venotonic agent.

    Below is a small list of cheaper analogues of Detralex:

    You can find out the differences between Phlebodia and Detralex in this article.

    Visually familiarize yourself with the operating principles of Detralex:

    How to take Detralex for varicose veins: rules and restrictions

    Varicose veins are a disease that creeps up unnoticed and is not particularly disturbing in the initial stage. However, effective drug treatment is possible at this stage.

    Detralex for varicose veins is one of the most effective means for preventing irreversible complications. The longer you do not notice the beginning of problems with the veins, the faster the pathology covers your vessels.

    In advanced stages, your legs undergo irreversible changes. In them, the blood supply is disrupted to such an extent that areas of numbness, changes in skin color, and ulceration occur. It is possible to treat legs at these stages only with the help of surgery. Advanced varicose veins seriously undermine the quality of life.

    Detralex for the treatment of varicose veins

    The course of treatment for varicose veins with Detralex ranges from one to three months. Such courses require from 2 to 4 per year. Such a long period of therapy is explained by the mild but steady restorative and tonic effect on the veins. In some cases, the drug may be prescribed for a year without a break.

    A phlebologist will prescribe exactly how to take Detralex for varicose veins after a thorough examination of the condition of the veins.

    Detralex is a herbal preparation. Available in tablet form (500 mg). It is prescribed orally. The tablets are oblong in shape with a line in the middle. Color ranges from yellowish to pink.

    The main active ingredients are flavonoids:

    1. Diosmin (450 mg) – is a venotonic, angio and venoprotector. It reduces the permeability of the vascular wall and prevents its stretching. Effectively enhances blood supply to both large and peripheral vessels. Stimulates the reverse flow of blood and lymph. Selectively accumulates in the large veins of the legs and the inferior vena cava. The therapeutic effect of the dose taken lasts up to 96 hours.
    2. Hesperidin (50 mg) - has similar medicinal properties to diosmin. However, unlike it, it helps lower blood pressure. It relaxes blood vessels and bile ducts. Increases coronary blood flow. Neutralizes allergic reactions.

    Both active ingredients are independent medicines. They can be purchased at a pharmacy with a prescription. Reviews of Detralex for varicose veins indicate a mutual enhancement of the medicinal qualities of diosmin and hesperidin in precisely this combination and dosage.

    How to take the drug?

    How to take Detralex for varicose veins is individually prescribed by your doctor. But since the drug is over-the-counter and can be purchased at a pharmacy if desired, you should study the official instructions for using Detralex for varicose veins. It describes the classic regimens for taking the drug, contraindications and possible side effects.

    Indications for use

    The main indication for Detralex therapy is the presence of pathological changes in the veins - their expansion and degeneration of the walls. As a result, normal blood flow is disrupted. The process is closed. Violation of the reverse outflow of blood leads to increased pathological processes in the veins.

    The official instructions for use of Detralex for varicose veins recommend the drug for the following symptoms:

  • Persistent swelling of the legs, which does not decrease much after a night's sleep;
  • Pain in the legs, aggravated by physical activity or at the end of the day;
  • Feeling of heaviness, fullness, pulsation in the legs;
  • Night cramps, cramps when the foot is tense, from fatigue;
  • Change in skin color on the foot, lower leg in the presence of the above symptoms;
  • Trophic ulcers;
  • Inflammation of hemorrhoids.
  • Detralex for varicose veins (especially in its early stages) can significantly slow down the destruction of blood vessels, stimulating reverse blood flow and toning the vascular walls. It effectively relieves symptoms, improving the patient's quality of life. By taking this drug, the patient is able to live a normal life while maintaining working capacity.

    It is recommended to take Detralex with food. The dosage and duration of taking the drug varies depending on the severity of the patient’s condition and the diagnosis. How long to take Detralex for varicose veins to prevent relapse of the disease, for treatment “at the height” of the disease or for hemorrhoids is found in the instructions.

  • Preventive intake – 2 times a day, 1 tablet, morning and evening. Two weeks after the start of treatment, you can switch to a single dose, reducing the total daily dosage by half. Course – 1 month every six months.
  • Treatment of varicose veins of initial and moderate degree - 2 times a day, 1 tablet, morning and evening. Course from 1 month to 3. Annual course options: quarterly, 1 month, 4 times a year. Or 2 every 2 months 3 times a year. The last option is 3 months after 3 2 times during the year.
  • Treatment of hemorrhoids. Acute form - 2 tablets 3 times a day, breakfast, lunch, dinner. Enhanced therapy for no more than 4 days. Further treatment: 4 tablets in two doses, morning and evening.
  • Detralex is contraindicated in children under 18 years of age, since there is no official data on its action (harm or long-term effects) on the children's body.

    Pregnant women can use the drug only in the third semester, strictly as prescribed by a doctor, after assessing the risk.

    Detralex is not prescribed to nursing mothers, since there is a possibility of transmitting it to the baby through milk.

    A contraindication is individual intolerance to the components of the drug, which usually becomes clear only after the start of use. If you experience any allergic reactions or illnesses that you associate with taking this product, you should immediately consult a doctor.

    Reviews of Detralex tablets for varicose veins indicate that the most common negative reactions are from the gastrointestinal tract. This:

  • Nausea, vomiting (very rare);
  • Abnormal stool, flatulence (rare);
  • Heaviness in the stomach, discomfort after eating, heartburn, pain (noted more often).
  • Side effects from the digestive system are often explained by neglect of the instructions for using Detralex for varicose veins. The need to take the drug with meals, indicated in it, is aimed precisely at avoiding such effects.

    In addition, the following may be noted:

  • Dermatological allergic manifestations: rash, redness, itching (moderate);
  • Headaches (often at the beginning of treatment, but there is a strong tendency to reduce them during treatment).
  • If you notice changes in your health that you associate with taking Detralex, contact your doctor. Perhaps it is better for you to switch to some analogue of this drug.

    The original drug is produced in France. The domestic pharmacological industry offers a complete analogue of Detralex for varicose veins - Venarus. This medicine contains the same flavonoids diosmin and hisperidin, in similar concentrations. The only difference is the manufacturer and price. Russian venotonic is somewhat cheaper.

    Partial analogues of Detralex: Phlebodia, Venolek, Diovenor, Vasoket, Venorus, Diosmin. These are single-component preparations based on diosmin. They have a similar effect in the symptomatic treatment of varicose veins and inflammation of hemorrhoids.

    The action similar to Detralex, but with other active ingredients is based on the drugs Troxerutin, Troxevasin, Antistax.

    Special instructions not included in the Detralex instructions

    Reviews indicate that Detralex tablets for varicose veins “work” much more effectively if in parallel:

  • Stop smoking. There is no greater “killer” for your blood vessels than a cigarette. The combination of “smoking and varicose veins” very quickly leads to leg amputation. This is especially true for men.
  • Reduce excess weight. Losing 5 kg dramatically increases your chances of maintaining healthy legs.
  • Walk actively. Walking (not running!) promotes the drainage of stagnant blood and lymph no worse than the most effective medicine.

    Reviews about treatment with Detralex

    The doctor prescribed Detralex when she could no longer walk without crying. My legs were very swollen and painful. The first month showed the effectiveness of the medicine. The swelling is almost gone. My legs began to hurt much less and only in the evening. The only thing that spoils the treatment is the high cost of Detralex. The course costs almost 1,500 rubles for a month. 4 courses are needed per year.

    I bought the medicine myself at the pharmacy, without a prescription. I just read a lot of reviews about Detralex for varicose veins of the legs. Spider veins appeared during pregnancy, and swelling increased with age. I could no longer wear heels for more than an hour. I took the tablets according to the instructions in the minimum dose. The swelling has gone away. Now I’m thinking of trying phlebodia, there are also very good reviews about it.

    Lately my legs have been cramping. Especially caviar at night. A neighbor suggested Detralex to my wife. We bought it, although it was a little expensive. The tablets help very well. They make my stomach hurt. But you can be patient; healing your legs is more important. I think I will take them regularly to ensure complete health for my legs.

    How to take Detralex for varicose veins: the effect of the drug, recommendations

    Varicose veins of the lower extremities are not only discomfort from the appearance of the veins in the legs, but also symptoms that reduce the quality of life: pain, swelling, night cramps, trophic ulcers. They are the ones who bring patients to the doctor for help, and then to the pharmacy, where the most popular drug is Detralex and its analogues. To answer the question of how to take Detralex for varicose veins and get rid of the disease, we will first consider the reasons that contribute to the appearance of the disease.

    Causes of varicose veins of the legs

    The causes of the disease consist of several factors:

  • Upright walking. The blood should rise vertically upward against gravity from each toe to the heart, which, depending on the person’s height, is up to one and a half meters.
  • Genetic predisposition. The presence of varicose veins, hemorrhoids, thrombophlebitis or other connective tissue pathologies among blood relatives.
  • Anatomical features of blood vessels. Minor muscular component of the venous wall, adjacency of large vascular trunks of the legs directly to the skin.
  • Overweight. The greater the body weight, the more blood in the veins of the legs.
  • Pregnancy and childbirth. In addition to the growing body weight while expecting a baby, the uterus puts pressure on the vascular trunks of the abdominal cavity, complicating the outflow from the lower extremities and pelvis, and the hormone progesterone reduces the tone of the vascular wall. When the fetal head passes through the natural birth canal, it completely blocks the outflow for a certain period of time, and pushing forces a large volume of blood into the lower half of the body. In addition, during pregnancy and childbirth, changes in the blood coagulation system occur, which can lead to a complication: thrombosis of varicose veins.
  • Features of lifestyle. Lack of cyclic movements (walking, running, cycling, swimming), the need to spend a lot of time standing (teachers, salespeople, hairdressers, surgeons, etc.) or sitting (office workers) without the opportunity to do exercises.
  • Bad habits. Alcohol abuse, smoking.
  • Recognizing the disease is not difficult. Symptoms and signs are obvious and usually appear as follows:

  • telangiectasia (spider veins, spider veins);
  • nodular or saccularly dilated saphenous veins;
  • swelling of the legs and feet in the evening, if one limb is affected, it is visually much thicker than the healthy one, fluid retention can reach one and a half liters;
  • trophic disorders, lipodermatosclerosis (coarsening, darkening, thinning, dry skin and subcutaneous fat due to constant increased pressure in the veins, a decrease in the speed of blood flow in the capillaries preceding them and the inability to adequately nourish the tissues of this area);
  • trophic ulcer (tissue nutrition is disrupted to such an extent that a skin defect that is difficult to heal is formed).
  • In addition, already from the first stages of the disease, patients are bothered by a feeling of fatigue, heaviness in the legs, bursting pain, and cramps at night.

    All these symptoms are explained by pathological changes in the blood vessels. Chronic congestion of the veins triggers an inflammatory process in the vascular wall:

  • stagnation activates leukocytes of venules - transitional blood vessels from capillaries to large veins;
  • leukocytes fuse to endothelial cells - cells lining the vessels from the inside;
  • endothelial cells respond by releasing inflammatory and adhesion molecules;
  • due to this, leukocytes “stick” and “leak” through the spaces between the cells from the lumen of the blood vessel into the surrounding tissues;
  • the interaction of leukocytes and endothelial cells leads to the production of free oxygen radicals, which weakens the vein wall and venous valves;
  • insufficient valve function increases stagnation, closing a vicious circle.
  • Varicose veins require an integrated approach to treatment: an individual combination of lifestyle correction, medication and surgical treatment.

    Medicines against varicose veins

    Several groups of drugs are used to prevent complications and treat varicose veins:

  • phlebotonics - micronized purified flavonoid fraction (Detralex and generics);
  • hydroxyrutosides (“Troxevasin” and analogues);
  • diuretics (diuretics);
  • means for improving microcirculation;
  • medications against platelet aggregation (sticking together);
  • non-steroidal anti-inflammatory drugs.
  • Phlebotonic agents have earned the greatest respect among phlebologists and vascular surgeons. Their use at any stage of the disease makes it possible to break the vicious circle of damage to the vascular wall, and most importantly, to improve the patient’s well-being.

    There is a large selection of phlebotonics on the pharmacy counter, these are:

    Looking at the instructions for use, it is difficult to find the differences. It is important that Detralex tablets for varicose veins are the original drug, and the rest are analogues or generics.

    The pharmaceutical company that produces this medicine develops it in its laboratory and conducts clinical trials. All this requires large financial costs, so original drugs are usually imported and expensive. When several years pass after the first sales, approval for the production of generic drugs comes into force. Then small pharmaceutical companies copy the composition of the medicine and instructions without spending their own money on it, so generics are inferior in price. The main question remains: are the analogues of sufficient quality and effectiveness? The answer is ambiguous. It depends both on the integrity of the manufacturer and on the technical capabilities of pharmaceutical companies; not only the active substances, but also the excipients are important in the composition of the tablet. Doctors who use them in everyday practice are best informed about the work of original drugs and generics.

    The unanimous opinion of phlebologists and vascular surgeons: drinking Detralex means taking tablets that definitely contain the most effective and safe phlebotonic agent. It has been proven that Detralex also helps well with pelvic varicose veins and hemorrhoids.

    Mechanism of action of Detralex

    The main point of application is the wall of the venous vessel:

    • taking Detralex increases the tone of the veins;
    • blood stagnation in the lower extremities decreases;
    • lymphatic drainage improves;
    • microcirculation in the capillaries and macrocirculation in large venous trunks are normalized.
    • In addition, Detralex blocks the interaction between endothelial cells and leukocytes, suppressing inflammatory processes, thus reducing damage to the vein wall and valves.

      The main active ingredients are active flavonoids (polyphenols of plant origin):

      A specialist will determine how to properly take Detralex for varicose veins. The duration of the course and dosage are selected individually and can reach 12 months or more.

      How and how much to take the medicine

      Detralex is available in tablets. For the treatment of varicose veins of the legs, the following scheme is most often used:

    • 2 tablets per day (1 in the morning with breakfast, and the second in the afternoon with lunch or in the evening with dinner);
    • course of treatment - 1 month;
    • The drug should be repeated 2 times a year.
    • Maximum effectiveness is observed when combined with conservative therapy methods.

      According to the instructions for use, there is insufficient data on the safety of use during pregnancy and lactation. Side effects are rare: disorders of the digestive system and allergic reactions to the components are possible. Detralex is available in pharmacies without a prescription.

      How to achieve maximum effect

      When treating varicose veins, you will have to make adjustments to your lifestyle.

    • Control your body weight and avoid carrying heavy objects.
    • Stop drinking alcoholic beverages and smoking tobacco.
    • Cyclic sports are encouraged (walking, running, swimming, cycling).
    • Adjust your work and rest schedule, alternate sedentary work with active work.
    • Master special gymnastics for the feet and legs, which can be performed at the workplace.
    • Set aside 15 minutes during the day to lie down with your legs thrown up higher.
    • Refuse stockings and tight belts, any wardrobe items that tightly encircle the leg or stomach.
    • Do not sit cross-legged.
    • Contrast shower for feet in the morning and evening. Avoid baths, saunas and excessive insolation.
    • Remember that patients with varicose veins of the legs are at risk for hemorrhoids (avoid constipation and flatulence).
    • Wear well-chosen medical knitwear and take medications on time. Do not use hormonal drugs as contraception.
    • Your attending phlebologist will tell you how to take Detralex correctly for varicose veins. You should not be afraid of prescribing the drug even for a long time; it is a highly effective therapeutic and prophylactic agent with a minimum of side effects.

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